Microbial Profile and Antibiograms of Active Patients of Chronic Suppurative Otitis Media in Latur, Maharashtra, India (original) (raw)
Related papers
https://www.ijhsr.org/IJHSR\_Vol.6\_Issue.3\_March2016/11.pdf, 2016
Introduction: Chronic suppurative otitis media (CSOM) is the most common infection of the ear characterized by recurrent, purulent discharge from the middle ear through a nonintact tympanic membrane. Its incidence has remained relatively higher in developing countries Aim/Objectives: This study was carried out in department of Microbiology, Dr.S.C.G.M.C, Nanded to determine bacteriological profile and its antibiotic susceptibility in patients with CSOM Materials & Methods: A total of 470 patientsaged 2-60 years admitted to ENT ward from July 2014 to April 2015 were studied. Ear swabs were taken and cultured aerobically on blood agar and Mac Conkeyagar. The organisms isolated were identified by standard microbiological methods and antibiotic sensitivity pattern was determined Results: Out of 470 patients, 245(52.12%) were female and 225(47.87%) were male. Peak prevalence of otitis media was documented in age group 2-10 years (39.41%). Amongst 470 ear swabs, 460(97.87%) were culture positive and 30(6.52%) were having 2 isolates. Pseudomonas aeruginosa (37.95%) was the commonest isolate followed by Staphylococcus aureus (21.83%), Coagulase Negative Staphylococcus (18.16%), Klebsiella pneumoniae (15.51%) and Escherichia coli (8.36%). Antibiotics sensitive to P. aeruginosa were Imipenem (100%), Gentamicin (65.2%) and Tobramycin (61.7%) and those resistant were Ceftazidime (71.6%) and Piperacillin (59%). Both K. pneumoniae and E. Coli species showed highest sensitivity to Amikacin (96.8%) and Ciprofloxacin (65.3%) and resistance to Amoxyclav (62.2%), Cefotaxime (61.8%) and Ceftriaxone (61.3%). Amongst Gram positive isolates, Vancomycin (100%), Clindamycin (64.3%) and Cefoxitin (53.9%) were highly sensitive and Penicillin (11.2%) was most resistant drug Conclusion: Routine use of topical antibiotics for any case of CSOM as empirical therapy must be reviewed and judicial use of antibiotics is recommended to minimise antibiotic resistance
International Journal of Otorhinolaryngology and Head and Neck Surgery, 2016
Background: Chronic suppurative otitis media (CSOM) is the most common middle ear infection characterized by recurrent ear discharges or otorrhoea through a tympanic perforation from the middle ear. The organisms isolated from CSOM include both aerobic and anaerobic bacteria. Among the bacteria, Pseudomonas aeruginosa (P. aeruginosa) has been particularly blamed for deep seated and progressive destruction of middle ear and mastoid structures through its toxins and enzymes. The present study was done to determine the prevalence and antibiotic susceptibility of P. aeruginosa isolated from CSOM.Methods: This was a retrospective study conducted in a tertiary care hospital in South India in March 2016. Data was obtained from the microbiology records from January 2014 to January 2016. Patients who had active ear discharge for at least three months were included in the study. P. aeruginosa was identified by colony morphology, pigment production, characteristic musty or earthy ...
Otitis media (OM) is a multifactorial disease characterized by high rate of recurrence in young children and considered to cause hearing impairment in children. This study was undertaken to evaluate the antibacterial sensitivity of Gram-negative bacteria of OM to some antibiotics. A total of Fifty four (54) samples were obtained from patients with suspected cases of otitis media coming into the National Ear Care Centre for the first time. Fifty four (54) patients (29 male, 25 female), with mean ages of 3.86 and 3.29 respectively, tested positive to OM pathogens with a total of 84 bacterial isolates while no culturable pathogen was observed in 4 patients (7.4%). The study reveals highest frequency of Pseudomonas aeruginosa 60 (71.43 %) followed by Proteus mirabilis 14 (16.67), Klebsiella pnuemoniae 6 (7.14) and Escherichia coli 4 (4.76). P. aeruginosa had the highest prevalence among patients < 30 years, whereas K. pnuemoniae and E. coli had the least isolated across all age groups. Antimicrobial susceptibility test showed highest frequency of resistance among all isolates to amoxicillin, cotrimoxazole, nitrofurantoin and nalidixic acid. However, gentamicin, ofloxacin, augmentin and tetracycline were effective against Pseudomonas aeruginosa but ineffective against other isolates. Although antibiotics are the most preferred and prescribed drugs in incidents of OM, it is clear from this study that antimicrobial resistance still remains a persistent among bacterial pathogens of otitis media.
