Ras signalling and apoptosis (original) (raw)

Cell Signaling: Life or Death Decisions of Ras Proteins

Rachel Buchsbaum

Current Biology, 2002

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The dark side of Ras: regulation of apoptosis

Channing Der

Oncogene, 2003

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Significance of Ras Signaling in Cancer and Strategies for its Control

Arun B Gurung

Oncology & Hematology Review (US), 2015

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Death pathways triggered by activated Ras in cancer cells

J. Meyer, William Maltese

Frontiers in Bioscience, 2011

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Inactivation of Ras GTPase-activating proteins promotes unrestrained activity of wild-type Ras in human liver cancer

Diego Calvisi

Journal of Hepatology, 2011

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Approaches to Ras signaling modulation and treatment of Ras-dependent disorders: a patent review (2007 – present)

Elena Sacco

Expert Opinion on Therapeutic Patents, 2012

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Targeting RAS signalling pathways in cancer therapy

Julian Downward

Nature Reviews Cancer, 2003

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Differential Regulation of RasGAPs in Cancer

Carlos Enrich

Genes & Cancer, 2011

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Distinct functions for Ras GTPases in the control of proliferation and apoptosis in mouse and human mesangial cells

Bruce Hendry

Kidney International, 2006

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Ras proteins: paradigms for compartmentalised and isoform-specific signalling

Ian Prior

Cellular and Molecular Life Sciences, 2007

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Ras family genes: An interesting link between cell cycle and cancer

Giulia Russo

Journal of Cellular Physiology, 2002

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Ras family signaling: therapeutic targeting

Adrienne Cox

Cancer biology & therapy

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Genetic analysis of Ras signalling pathways in cell proliferation, migration and survival

Jelena Urosevic, Eugenio Santos

The EMBO Journal, 2010

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RAS Proteins and Their Regulators in Human Disease

Dwight Nissley

Cell, 2017

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Signal transduction. Prelude to an anniversary for the RAS oncogene

Julian Downward

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M-Ras/R-Ras3, a Transforming Ras Protein Regulated by Sos1, GRF1, and p120 Ras GTPase-activating Protein, Interacts with the Putative Ras Effector AF6

Lawrence Quilliam

Journal of Biological Chemistry, 1999

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R-Ras is regulated by activators and effectors distinct from those that control Ras function

Lawrence Quilliam

Oncogene, 1997

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Regulation of RAS oncogenicity by acetylation

Robert Spang

Proceedings of the National Academy of Sciences, 2012

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Ras oncogenes and their downstream targets

Stefan Albert

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2007

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Identification of a Novel Ras-Regulated Proapoptotic Pathway

Joseph Avruch

Current Biology, 2002

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Positive autoregulation of ras genes expression in fibroblasts

T. Thomson

FEBS Letters, 1997

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Epigenetic silencing of a Ca2+-regulated Ras GTPase-activating protein RASAL defines a new mechanism of Ras activation in human cancers

Ada Wong

Proceedings of The National Academy of Sciences, 2007

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Ras isoform abundance and signalling in human cancer cell lines

Ian Prior

Oncogene, 2008

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RAS and PKA pathways in cancer: new insight from transcriptional analysis

Daniela Gaglio, Ferdinando Chiaradonna

Frontiers in Bioscience, 2008

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Cancer Targets in the Ras Pathway

Frank McCormick, Katsutoshi Oda

Cold Spring Harbor Symposia on Quantitative Biology, 2005

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Signal transduction by Ras-like GTPases: a potential target for anticancer drugs

Marcel Spaargaren

Gene expression, 1995

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New druggable targets in the Ras pathway?

David Matallanas

Current Opinion in Molecular Therapeutics, 2010

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Ras and phosphoinositide 3-kinase: partners in development and tumorigenesis

Julian Downward

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Ras and Ras mutations in cancer

Thiagarajan Raman

Central European Journal of Biology, 2013

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Genetic and pharmacologic dissection of Ras effector utilization in oncogenesis

Channing Der

Methods in enzymology, 2006

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Distinct requirements for Ras oncogenesis in human versus mouse cells

Channing Der

Genes & Development, 2002

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