A clinicomycological study of dermatophytic infection in a tertiary care hospital (original) (raw)

Current trends of Clinicomycological Profile of Dermatophytosis in Central India

Abstract: Background: Dermatophytosis is one of the most common cutaneous fungal infections of public health importance. Its prevalence differs from place to place and is influenced by environmental conditions, personal hygiene and habits. Aim: The present study was undertaken to assess the clinical and mycological profile of dermatophytic infection and identify the species of fungi using standard techniques. Materials and methods: A cross sectional study was conducted in 100 clinically diagnosed patients of dermatophytosis attending the dermatology outpatient department of our hospital. Proforma containing structured questionnaire was also filled. Skin scrapings, nail scrapes or nail clippings and infected hair stubs were collected. All specimens were screened for dermatophytes by direct microscopy using KOH DMSO preparation and confirmed by fungal culture. Results: Tinea unguium (52.0%) was predominant clinical condition. Males were affected more (79.0%) than females. Dermatophytosis was predominantly found in more than 60 years (32.0%) and 31-45 years (24.0%). Fungi were demonstrated in 55.0% cases by KOH mount and 46.0% cases were positive by culture. 16.0% cases were KOH negative and culture positive. Trichophyton rubrum (41.0%) was the predominant species. Conclusions: Males with age group above 60 years were most commonly affected in our area. Predominant clinical type was tinea unguium probably because most of them were farmers and labourers with poor hygiene. Trichophyton rubrum was the commonest dermatophyte isolated. KOH negative and culture positive cases indicate that culture is a gold standard for isolation and identification of dermatophytes. Key words: Dermatophyte, Dermatophytosis, Tinea, Trichophyton

Trichophyton rubrum the predominant etiological agent in human dermatophytoses in Chennai, India

African Journal of Microbiology Research, 2007

The present study was undertaken to find the predominant etiological agent of dermatophytoses among the patients attending the out patient clinic of Mycology Section, Department of Dermatology, Madras Medical College and Hospital, Chennai. Specimens were collected from suspected patients with dermatophytoses and examined for the presence of fungal elements, cultured, isolated and identified. Among the 90 suspected patients with clinical symptoms of dermatophytoses, 71 (78.9%) were confirmed in culture. Trichophyton genus was accounted for 93% of dermatophytoses, which was shared by Trichophyton rubrum (73.3%) andTrichophyton mentagrophytes (19.7%), followed by Epidermophyton floccosum (4.2%) and Microsporum gypseum (2.8%). It was noted that tinea corporis (64.8%) is the most prevalent infection followed by tinea cruris (26.8%), tinea pedis (5.6%) and onychomycoses (2.8%). T. rubrum was the predominant species responsible for the dermatophytoses, especially tinea corporis in Chennai,...

Epidemiological Study Of Dermatophytosis In Okara, Pakistan

2016

A clinical study was carried out among patients with tinea infections in Okara during the year 2013-2014 with respect to age, gender and clinical presentation of the infection. A total number of 150 samples were collected from tinea infected patients out of which only 120 were found positive for Trichophyton spp and Microsporum spp and no Epidermophyton was observed. Among positive cases Trichophyton spp was most dominant (68.3%) followed by Microsporum spp. (38%). The most effected age group was 0-10 years (40.8%). Male patients were infected more as compared to females and male to female ratio among positive cases was observed as 17:13. Rural community was observed to be most affected by the dermatophyte fungus. This study manifests the importance of correct mycological diagnosis for effective disease management.

Current mycological profile of dermatophytosis in a tertiary care set up in North Bengal

Journal of Pakistan Association of Dermatology, 2016

Objective To determine the occurrence, distribution & mycological profile of dermatophytosis in North Bengal Medical College and Hospital, in Darjeeling, West Bengal, India. Methods A total of 200 specimens were collected from clinically suspected dermatophytoses from February to April 2013. Samples of skin scrapings, hair shafts and nails were sent to laboratory from dermatology OPD for direct examination, fungal culture and identification. Results Adult males outnumbered females in all cases of dermatophytosis except tinea corporis. Most cases showed high culture sensitivity except tinea unguium. Trichophyton rubrum was the most commonly isolated fungal organism. Conclusion This study identifies the clinical distribution and predominant organisms causing dermatophytosis in North Bengal, which may be useful to ascertain the past and present trends in dermatophytosis and provide insight into future diagnosis and treatment.

Extensive tinea corporis and tinea cruris et corporis due to trichophyton interdigitale

Journal of Dermatology & Cosmetology, 2019

Background: India is facing a gruesome epidemic-like scenario of chronic, extensive and recalcitrant dermatophytosis for the past 5-6 years. Dermatophytosis, also commonly known as tinea, used to be considered as trivial infection and was easy to treat. Unethical and irrational mixing of antibacterial and topical corticosteroid with antifungal agents has been instrumental for this extremely challenging situation. Applying such topical preparations for the treatment of dermatophytosis, without any oral antifungal agents can result in extensive lesions and also, fungal resistance. Objective: To find out the cause and dermatophyte species associated with the extensive lesions of tinea corporis. Patients and methods: A study was carried out in the tertiary care centre by the Department of Dermatology and Microbiology during the period starting from October 2016 to April 2017. A total of 158 patients were consented. Any patient with clinical findings of Tinea corporis and KOH and/or cult...

