Role of thymidine in biochemical modulation: a review (original) (raw)
Cytotoxic and biochemical effects of thymidine and 3-deazauridine on human tumor cells
John Francis Mendoza
Cancer research, 1984
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Perturbation of thymidine kinase regulation: A novel chemotherapeutic approach
Miguel A . Vazquez Padua
Advances in Enzyme Regulation, 1986
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Schedule-dependent antitumor and toxic effects of thymidine and 5-fluorouracil in AKR and L1210 leukemias
Fred Valeriote
Cancer Chemotherapy and Pharmacology, 1986
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Comparative studies of chemotherapy of human tumor cells in vitro by tritiated thymidine uptake inhibition and soft agar clonogenic assay
Helene Hill
Journal of Surgical Oncology, 1986
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Modulation of thymidine phosphorylase by neoadjuvant chemotherapy in primary breast cancer
Shigeaki Ohno
British Journal of Cancer, 2004
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Thymidylate synthetase inhibition in malignant tumors and normal liver of patients given intravenous 5-fluorouracil
Colin Paul Spears
Cancer Research
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Thymidylate synthase and drug resistance
Herbert Pinedo
European Journal of Cancer, 1995
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Effect of very high-dose thymidine infusions on leukemia and lymphoma patients
Ting-Chao Chou
Cancer research, 1984
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Methotrexate di-n-butyl ester effects on thymidine metabolism
Andre Rosowsky
Biochemical Pharmacology, 1979
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Immunohistochemical characterization of pyrimidine synthetic enzymes, thymidine kinase-1 and thymidylate synthase, in various types of cancer
Shingo Kamoshida
Oncology Reports, 2010
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Expression of Thymidine Phosphorylase and Dihydropyrimidine Dehydrogenase in Human Breast Carcinoma Cells and Tissues
Noriaki Ohuchi
Anticancer Research, 2009
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Thymidine kinase, thymidylate synthase, and dihydropyrimidine dehydrogenase profiles of cell lines of the National Cancer Institute's Anticancer Drug Screen
Lauren Young
Clinical cancer research : an official journal of the American Association for Cancer Research, 2001
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Pharmacokinetics and organ distribution of N -methanocarbathymidine, a novel thymidine analog, in mice bearing tumors transduced with the herpes simplex thymidine kinase gene
Riad Agbaria
Cancer Chemotherapy and Pharmacology, 2002
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Modulation of RTX cytotoxicity by thymidine and dipyridamole in vitro: implications for chemotherapy
Norman Lehman
Cancer Chemotherapy and Pharmacology, 2000
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Developments of the fluoropyrimidines as inhibitors of thymidylate synthetase: pharmacologic and clinical aspects
David Machover
Journal of surgical oncology, 1991
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Thymidine as a kinetic and biochemical modulator of 1-beta-D-arabinofuranosylcytosine in human acute nonlymphocytic leukemia
Ting-Chao Chou
Cancer research, 1984
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Elevation of thymidylate synthase following 5-fluorouracil treatment is prevented by the addition of leucovorin in murine colon tumors
Herbert Pinedo
Cancer research, 1992
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The role of thymidylate synthase in cellular regulation
Carmen Allegra
Advances in Enzyme Regulation, 1996
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Cytotoxicity of Antifolate Inhibitors of Thymidylate and Purine Synthesis to WiDr Colonic Carcinoma Cells
Norman Lehman
Cancer Research, 1993
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Chuang RY, Chuang LF, Kawahata RT, Israel MEffect of N-trifluoroacetyladriamycin-14-valerate on [3H]thymidine uptake and DNA synthesis of human lymphoma cells. J Biol Chem 258:1062-1065
Mervyn Israel
Journal of Biological Chemistry
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Significance of thymidylate synthase activity in renal cell carcinoma
Tsuneharu Miki
Clinical cancer research : an official journal of the American Association for Cancer Research, 2003
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Altered deoxyuridine and thymidine in plasma following capecitabine treatment in colorectal cancer patients
Kong Li
British Journal of Clinical Pharmacology, 2007
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The dual role of thymidine phosphorylase in cancer development and chemotherapy
Federico Gago
Medicinal Research Reviews, 2009
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Carbon-11-thymidine and FDG to measure therapy response
Thomas Lewellen
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1998
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Thymidine Phosphorylase: A Two-Face Janus in Anticancer Chemotherapy
Federico Focher
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Dipyridamole inhibits reversion by thymidine of methotrexate effect and increases drug uptake in Sarcoma 180 cells
Jose Mordoh, Laura Bover
Proceedings of the National Academy of Sciences of the United States of America, 1984
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3'-Deoxy-3'-[(18)F]Fluorothymidine Uptake Is Related to Thymidine Phosphorylase Expression in Various Experimental Tumor Models
John Griffiths
Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging, 2017
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Interaction of 5-fluoro-4-thio-2′-deoxyuridine 5′-phosphate with mammalian tumour thymidylate synthase: Role of the pyrimidine N(3)-H dissociation
Joanna Ciesla
Biochemical and Biophysical Research Communications, 1987
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Effect of 3‘-Azido-3’-deoxythymidine on 5-Fluorouracil Metabolism in Human Promyelocyte Leukaemia HL-60 Cells
Thomas Szekeres
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Mechanisms of innate resistance to thymidylate synthase inhibition after 5-Fluorouracil
Colin Paul Spears
Cancer Research
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The biochemical pharmacology of the thymidylate synthase inhibitor, 2-desamino-2-methyl-N10-propargyl-5,8-dideazafolic acid (ICI 198583)
Joel Bishop
Biochemical Pharmacology, 1991
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Basis of FLT as a cell proliferation marker: comparative uptake studies with [3H]thymidine and [3H]arabinothymidine, and cell-analysis in 22 asynchronously growing tumor cell lines
Jun Toyohara
Nuclear Medicine and Biology, 2002
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Selective assays for thymidine kinase 1 and 2 and deoxycytidine kinase and their activities in extracts from human cells and tissues
T. Spasokoukotskaja
Biochemical and Biophysical Research Communications, 1992
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The relationship between endogenous thymidine concentrations and [18F]FLT uptake in a range of preclinical tumour models
Dmitry Soloviev
EJNMMI Research, 2016
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Toxicologic effects of a high dose of thymidine in mice
Bach Ardalan
Toxicology and Applied Pharmacology, 1980
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