Study of eight medicinal plants for antioxidant activities (original) (raw)
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Screening of thirteen medicinal plant extracts for antioxidant activity
2010
Antioxidants are vital substances which possess the ability to protect the body from damage caused by free radical induced oxidative stress. A variety of free radical scavenging antioxidants exist within the body which many of them are derived from dietary sources like fruits, vegetables and teas. In this study the antioxidant activity and radical scavenging activity of methanolic extracts of selected plant materials, traditionally used by Iranian population as folk remedies was evaluated against linoleic acid peroxidation and 2,2diphenyl-1-picrylhydrazyl radical. The antioxidant activity expressed as IC 50 ranged from1.28 ng/ml in Biebresteinia multifida to 63.48 ng/ml in Polypodium vulgare. Radical scavenging activities expressed as IC 50 varied from 1.83 µg/ml in Salix sp. to 187.88 µg/ml in Allium hirtifolium.
Phytochemical Screening and Antioxidant Activity of some Egyptian Medicinal Plants
Journal of Modern Research
Extracts of three leaves: Cymbopogon citratus, Hibiscus sabdariffa, and Lawsonia inermis were screened for phytochemicals in ethanol (80%), hexane, and ethyl acetate. The potential of plant extracts to scavenge free radicals such as DPPH, ABTS and FRAP (Ferric Reducing Antioxidant Power) was investigated. For all extracts, phytochemical analysis indicated the presence of terpenoids, steroids, tannins, anthocyanins, phenols and flavonoids with absence of fatty acids in ethanol 80% and ethyl acetate. Ethyl acetate extract of L. inermis achieved a high percentage of TPC and TFC, but it was higher in 80% ethanol of H. sabdariffa than the other extracts under study. Ethyl acetate extracted the highest TPC (66.8 ± 3.6 mg/100g) in C. citratus and 80% ethanol extracted the highest TFC (37.23± 2.05mg/100g). Ethanolic extract (80%) of the three plants' leaves showed a higher IC 50 value than both ethyl acetate and hexane extracts. This indicates that 80% ethanol was the best solvent for extracting phenolic compounds and flavonoids. The "ABTS radical" scavenging activity was the highest for ethyl acetate extract of L. inermis. The lowest value was observed for hexane extract of both C. citratus and L. inermis. This study exhibited potential of ethanolic extracts (80%) of all plants for removing free radicals and their effectiveness to be a powerful antioxidant.
European Food Research and Technology, 2007
Since recent times, there is a growing interest in the food industry and in preventive health care for the development and evaluation of natural antioxidants from medicinal plant materials. In the present work we have investigated the antioxidant potency of phenolic compounds of 11 indigenous wild plant species from the Algerian Atlas commonly used in Arab folk medicine for a wide range of conditions. The antioxidant activity of each phenolic extracts has been assessed by using the Trolox Equivalent Antioxidant Capacity (TEAC) as a chemical test, and in a dynamic way by a biological assay based on whole blood resistance to free radical aggression. Of the 11 tested plants, 2 showed prominent antioxidant activity: Anthemis arvensis and Artemisia campestris. These plants had a very high level of Trolox equivalents and induced a strong delay of free radical-induced red blood cells hemolysis compared to antioxidant references. Artemisia campestris was the best inhibitor, its effect was far stronger than that of caffeic acid and was more than three times as high as ascorbic acid and two times higher than α-tocopherol efficiency. HPLC analysis showed a good correlation between the antioxidant activity and hydroxycinnamic derivatives. These preliminary results on the in vitro protection of blood against oxidative stress emphasized the benefit of the phenolic compounds of these medicinal plants. Our results enable us to proceed towards more detailed chemical and pharmacological understanding of these plant materials and show the interest A. Djeridane ( ) · of natural antioxidant in medicinal plants for the prevention of much free radical-mediated pathology.
Screening of antioxidant activity and phenolic content of 24 medicinal plant extracts
DARU Journal of Pharmaceutical …, 2008
Background: Antioxidants are vital substances which possess the ability to protect the body from damages caused by free radical-induced oxidative stress. A variety of free radical scavenging antioxidants are found in dietary sources like fruits, vegetables and tea. The purpose of this study was to evaluate the antioxidant activity of methanolic extracts of 24 selected plant materials (seeds or fruits), which are used by Iranian people as folk remedies and/or food supplements. Methods: The antioxidant activity was evaluated against linoleic acid peroxidation using 1,3-diethyl-2-thiobarbituric acid as reagent. At the same time the phenolic content of the extracts was determined using Folin-Ciocalteau reagent to evaluate their contribution to total antioxidant activity. Results: The antioxidant activity expressed as IC 50 ranged from 1.25 µg/ml in cucumber to 167.29 µg/ml in cardamom. Phenolic contents, expressed as gallic acid equivalents, varied from 21.76 mg/100g of the dried weight in linseed to 919.12 mg/100 g of the dried weight in Bishop's weed. No significant correlation was observed between antioxidant activity and phenolic content in the studied plant materials. Conclusion: The results of this study showed that there is no significant correlation between antioxidant activity and phenolic content of the studied plant materials and phenolic content could not be a good indicator of antioxidant capacity.