Journal of Ayub Medical College, Abbottabad : JAMC
Chronic suppurative otitis media (CSOM) is a prevailing and notorious infection in developing countries causing serious local damage and threatening complications. Early and effective treatment based on the knowledge of causing micro organisms and their sensitivity results in good clinical recovery and prevents from damage and complications. Pseudomonas aeruginosa is most common pathogen causing CSOM in Pakistan. The objective of this study is to identify incidence of Pseudomonas aeruginosa involved in CSOM and sensitivity against commonly prescribed antibiotics. A total of 263 patients with unilateral or bilateral chronic suppurative otitis media (CSOM) were enrolled in the study at Department of ENT, Karachi Medical and Dental College & Abbasi Shaheed Hospital, Karachi, Pakistan from December 2004 to May 2006. Sterile cotton swabs were used to collect pus from discharging ears and plated on Blood agar and MacConkey agar for 24 to 48 hours. Antibiotics susceptibility was tested by ...
IntroductIon Chronic suppurative otitis media (CSOM) is a chronic inflammation (infection) of the middle ear and mastoid cavity, which presents with recurrent ear discharges or otorrhoea through a persistent tympanic membrane perforation. [1] The disease usually begins in childhood as a spontaneous tympanic membrane perforation due to an acute infection of the middle ear, known as acute otitis media, or as sequelae of less severe forms of otitis media (e.g., secretory otitis media). In general, patients with tympanic membrane perforations that continue to discharge mucoid material for periods of 6 weeks to 3 months, despite medical treatment, are recognized as CSOM cases. [2] However, the World Health Organization (WHO) definition requires only 2 weeks of otorrhoea. [3] Using the country prevalence rates as grouped based on the WHO regional classification, Nigeria is among the countries with high prevalence (2%-4%) of CSOM in the world. [4] Moreover, otitis media is the most common ear disease in the tropics and in Nigeria in particular. [5-7] CSOM is the most common otologic condition seen across otorhinolaryngology clinics in Nigeria. [8-10] In CSOM, the bacteria may be aerobic (e.g., Pseudomonas aeruginosa [P. aeruginosa], Escherichia coli, Staphylococcus Background: Pseudomonas aeruginosa has been particularly blamed for the deep-seated and progressive destruction of the middle ear and mastoid structure through its toxins and enzymes. Drug-resistant P. aeruginosa has been found to increase along with its frequency. Aim: This study aimed to assess the antibiotic sensitivity pattern of P. aeruginosa and the effectiveness of ciprofloxacin in chronically discharging ears. Patients and Methods: This was a retrospective review of 180 patients who were managed for chronic suppurative otitis media between January 2009 and December 2018. Results: Out of the 180 patients, majority 67 (37%) were in the age group 1-10 years, range of 1 month to 70 years with mean age of 18 years and standard deviation of ± 16.8 years and M: F of 1.5:1. Most have had ear discharge for more than 6 months and the majority 78 (43.4%) of the patients had bilateral disease. Central tympanic membrane perforation was the predominant finding, 81 (45.0%) with a complication rate of 21.1%. Abscess formation was the most common complication seen among the patients. P. aeruginosa was the most common bacterial isolate, 43 (23.9%) followed by Staphylococcus aureus, 39 (21.7%). In the pediatric population, P. aeruginosa was most sensitive to levofloxacin, as opposed to gentamicin in the adult population. Ciprofloxacin was seen to be more effective in adults than in children. Resistance to ciprofloxacin was seen more in the children than in adults. There was a significant association between gender and occurrence of the organism. Conclusion: P. aeruginosa is most sensitive to levofloxacin and gentamicin in the pediatric and adult population, respectively. Resistance to ciprofloxacin is most common among adults.
African Journal of Microbiology Research, 2016
Otitis media (OM) is a multifactorial disease characterized by high rate of recurrence in young children and considered to cause hearing impairment in children. This study was undertaken to evaluate the antibacterial sensitivity of Gram-negative bacteria of OM to some antibiotics. A total of Fifty four (54) samples were obtained from patients with suspected cases of otitis media coming into the National Ear Care Centre for the first time. Fifty four (54) patients (29 male, 25 female), with mean ages of 3.86 and 3.29 respectively, tested positive to OM pathogens with a total of 84 bacterial isolates while no culturable pathogen was observed in 4 patients (7.4%). The study reveals highest frequency of Pseudomonas aeruginosa 60 (71.43 %) followed by Proteus mirabilis 14 (16.67), Klebsiella pnuemoniae 6 (7.14) and Escherichia coli 4 (4.76). P. aeruginosa had the highest prevalence among patients < 30 years, whereas K. pnuemoniae and E. coli had the least isolated across all age group...
Impact of multi drugs resistant bacteria on the pathogenesis of chronic suppurative otitis media
African Journal of Microbiology Research, 2010
One hundred twenty patients with chronic suppurative otitis media (CSOM) in Basrah, 65 (54.2%) males and 55 (45.8%) females, with male: females ratio (1.2:1) and 60 individual without otological problems as control group were included in this study, which done during the period between March 2009 and January 2010. This includes the collection of aural swab samples, culturing of samples, identification of causative agent’s species and antibiotic sensitivity. Gram’s negative bacteria were the commonest microorganism comprises (60%). Pseudomonas aeruginosa was common causative agent (19.04%), followed by Staphylococcus aureus (16.7%) andKlebsiella spp. (14.3%). Mixed infection was found in high percent (74%), in which P. aeruginosa and other microorganisms were more common. The antibiotic sensitivity pattern showed that P. aeruginosa was sensitive to Ciprofloxacin, amoxicillin +clavulanic acid and gentamicin, while other is appeared resistant, S. aureus was sensitive to ciprofloxacin, ...
