original ) (raw )Peptidyl transferase antibiotics perturb the relative positioning of the 3′-terminal adenosine of P/P′-site-bound tRNA and 23S rRNA in the ribosome
Stanislav Kirillov
RNA, 1999
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Fine Structure of the Peptidyl Transferase Centre on 23 S-like rRNAs Deduced from Chemical Probing of Antibiotic-Ribosome Complexes
Ricardo Amils
Journal of Molecular Biology, 1995
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A mutation in the 530 loop ofEscherichia coli16S ribosomal RNA causes resistance to streptomycin
Claude Lemieux
Nucleic Acids Research, 1988
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Context-specific inhibition of translation by ribosomal antibiotics targeting the peptidyl transferase center
Emily Roncase
Proceedings of the National Academy of Sciences, 2016
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Mutations in eukaryotic 18S ribosomal RNA affect translational fidelity and resistance to aminoglycoside antibiotics
Yury Chernoff
The EMBO Journal, 1994
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Mechanisms of Resistance to an Amino Acid Antibiotic That Targets Translation
Michael Ibba
ACS Chemical Biology, 2007
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UV-induced modifications in the peptidyl transferase loop of 23S rRNA dependent on binding of the streptogramin B antibiotic, pristinamycin IA
Stanislav Kirillov
RNA, 1999
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A new mutation in 16S rRNA of Escherichia coli conferring spectinomycin resistance
Diarmaid Hughes
Nucleic Acids Research, 1995
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Quantitative Binding of Antibiotics to Ribosomes from a Yeast Mutant Altered on the Peptidyl-Transferase Center
Antonio Jimenez
European Journal of Biochemistry, 1975
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Mutations in Domain II of 23 S rRNA Facilitate Translation of a 23 S rRNA-encoded Pentapeptide Conferring Erythromycin Resistance
Tanel Tenson
Journal of Molecular Biology, 1996
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Mutations Outside the Anisomycin-Binding Site Can Make Ribosomes Drug-Resistant
Susan Schroeder
Journal of Molecular Biology, 2008
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Effect of mutations in the A site of 16 S rRNA on aminoglycoside antibiotic-ribosome interaction
Stephen Douthwaite
Journal of Molecular Biology, 1999
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Resistance mutations generate divergent antibiotic susceptibility profiles against translation inhibitors
Scott C. Blanchard
Proceedings of the National Academy of Sciences of the United States of America, 2016
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Elements of ribosomal drug resistance and specificity
Yury Polikanov
Current Opinion in Structural Biology, 2012
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Binding of Neomycin-Class Aminoglycoside Antibiotics to Mutant Ribosomes with Alterations in the A Site of 16S rRNA
E. Westhof
Antimicrobial Agents and Chemotherapy, 2006
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E. coli ribosomes with a C912 to U base change in the 16S rRNA are streptomycin resistant
Paul-Etienne Montandon
The EMBO Journal, 1986
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Interaction of antibiotics with A- and P-site-specific bases in 16S ribosomal RNA
Maura Cannon
The Embo Journal, 1991
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Puromycin–rRNA interaction sites at the peptidyl transferase center
hien phan
Rna-a Publication of The Rna Society, 2000
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The macrolide-ketolide antibiotic binding site is formed by structures in domains II and V of 23S ribosomal RNA
Stephen Douthwaite
Molecular Microbiology, 1999
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Phenotypic suppression of streptomycin-resistance by mutations in multiple components of the translation apparatus
Joshua Jaspers
Journal of Bacteriology, 2015
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Interaction of Ac-Phe-tRNA with E. coli ribosomal subunits. 2. Resistance of the sparsomycin-induced complex to hydroxylamine action
David Contreras Vazquez
FEBS Letters, 1970
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Correlation between the peptidyl transferase activity of the 50 s ribosomal subunit and the ability of the subunit to interact with antibiotics
Zvi Vogel
Journal of Molecular Biology, 1971
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Erythromycin, Roxithromycin, and Clarithromycin: Use of Slow-Binding Kinetics to Compare Their in Vitro Interaction with a Bacterial Ribosomal Complex Active in Peptide Bond Formation
G. Dinos
Molecular Pharmacology, 2003
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A novel site of antibiotic action in the ribosome: Interaction of evernimicin with the large ribosomal subunit
Tanel Tenson
Proceedings of The National Academy of Sciences, 2001
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Altered ribosomes in spiramycin-resistant mutants of Bacillus subtilis
Asad Ahmed
Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 1968
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Biochemical and kinetic characteristics of the interaction of the antitumor antibiotic sparsomycin with prokaryotic and eukaryotic ribosomes
Ana Felix
Biochemistry, 1991
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Binding of aminoglycoside antibiotics to helix 69 of 23S rRNA
Paul Agris
Nucleic Acids Research, 2010
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Evidence for functional interaction between domains II and V of 23S ribosomal RNA from an erythromycin-resistant mutant
Stephen Douthwaite
Proceedings of the National Academy of Sciences, 1985
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Cooperative and Antagonistic Interactions of Peptidyl-tRNA and Antibiotics with Bacterial Ribosomes
David Vazquez
European Journal of Biochemistry, 1977
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A functional peptide encoded in the Escherichia coli 23S rRNA
Alexander Mankin
Proceedings of the …, 1996
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Binding site of macrolide antibiotics on the ribosome: new resistance mutation identifies a specific interaction of ketolides with rRNA
Georgina Garza-Ramos
Journal of …, 2001
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