Oxidants and Antioxidants in Medical Science, 2014
Objective: Reactive oxygen has been implicated in degenerative diseases and medicinal activity of most herbs has been attributed to their ability to scavenge free radicals. Methods: Free radical scavenging and antioxidant activities of ethanolic extracts from the leaves of varieties of medicinal plants, namely Azadiratcha indica, Mangifera indica, Moringa oleifera, Psidium guajava, Terminalia catappa, Anacardiaceae occidentale, Cassia siamae, Chromolaena odorata, Telfaira occidentalis and Paraquetina nigresiens were evaluated. Reducing power, DPPH scavenging, hydroxyl radical scavenging and ferrous ion chelating activities, phenolic, flavonoid and vitamin C contents were determined. Results: C.siamae had excellent DPPH scavenging activity while P.guajava presented the lowest value. T.catappa had peak hydroxyl radical scavenging activity whereas T.occidentalis had the least capacity. C.siamae had the highest total phenolic and flavonoid contents while P.guajava and P.nigresiens showed the lowest phenol and flavonoid values. C.siamae also exhibited the highest reducing power activity whereas P.nigresiens had the least value. P.nigresiens had excellent ferrous iron chelating capacity while C.odorata had only poor activity. The total phenolic and flavonoid contents were highly correlated with the DPPH scavenging and reducing power activities, respectively. M.oleifera had the highest vitamin C content while P.guajava was the least.. Conclusion: Different values were obtained for each parameter for the medicinal leaves and free radical scavenging activity could be attributed to total phenolic and total flavonoid content. Among the plants tested, Cassia siamae leaf extract consistently exhibited the highest antioxidant activity and seems to be a promising source of natural antioxidants.
Study on the in vitro antioxidant properties of selected traditional medicinal plants
Journal of Pharmacognosy and Phytochemistry, 2020
Oxidative stress is the phenomenon by which the excessive production of free radicals and oxidants that cause detrimental effects to diseases and finally death. Plants are the rich source of antioxidants which have the potential to neutralize these reactive oxygen species,thereby preserving the redox equilibrium of the body. Western Ghats serves as anexcellent habitat for many endangered species of flora and a reservoir of edible source of food for many living beings. Some of the commonly available traditional plants like Ficus benghalensis, Psidium guajava, Beta vulgaris, Syzygium cumini were known to possess rich pharmacological properties. In the present study, we aim to evaluate and compare the in vitro antioxidant properties of the selected traditional medicinal plants using various radical scavenging and reducing capacity assays. Further, the structural elucidation of the presence of phytochemical compounds in the extract was carried out using Infrared (IR) spectra. The above investigation on the free radical scavenging properties and the determination of the functional groups of bioactive compounds may open up new interest on their applications in food, pharmaceutical and cosmetic industries.
Antioxidant activity and phenolic contents of 30 selected medicinal plants
2015
Plant aerial parts were tested for their free radical scavenging action by their interaction with 1,1diphenyl-2-picrylhydrazyl (DPPH) and total phenol. The results showed that the total phenolics varied significantly and ranged from 0.411 mg GAE/100 ml to 3.337 mg GAE/100 ml. The highest phenolic contents was determined in Aethionenmu devmonii. Antioxidant activity of plant extracts by the DPPH scavenger method (inhibition %) were found between 45.074% (Silene lephackola) to 81.527% (C.babylonica L.). It was concluded that the methanolic extracts of these widely consumed spices in Turkey are good sources of phenolic materials and have high antioxidative and free radical scavenging activities.
A comparative study on the antioxidant activity of selected medicinal plant extracts
European Journal of Biotechnology and Bioscience, 2016
The ethanol and methanol extracts of, Prunus dulkis (Almond), Ficus racemosa (Audumbar), Kalanchoe pinnata (Panphutti), Ocimum gratissimum (Tulsi) were screened for their free radical scavenging property using ascorbic acid as standard antioxidant. Free radical sacvanging activity was studied using DPPH method. Highest antioxidant activity observed in Kalanchoe pinnata with 69.841% and 78.56% in ethanol and methanol extract respectively. In case of ethanol extract Ficus racemosa, and Ocimum gratissimum showed higher antioxidant activity as compared to other. In case of methanol extract Kalanchoe pinnata is at top. This present study proves that the plant extracts have considerable antioxidant property and further detailed studies and characterization of these plant extracts can contribute to their medicinal and pharmaceutical applications.
2011
Antioxidants play an important role to protect the body from damage caused by free radical-induced oxidative stress. The antioxidant activities of 77 methanolic plant extracts were screened. This study is to submit some Egyptian plants to systematic antioxidant screening. The methanolic extracts of 77 plants were screened for their effect on 2, 2-Diphenyl-1-picryl-hydrazyl radical (DPPH) to determine their free radical scavenging activity. Extracts that gave 90% DPPH reduction or more were evaluated for total antioxidant, reducing power, superoxide anion radical scavenging, hydrogen peroxide scavenging and metal chelating activities. On subjecting the 77 methanolic extracts to DPPH, seven extract out of them gave 90% or more namely: Lycium europium L., Liomoniastrum monopetalum (L.) Boiss., Varthemia candicans (Delile) Boiss. Jasonia candicans (Delile) Botsch., Phlomis floccosa D. Don, Lavandula coronopifolia Poir., Thuja orientalis L. and Areca catechu L. Total antioxidant activity...
study on the antioxidant property of selected medicinal plants
The Clitoria ternatea, Solanum nigrum and Aloe vera leaves were extracted serially by the solvents of increasing polarity (petroleum ether, chloroform and ethanol) were tested for their free radical scavenging activity against DPPH. The petroleum ether extracts of Clitoria ternatea, Solanum nigrum and Aloe vera leaves were the most effective scavenging of DPPH. These plant extracts were also analyzed for the activities of selected enzymic antioxidants such as catalase, polyphenol oxidase and the non-enzymic antioxidants were ascorbic acid and total phenols. The results showed the leaves of Solanum nigrum possess higher levels of antioxidants.