Epigenetics of antigen-receptor gene assembly (original) (raw)
Ig gene rearrangement steps are initiated in early human precursor B cell subsets and correlate with specific transcription factor expression
Menno Van Zelm
The Journal of Immunology, 2006
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Control of immunoglobulin gene rearrangements in developing B cells
Shiaoching Gong
Current Opinion in Immunology, 1997
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Extensive Junctional Diversity in Ig Light Chain Genes from Early B Cell Progenitors of mMT Mice1
Laurent Bentolila
2000
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Pro-B cells sense productive immunoglobulin heavy chain rearrangement irrespective of polypeptide production
Paul C M van den Berk
Proceedings of the National Academy of Sciences, 2011
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Extensive Junctional Diversity in Ig Light Chain Genes from Early B Cell Progenitors of µMT Mice
Laurent Bentolila
The Journal of …, 1999
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Regulation of B cell fate commitment and immunoglobulin heavy-chain gene rearrangements by Ikaros
Karen L Reddy
Nature Immunology, 2008
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Rearrangement and Expression of Immunoglobulin Light Chain Genes Can Precede Heavy Chain Expression during Normal B Cell Development in Mice
Tatiana Novobrantseva
Journal of Experimental Medicine, 1999
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Regulation of immunoglobulin heavy-chain gene rearrangements
Ranjan Sen
Immunological Reviews, 2004
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B Cell Progenitors Are Arrested in Maturation but Have Intact VDJ Recombination in the Absence of Ig-α and Ig-β
Michael Reth
Journal of Immunology, 2002
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Adult B-cell repertoire is biased toward two heavy-chain variable-region genes that rearrange frequently in fetal pre-B cells
Ann Lawler
Proceedings of the National Academy of Sciences, 1987
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Immature surface Ig+ B cells can continue to rearrange kappa and lambda L chain gene loci
Ulf Grawunder
Journal of Experimental Medicine, 1993
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Immunoglobulin heavy chain expression shapes the B cell receptor repertoire in human B cell development
Henedina Antunes
Journal of Clinical Investigation, 2001
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Locus 'decontraction' and centromeric recruitment contribute to allelic exclusion of the immunoglobulin heavy-chain gene
Dolores Martinez
Nature Immunology, 2004
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Molecular Analysis of Human Immunoglobulin Heavy Chain Variable Genes (IgVH) in Normal and Malignant B Cells
Rizgar Mageed
The American Journal of Pathology, 1998
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a Murine B Cell Line Recombination Activating Gene-2 Expression Receptor-Mediated Down-Regulation of Secondary V ( D ) J Rearrangements and B Cell Haimovich
joseph haimovich
2000
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Surrogate Light Chain Expression Is Required to Establish Immunoglobulin Heavy Chain Allelic Exclusion during Early B Cell Development
Klaus Rajewsky
Immunity, 1996
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An Activation-Induced Cytidine Deaminase-Independent Mechanism of Secondary VH Gene Rearrangement in Preimmune Human B Cells
Nancy Longo
The Journal of Immunology, 2008
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Distinct mechanisms define murine B cell lineage immunoglobulin heavy chain (IgH) repertoires
Aaron Kantor
eLife, 2015
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Interallelic Class Switch Recombination Contributes Significantly to Class Switching in Mouse B Cells
Michel Cogné
The Journal of Immunology, 2005
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Control of Recombination Events During Lymphocyte Differentiation: Heavy Chain Variable Region Gene Assembly and Heavy Chain Class Switching
Pierre Ferrier
Annals of the New York Academy of Sciences, 1988
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Ig heavy chain protein controls B cell development by regulating germ-line transcription and retargeting V(D)J recombination
Mark Schlissel
The Journal of Immunology
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Human B-Cell Development
Cesar Nuñez
Annals of the New …, 1995
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Distinct roles for E12 and E47 in B cell specification and the sequential rearrangement of immunoglobulin light chain loci
Cornelis Murre
Journal of Experimental Medicine, 2009
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Transcriptional stalling in B-lymphocytes: A mechanism for antibody diversification and maintenance of genomic integrity
Jianbo Sun
Transcription, 2013
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Down-regulation of RAG1 and RAG2 gene expression in PreB cells after functional immunoglobulin heavy chain rearrangement
Ulf Grawunder
Immunity, 1995
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Single Germinal Centers Bearing Discrete Ig Chains in Chicken Oligoclonal Development of B Cells
Hiroshi Arakawa
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Rearrangement and expression of χ light chain genes can occur without μ heavy chain expression during differentiation of pre-B cells
Ulf Grawunder
International Immunology, 1993
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RAG-1 and ATM coordinate monoallelic recombination and nuclear positioning of immunoglobulin loci
Jane Skok
Nature Immunology, 2009
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Transient IL-7/IL-7R Signaling Provides a Mechanism for Feedback Inhibition of Immunoglobulin Heavy Chain Gene Rearrangements
Ranjan Sen
Immunity, 2003
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Author response: Distinct mechanisms define murine B cell lineage immunoglobulin heavy chain (IgH) repertoires
Aaron Kantor
2015
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V gene rearrangement is required to fully activate the hypermutation mechanism in B cells
Klaus Rajewsky
The Journal of Immunology
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Allelic 'choice' governs somatic hypermutation in vivo at the immunoglobulin κ-chain locus
Tatiana Novobrantseva
Nature Immunology, 2007
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The E Enhancer Region Influences H Chain Expression and B Cell Fate without Impacting IgVH Repertoire and Immune Response In Vivo
Michel Cogné
The Journal of Immunology, 2014
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Influence of immunoglobulin heavy- and light-chain expression on B-cell differentiation
Rusty Lansford
Genes & Development, 1994
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A Novel Mechanism for B Cell Repertoire Maturation Based on Response by B Cell Precursors to Pre-B Receptor Assembly
Condie Carmack
Journal of Experimental Medicine, 1998
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