Microbial Assessment of Chronic Suppurative Otitis Media in a Tertiary Care Center of Rajasthan
https://www.ijhsr.org/IJHSR\_Vol.7\_Issue.2\_Feb2017/IJHSR\_Abstract.019.html, 2017
Introduction: Chronic Suppurative Otitis Media (CSOM) is defined as infection of the middle ear that lasts for more than three months and is accompanied by otorrhoea and tympanic membrane perforation. Aims: Purpose of the study was to determine the prevalence of microbiological agents in CSOM, associated risk factors and establish antimicrobial resistance pattern of these microorganisms. Materials and Methods: The study was conducted after ethical approval by ethical committee in Department of Microbiology, Dr. S. N. Medical College, Jodhpur Rajasthan. Two pus swabs were collected with sterile cotton swabs from CSOM patients attending ENT OPD. Isolation, identification and characterization of bacterial isolate were done by standard phenotypic microbiological procedure. Observations & Results: Out of 150 cases 137(91.34%) was culture positive and 13 (8.66%) no growth (sterile) was obtained. Peak age of presentation was 11-20 years. Out of 150 cases 58% were males and 42% females. Most of these resides in rural area 53.3% and 46.7% belongs to urban area .Among the 150 cases 134 (89.3%) were unilateral while 16 (10.7%) bilateral CSOM patients. Out of total 78% patients already received antibiotic treatment while remaining 22% patients did not receive any treatment. Bacterial isolates were found to be present in 127 (92.7%) cases and rest 10 (7.3%) was Fungal was isolates. Pseudomonas aeruginosa showed highest resistance to Ceftazidime and least resistance to imipenem. Staphylococcus aureus showed highest resistance to Methicillin and least resistance to linezolid. Conclusion: The increasing rate Ceftazidime resistance and MRSA in our study is likely due to misuse of antibiotics and decrease concerns about infections caused by antibiotic resistant bacteria.
IP Innovative Publication Pvt. Ltd., 2018
Introduction: In the Otolaryngology Out Patient Department (OPD), Chronic Suppurative Otitis Media (CSOM) is the most common encountered otological disease. Staphylococcus aureus and Pseudomonas species are the most commonly encountered etiological agents. Untreated CSOM leads to complications such as facial nerve paralysis, lateral sinus thrombosis, labyrinthitis, meningitis and brain abscess. Materials and Methods: Patients with CSOM having unilateral or bilateral ear discharge for more than 3 months, attending Otolaryngology OPD or admitted in the wards were included in the study. Two swabs were collected from each patient with sterile precautions and submitted to the Microbiology Department. The samples were subjected to Gram’s stain and culture according to standard operative procedure. Antibiotic susceptibility testing was performed by Kirby-Bauer’s disc diffusion method as per CLSI guidelines. Results: A total of 520 samples were collected, out of which 474 samples showed growth. Staphylococcus aureus was the predominant isolate followed by Pseudomonas species. Staphylococcus isolates were highly sensitive to vancomycin and linezolid. Conclusion: Several studies have showed the predominance of different etiological agents in different geographical regions with different antibiotic sensitivity pattern. So, the knowledge of local etiological agent and its susceptibility pattern helps clinicians in treating the patients and to prevent its complications and drug resistance. Keywords: CSOM, Staphylococcus aureus, Pseudomonas aeruginosa, Antibiotic susceptibility pattern, Aerobic bacteria.
Antibiotics susceptibility of bacterial pathogens associated with otitis media
African Journal of Bacteriology Research, 2010
One hundred twenty patients with chronic suppurative otitis media (CSOM) in Basrah, 65(54.2%) males and 55(45.8%) Females, with male: females ratio (1.2:1) and 60 individual without ontological problems as control group were included in this study, which was done during the period of March, 2009 to January, 2010. This Include collection of aural swab samples, culturing of samples, identification of causative agents species and antibiotic sensitivity. Gram ' s negative bacteria were the commonest microorganisms; it comprises (60%). Pseudomonas aeruginosa was common causative agent (19.04%), followed by Staphylococcus aureus (16.7%) and Klebsiella spp. (14.3%). Mixed infection was found in high percent (74%), in which P. aeruginosa and other microorganisms were more common. The antibiotic sensitivity pattern showed that P. aeruginosa was sensitive to Ciprofloxacin, amoxicillin +clavulanic acid and gentamicin, while other is appeared resistant, S. aureus was sensitive to ciprofloxacin, amoxicillin+clavulanic acid, erthomycin, cephalexine and it is resistant to pencillin and ampicillin, klebsiella species were sensitive to ciprofloxacin, amoxicillin +clavulanic acid ,gentamicin,while resistant to tetracycline.