Metabolism of bupropion by baboon hepatic and placental microsomes (original) (raw)

Deeper Insight into the Reducing Biotransformation of Bupropion in the Human Liver

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Drug Metabolism and Pharmacokinetics, 2014

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Bupropion metabolism by human placenta

Gary Hankins

Biochemical Pharmacology, 2010

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Comparison of In Vitro Stereoselective Metabolism of Bupropion in Human, Monkey, Rat, and Mouse Liver Microsomes

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Evaluation of the Contribution of Cytochrome P450 3A4 to Human Liver Microsomal Bupropion Hydroxylation

Stacy Shord

Drug Metabolism and Disposition, 2001

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Transplacental transfer and metabolism of bupropion

Gary Hankins

Journal of Maternal-fetal & Neonatal Medicine, 2009

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Metabolism and disposition of bupropion in pregnant baboons (Papio cynocephalus)

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Drug metabolism and disposition: the biological fate of chemicals, 2014

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Role of transporter-mediated efflux in the placental biodisposition of bupropion and its metabolite, OH-bupropion

Gary Hankins

Biochemical Pharmacology, 2010

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Formation of Threohydrobupropion from Bupropion Is Dependent on 11 -Hydroxysteroid Dehydrogenase 1

Daniela Schuster

Drug Metabolism and Disposition, 2013

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Bupropion Hydroxylation as a Selective Marker of Rat CYP2B1 Catalytic Activity

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Simultaneous quantitative determination of bupropion and its three major metabolites in human umbilical cord plasma and placental tissue using high-performance liquid chromatography–tandem mass spectrometry

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Journal of Pharmaceutical and Biomedical Analysis, 2012

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Mechanistic Approach for Toxic Effects of Bupropion in Primary Rat Hepatocytes

Aziz Eftekhari

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Effect of hepatic and renal dysfunction on disposition of Bupropion in rats

Musbah Tanira

European Journal of Drug Metabolism and Pharmacokinetics, 1988

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Developmental Expression of CYP2B6: A Comprehensive Analysis of mRNA Expression, Protein Content and Bupropion Hydroxylase Activity and the Impact of Genetic Variation

A. Gaedigk

Drug metabolism and disposition: the biological fate of chemicals, 2015

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Cytochrome P450 3A-MEDIATED Metabolism of Buspirone in Human Liver Microsomes

Humberto Jimenez

Drug Metabolism and Disposition, 2005

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Ultra-Performance Liquid Chromatography-Tandem Mass Spectrometry Method for the Determination of Bupropion and its Main Metabolites in Human Whole Blood

brasil friends

Journal of Analytical Toxicology, 2010

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The Influence of Sex, Ethnicity, and CYP2B6 Genotype on Bupropion Metabolism as an Index of Hepatic CYP2B6 Activity in Humans

Erin Schuetz

Drug Metabolism and Disposition, 2013

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Transplacental Transfer and Metabolism of Buprenorphine in Preterm Human Placenta

Gary Hankins

American Journal of Perinatology, 2011

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A simple and sensitive LC–ESI-MS (ion trap) method for the determination of bupropion and its major metabolite, hydroxybupropion in rat plasma and brain microdialysates

Neşe Tunçel

Talanta, 2011

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High-throughput liquid chromatography–tandem mass spectrometry determination of bupropion and its metabolites in human, mouse and rat plasma using a monolithic column

Eric Yang

Journal of Chromatography B-analytical Technologies in The Biomedical and Life Sciences, 2004

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Sensitive, selective and rapid determination of bupropion and its major active metabolite, hydroxybupropion, in human plasma by LC-MS/MS: application to a bioequivalence study in healthy Indian subjects

MANISH YADAV

Biomedical Chromatography, 2011

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Influence of CYP2B6 genetic variants on plasma and urine concentrations of bupropion and metabolites at steady state

Rachel Tyndale

Pharmacogenetics and Genomics, 2013

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Stereoselective analysis of hydroxybupropion and application to drug interaction studies

Andrew McLachlan

Chirality, 2007

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Convulsive liability of bupropion hydrochloride metabolites in Swiss albino mice

Louis Mcmahon

Annals of General Psychiatry, 2008

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Disposition of Bupivacaine and Its Metabolites in the Maternal, Placental, and Fetal Compartments in Rats

Raymond Suckow

Anesthesiology, 2000

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CYP2B6 and Bupropion’s Smoking-Cessation Pharmacology: The Role of Hydroxybupropion

Babalola Faseru

2012

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