Total chemical synthesis of a functional interacting protein pair: The protooncogene H-Ras and the Ras-binding domain of its effector c-Raf1 (original) (raw)

Design, total chemical synthesis, and binding properties of a [Leu-91-N1-methyl-7-azaTrp]Ras-binding domain of c-Raf-1

Jens Sydor, Martin Engelhard

Proceedings of the National Academy of Sciences, 1999

View PDFchevron_right

Benzimidazolinone-Free Peptide o-Aminoanilides for Chemical Protein Synthesis

Abhisek Kar

View PDFchevron_right

A sensitive fluorescence monitor for the detection of activated Ras: total chemical synthesis of site-specifically labeled Ras binding domain of c-Raf1 immobilized on a surface

Christie Hunter

Chemistry & Biology, 2001

View PDFchevron_right

Photoaffinity labeling of Ras converting enzyme 1 (Rcelp) using a benzophenone-containing peptide substrate

Kelly Kyro, Surya Manandhar

Bioorganic Medicinal Chemistry, 2010

View PDFchevron_right

Effect of Tertiary Bases on O-Benzotriazolyluronium Salt-Induced Peptide Segment Coupling

Ayman El-Faham

Journal of Organic Chemistry, 1994

View PDFchevron_right

Synthesis of Cyclic Peptides Constrained with Biarylamine Linkers Using Buchwald−Hartwig C−N Coupling #

Javed Iqbal

The Journal of Organic Chemistry, 2006

View PDFchevron_right

Synthesis of Functional Ras Lipoproteins and Fluorescent Derivatives

Benjamin Bader

Journal of the American Chemical Society, 2001

View PDFchevron_right

Contemporary Methods for Peptide and Protein Synthesis

Saburo Aimoto

Current Organic Chemistry, 2001

View PDFchevron_right

Chemical synthesis of proteins: a tool for protein labeling

Lucia Rosa

2010

View PDFchevron_right

Enzymatic Synthesis of C -Terminal Arylamides of Amino Acids and Peptides

Claudia Cusan

The Journal of Organic Chemistry, 2009

View PDFchevron_right

Modification and Activation of Ras Proteins by Electrophilic Prostanoids with Different Structure are Site-Selective

Andrea Perez

Biochemistry, 2007

View PDFchevron_right

Synthesis of fluorescent d-amino acids with 4-acetamidobiphenyl and 4-N,N-dimethylamino-1,8-naphthalimido containing side chains

Jyotirmoy Maity

Tetrahedron Letters, 2015

View PDFchevron_right

Introduction of unnatural amino acids into proteins using expressed protein ligationStandard IUPAC single- and triple-letter codes for amino acids are used throughout the article

Julio Camarero

Biopolymers, 1999

View PDFchevron_right

A methodology for simultaneous fluorogenic derivatization and boronate affinity enrichment of 3-nitrotyrosine-containing peptides

Nadya Galeva

Analytical Biochemistry, 2011

View PDFchevron_right

Oxyma: An Efficient Additive for Peptide Synthesis to Replace the Benzotriazole‐Based HOBt and HOAt with a Lower Risk of Explosion [1]

Ayman El-Faham

… A European Journal, 2009

View PDFchevron_right

ChemInform Abstract: Aminoacyl Benzotriazolides: Versatile Reagents for the Preparation of Peptides and Their Mimetics and Conjugates

Siva S Panda

ChemInform, 2014

View PDFchevron_right

Chemical Methods for Peptide and Protein Production

Istvan Toth

Molecules, 2013

View PDFchevron_right

Synthesis and characterization of oligonucleotide peptides

Kirby Sample

The Journal of Organic Chemistry, 1991

View PDFchevron_right

Synthesis, molecular docking and anticancer studies of peptides and iso-peptides

Tamara Kondratyuk

Bioorganic & Medicinal Chemistry Letters, 2015

View PDFchevron_right

The diisopropylcarbodiimide/1-hydroxy-7-azabenzotriazole system: segment coupling and stepwise peptide assembly

Ayman El-Faham

Tetrahedron, 1999

View PDFchevron_right

Efficiency in Peptide Coupling: 1-Hydroxy-7-azabenzotriazole vs 3,4-Dihydro-3-hydroxy-4-oxo-1,2,3-benzotriazine

Ayman El-Faham

Journal of Organic Chemistry, 1995

View PDFchevron_right

Synthesis of peptides with α,β-dehydroamino acids, VI. Synthesis ofN-benzyloxycarbonyl andN-trifluoroacetyl dipeptides of α,β-dehydro-butyrine, -valine, -leucine, and -isoleucine

Piotr Wieczorek

Liebigs Annalen der Chemie, 1988

View PDFchevron_right

The Use of Aryl Hydrazide Linkers for the Solid-Phase Synthesis of Chemically Modified Peptides

Julio Camarero

ChemInform, 2007

View PDFchevron_right

Application of N-(tert-butyloxycarbonyl)amino acid N-carboxyanhydrides in solid-phase peptide synthesis

Fred Naider

The Journal of Organic Chemistry, 1993

View PDFchevron_right

Assessment of new 6-CI-HOBt based coupling reagents for peptide synthesis. Part 1: Coupling efficiency study

Ewelina Renz

View PDFchevron_right

Addition of HOXt (X= A or B) improves the efficiency of phenol-based coupling reagents during peptide synthesis

Ayman El-Faham

Letters in Peptide Science, 2000

View PDFchevron_right

Synthesis of 5-(((R,S)-5-((9-Fluorenylmethoxycarbonyl)amino)-10,11-dihydrodibenzo[a,d]cyclohepten-2-yl)oxy)valeric Acid (CHA) and 5-(((R,S)-5-((9-Fluorenylmethoxycarbonyl)amino)dibenzo[a,d]-cyclohepten-2-yl)oxy)valeric Acid (CHE) Handles for the Solid-Phase Synthesis of C-Terminal Peptide Amides ...

Kiyoshi Nokihara

The Journal of Organic Chemistry, 1994

View PDFchevron_right

DNA-instructed acyl transfer reactions for the synthesis of bioactive peptides

Tom Grossmann

Bioorganic & Medicinal Chemistry Letters, 2011

View PDFchevron_right

Peptides Frontiers of Peptide Science

Pravin Kaumaya

Springer eBooks, 2002

View PDFchevron_right

Bis(4,6‐dimethoxy‐1,3,5‐triazin‐2‐yl) Ether as Coupling Reagent for Peptide Synthesis

Zbigniew J Kamiński

Chemistry & Biodiversity, 2013

View PDFchevron_right

Use of Onium Salt-Based Coupling Reagents in Peptide Synthesis1

Ayman Faham

The Journal of Organic Chemistry, 1998

View PDFchevron_right

Utilization of N,N,N′,N′-Tetramethylfluoroformamidinium Hexafluoro­phosphate (TFFH) in Peptide and Organic Synthesis

Sherine Khattab

Synlett, 2009

View PDFchevron_right

Conformationally Constrained Functional Peptide Monolayers for the Controlled Display of Bioactive Carbohydrate Ligands

sabrina antonello

Langmuir, 2013

View PDFchevron_right

Identification of ras/raf binding site and design of interfering peptide with potential clinical application

Severine Loisel

Integrative molecular medicine, 2016

View PDFchevron_right