Ribozymes: recent advances in the development of RNA tools (original) (raw)

Ribozymes: the characteristics and properties of catalytic RNAs

Kyle Tanner

FEMS Microbiology Reviews, 1999

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The new world of ribozymes

Luc Jaeger

Current Opinion in Structural Biology, 1997

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Modulating RNA structure and catalysis: lessons from small cleaving ribozymes

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Cellular and Molecular Life Sciences, 2009

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Nuclease-resistant synthetic ribozymes: developing a new class of therapeutics

Nassim Usman

Journal of Clinical Investigation, 2000

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Thirty-five years of research into ribozymes and nucleic acid catalysis: where do we stand today?

Bettina Appel

F1000Research, 2016

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Efficient new ribozyme mimics: direct mapping of molecular design principles from small molecules to macromolecular, biomimetic catalysts

Andrew Daniher, James Bashkin

Nucleic Acids Research, 2001

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A structural analysis of in vitro catalytic activities of hammerhead ribozymes

Erasmus Schneider

BMC Bioinformatics, 2007

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Chemically Modified Hammerhead Ribozymes with Improved Catalytic Rates

Nassim Usman

Biochemistry, 1996

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Ribozymes: catalytic RNAs that cut things, make things, and do odd and useful jobs

Nils Walter

Biologist, 2002

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Substrate specificity and reaction kinetics of an X-motif ribozyme

Dennis Lazarev

RNA, 2003

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Chimeric DNA-RNA hammerhead ribozymes have enhancedin vitrocatalytic efficiency and increased stabilityin vivo

Piotr Swiderski

Nucleic Acids Research, 1992

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Selection, design, and characterization of a new potentially therapeutic ribozyme

Leonid Beigelman

RNA, 2002

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Chemical Modification of Hammerhead Ribozymes

David Sweedler

Journal of biological …, 1995

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Synthetic Hammerhead Ribozymes as Tools in Gene Expression

Staale Lyngstadaas

Critical Reviews in Oral Biology & Medicine, 2001

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Ribozyme mimics as catalytic antisense reagents

James Bashkin

Applied Biochemistry and Biotechnology, 1995

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Identification and characterization of a short 2'-3' bond-forming ribozyme

Monika Konarska

RNA, 2008

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Optimizing the Cell Efficacy of Synthetic Ribozymes

Nassim Usman

Journal of Biological Chemistry, 1996

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A ribozyme that ligates RNA to protein

Scott Baskerville

Proceedings of the National Academy of Sciences of the United States of America, 2002

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Structural Features of Target RNA Molecules Greatly Modulate the Cleavage Efficiency of trans-Acting Delta Ribozymes

Mariola Dutkiewicz

Biochemistry, 2007

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Ribozymes as therapeutic tools for genetic disease

Leonidas Phylactou

Human Molecular Genetics, 1998

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An oligodeoxyribonucleotide that supports catalytic activity in the hammerhead ribozyme domain

Pascal Chartrand

Nucleic Acids Research, 1995

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Capturing Hammerhead Ribozyme Structures in Action by Modulating General Base Catalysis

Young-In Chi

PLoS Biology, 2008

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Ribozyme Catalysis Revisited: Is Water Involved?

Nils Walter

Molecular Cell, 2007

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A small nucleolar RNA:ribozyme hybrid cleaves a nucleolar RNA target in vivo with near-perfect efficiency

Dmitry Samarsky

Proceedings of the National Academy of Sciences, 1999

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Insights into functional modulation of catalytic RNA activity

Denis Drainas

IUBMB Life, 2008

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Faculty of 1000 evaluation for Capturing hammerhead ribozyme structures in action by modulating general base catalysis

Pascale Legault

F1000 - Post-publication peer review of the biomedical literature, 2008

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New strategy for the synthesis of chemically modified RNA constructs exemplified by hairpin and hammerhead ribozymes

Tom Brown

2010

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In vitro selection of active hairpin ribozymes by sequential RNA-catalyzed cleavage and ligation reactions

John Burke

Genes & Development, 1992

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Structural basis for heterogeneous kinetics: Reengineering the hairpin ribozyme

Nils Walter

Proceedings of the National Academy of Sciences, 1998

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Modulation of Catalytic RNA Biological Activity by Small Molecule Effectors

Dimitra Kalavrizioti

Mini-Reviews in Medicinal Chemistry, 2006

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