Interleukin 2 abrogates the nonresponsive state of T cells expressing a forbidden T cell receptor repertoire and induces autoimmune disease in neonatally thymectomized mice (original ) (raw )Premature escape of double-positive thymocytes to the periphery of young mice. Possible role in autoimmunity
Adriana Bonomo
The Journal of Immunology
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Early events in the thymus affect the balance of effector and regulatory T cells
Adrian Hayday
Nature, 2006
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T-cell development in the absence of a thymus: the number, the phenotype, and the functional capacity of T lymphocytes in nude mice
Margot Skinner
The American journal of anatomy, 1984
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The mechanism of reduction of cell-mediated cytotoxicity in neonatally thymectomized mice
Hideyuki Kawauchi
Immunology
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Thymus-Dependent Areas in the Lymphoid Organs of Neonatally Thymectomized Mice
maria sousa
Journal of Experimental Medicine, 1966
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Responsiveness of fetal and adult CD4-, CD8- thymocytes to T cell activation
William Gause
The Journal of Immunology
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Recent thymic emigrants are the preferential precursors of regulatory T cells differentiated in the periphery
Jocelyne Demengeot
Proceedings of the National Academy of Sciences, 2013
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A Murine Early Thymocyte Developmental Sequence is Marked by Transient Expression of the Interleukin 2 Receptor
Anne Wilson
Proceedings of The National Academy of Sciences, 1989
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Post-thymic maturation: young T cells assert their individuality
Deborah Hendricks
Nature Reviews Immunology, 2011
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Peripheral but not thymic T cells participate in an autoreactive T cell network
Marc Weksler
Cellular Immunology, 1988
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Postnatal disappearance of self-reactive (V beta 6+) cells from the thymus of Mlsa mice. Implications for T cell development and autoimmunity
Reto Schneider
Journal of Experimental Medicine, 1989
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Susceptibility of neonatal T cells and adult thymocytes to peripheral tolerance to allogeneic stimuli
Alberto Nobrega
Immunology, 2008
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Sequential appearance of host-derived T cell subsets during differentiation in nude mice grafted with rat fetal thymus
Yasunobu Yoshikai
Journal of Immunology, 1990
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Neonatal thymectomy reveals differentiation and plasticity within human naive T cells
Theo Van Den Broek
The Journal of clinical investigation, 2016
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Thymus-independent development and negative selection of T cells expressing T cell receptor alpha/beta in the intestinal epithelium: evidence for distinct circulation patterns of gut- and thymus-derived T lymphocytes
Michael Julius
Journal of Experimental Medicine, 1992
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Peripheral regulatory T lymphocytes recirculating to the thymus suppress the development of their precursors
Véronique Adoue
Nature Immunology, 2015
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Neonatal castration affects intrathymic kinetics of T-cell differentiation and the spleen T-cell level
Nevena Arsenovic-Ranin
Journal of Endocrinology, 2007
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Developmental ages of the thymic epithelium and of the T cell precursors together determine the proportions of peripheral CD4+ cells
Kara Hamilton
Journal of immunology (Baltimore, Md. : 1950), 1994
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Development of T cells in SCID mice grafted with fetal thymus from AKR mice or F344 rats
Robert Good
European Journal of Immunology, 1993
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Origin, phenotype and autoimmune potential of T cells in human immune system mice receiving neonatal human thymus tissue
Megan Sykes
Frontiers in Immunology
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Intoxication of high affinity IL-2 receptor positive thymocytes blocks early stages of T cell maturation
Wlodzimierz Maslinski
International Immunology, 1992
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Delayed functional maturation of natural regulatory T cells in the medulla of postnatal thymus: role of TSLP
Geoffry Knudsen
BMC immunology, 2006
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Thymocyte Activation and Death: a Mechanism for Molding the T Cell Repertoire
Mladen Mercep
Annals of the New York Academy of Sciences, 1991
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Intrathymic lymphoid precursor cells during fetal thymus development
Mariastefania Antica
The Journal of Immunology
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Absence of the Lyt-2-,L3T4+ lineage of T cells in mice treated neonatally with anti-I-A correlates with absence of intrathymic I-A-bearing antigen-presenting cell function
Dan Longo
Journal of Experimental Medicine
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Thymic and Extrathymic T Cell Development Pathways Follow Different Rules
Rafik Terra
The Journal of Immunology, 2002
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The thymus has two functionally distinct populations of immature αβ+ T cells: One population is deleted by ligation of αβTCR
Willi Born
Cell, 1989
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Human neonatal thymectomy induces altered B-cell responses and autoreactivity
Rachel Sorek
European Journal of Immunology
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Precocious expression of T cell functional response genes in vivo in primitive thymocytes before T lineage commitment
Ellen Rothenberg
International Immunology, 1998
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Cutting Edge: Autoimmune Disease in Day 3 Thymectomized Mice Is Actively Controlled by Endogenous Disease-Specific Regulatory T Cells
Randall Roper
The Journal of Immunology, 2008
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The Thymic Niche Does Not Limit Development of the Naturally Diverse Population of Mouse Regulatory T Lymphocytes
Paola Romagnoli
The Journal of Immunology, 2012
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Characterization of the progeny of pre-T cells maintained in Vitro by IL-3: Expression of the IL-2 receptor and CD3 during thymic development
Deborah Dempsey
Cellular Immunology, 1991
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Proliferation of phenotypically immature human thymocytes with and without interleukin 2 receptors
franco oreste ranelletti
Journal of immunology (Baltimore, Md. : 1950), 1986
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An Opposite Pattern of Selection of a Single T Cell Antigen Receptor in the Thymus and among Intraepithelial Lymphocytes
Wills Hetzel
2010
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Histochemical and molecular overview of the thymus as site for T-cells development
F. Bonomini
Progress in Histochemistry and Cytochemistry, 2008
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