A preliminary clinico-mycological study of dermatophytes infection

International Journal of Research in Medical Sciences

Background: Superficial fungal infections are the most common skin diseases, affecting millions of people throughout the world. Aim of the study was carried out to find, the effect of seasonal variation and socio-economic status on the prevalence of dermatophytes.Methods: A total of fifty clinically suspected cases of dermatophytosis were subjected to mycological studies.Results: Out of which 32 (64%) were culture positive Tinea corporis was the most common clinical type followed by Tinea cruris. Tricophoton rubrum 17/32 (53.12%) was the most common isolate followed by T. mentagrophytes 9/32(28.12%), T. tonsurans 3/32(9.37%), T. verrrucosum 2/32(6.25%) and T. schoenleinii 1/32(3.12%). Most of the patients belonged to the middle socio-economic group (28/50) followed by lower socio-economic group (19/50) maximum cases of dermatophytosis were reported from June to August revealing the fact that hot and humid weather during the monsoons has a great impact on the occurrence of dermatophy...

“Clinicomycological Study of Dermatophytosis At Tertiary Care Hospital In Bhavnagar, Gujarat”

Dermatophytes are the Infection of the skin, hair or nails caused by a group of keratinophilic fungi, called dermatophytes, also known as Tinea or ring worm.The study aimed to find Clinico-Mycological correlation of dermatophytosis and to find out various species of dermatophytes prevalent in & around Bhavnagar city. Materials and Methods: Skin, hair and nail samples from 600 clinically suspected cases of dermatophytosis were screened by direct microscopic examination using 10% potassium hydroxide (KOH) mount and inoculated for culture in Sabouraud dextrose agar (SDA) and dermatophyte test medium (DTM).

Epidemiological studies on Dermatophytosis in human patients in Himachal Pradesh, India

2014

Dermatophytes are among the common fungal agents implicated in superficial skin infections worldwide. They include species of Trichophyton, Microsporum and Epidermophyton. In hot and humid climates of tropical and subtropical regions, the incidence of these pathogens is higher. We present in this article, the epidemiological data regarding the prevalence of different dermatophyte species involved in superficial mycoses in human patients in the state of Himachal Pradesh (India) and different clinical conditions, age and sex of the patients. A total of 202 samples in the form of skin and nail scrapings, hair follicles were collected from different ringworm/tinea conditions which included: Tinea corporis, T. capitis, T. cruris, T. pedis, T. unguium, T. faciei, T. manuum and T. gladiatorum. On culturing, 74 samples (36.6%) were found positive for dermatophyte spp. Trichophyton spp. was the predominant one (98.65% cases) followed by Microsporum gypseum (1.35% cases). However, we did not ...

Mycological profile of dermatophytosis in patient attending a tertiary care hospital

International Journal of Applied Research, 2021

Dermatophytosis is superficial fungal infections caused by Dermatophytes, a group of fungi that are capable of invading the keratin of skin, hair and nails and this included Trichophyton, Microsporum and Epidermophyton. Objectives 1. To determine prevalence and to identify the etiological agent causing Dermatophytosis in tertiary care hospital. Material and Methods: This is an observational study conducted in the department of Microbiology. A total of 74 samples from patients clinically suspected to have Dermatophytosis were collected and transported to Microbiology laboratory. Direct examination for fungal element was done using 10% KOH for skin and hair, and 40% KOH for nail sample. Culture was done on Sabouraud's dextrose agar with gentamicin, cycloheximide and Dermatophyte Test medium. Result: Out of 74 clinically suspected cases, 42(56.75%) were culture positive and 44(59.45%) were KOH positive for fungal element. More number of cases were observed between age group of 31-40 yr. Tinea corporis was more common clinical presentation. Trichophyton mentagrophyte was the common isolate recovered. Conclusion: Dermatophytosis is a commonly seen fungal infection in developing countries like India. Diagnosis of these infections requires proper clinical examination and laboratory diagnostic aids. Early diagnosis and prevention of predisposing factors play a major role in control of dermatophyte infection.

Pattern of dermatophytes among skin, hair, and nail specimens in a tertiary care hospital of Lahore

Journal of Fatima Jinnah Medical University, 2022

Background: Dermatophytes are considered to be the most common cause fungal of infections globally. The geographical distribution of these fungi varies from region to region. The aim of this study was to isolate and determine the frequency and variety of various dermatophytes from clinically suspected cases of dermatophytoses. Patients and methods: This was a descriptive study carried out at the Department of Microbiology, Post graduate Medical Institute, Lahore over a period of nine months from July 2013 till March 2014. Nonprobability convenient sampling was used. One hundred clinically suspected cases of dermatophytosis were selected for this study. Specimen of skin, hair and nail were taken from patients and were evaluated by both microscopic examination and culture. Dermatophytes were identified based on the colony morphology as well as microscopic arrangement of macroconidia and microconidia. Data was collected and entered in Statistical Package for the Social Sciences (SPSS) version 20.0. Results: Out of a total of 100 patients, 48 were male and 52 were female. The majority of cases were from the age group of 31-40 (25%) followed by less than 10 years (18%). Out of hundred patients, 59 (59%) were positive on direct microscopy with KOH wet mount. Fungal culture was positive in 56 (56%) cases. Out of these 56 positive cultures, twenty-three were identified as dermatophyte species. Trichophyton rubrum was the commonest isolate. Other dermatophyte species isolated were Trichophyton mentagrophytes, Trichophyton verrocosum, Microsporum canis, Trichophyton tonsurans, and Microsporum audonii. Conclusion: Studying the pattern of dermatophyte species is necessary as it helps in the early diagnosis and treatment of dermatomycoses. This study identified Trichophyton rubrum as the commonest etiological agent of dermatophytoses.