Green Synthesis of Metallic Nanoparticles Using Leaf Extract of Calotropis Species and their Applications: A Review (original) (raw)
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Biosynthesis of Metallic Nanoparticles from Medicinal Plants: A Review
Journal of Nanoscience and Technology, 2019
Biosynthesis of nanoparticle from various medicinal plants has been effectively used in controlling the various diseases. Secondary metabolites which are derived from various plant parts such as leaves, stems, roots, shoots, flowers, barks and seeds through extraction used as reducing agents for bioreduction reaction. The secondary metabolites present in the plants such as terpenoids, flavones, ketones, aldehydes, alkaloids, tannins, phenolics and saponins used in the biological synthesis of nanoparticles which are a less toxic and non-hazardous method as compare to the other physical and chemical biosynthesis. Various metals such as cobalt, copper, silver, gold, palladium, platinum, zinc oxide and magnetite are used for nanoparticle synthesis. There are different techniques which are used to characterize nanoparticles such as UV-visible (vis) spectrophotometer, dynamic light scattering (DLS), scanning electron microscopy (SEM), transmission electron microscopy (TEM), energy-dispersive spectroscopy (EDS) and Fourier transform infrared spectrometer (FTIR). Plant derived nanoparticles shows various pharmacological applications such as anti-bactericidal activities, anti-fungicidal activities, antiplasmodial activity, anti-inflammatory action, anticancer studies, antiviral effects, antidiabetic and antioxidant activities.
The field of nanotechnology mainly encompasses with biology, physics, chemistry and material sciences and it develops novel therapeutic nanosized materials for biomedical and pharmaceutical applications. The biological syntheses of nanoparticles are being carried out by different macro-microscopic organisms such as plant, bacteria, fungi, seaweeds and microalgae. The biosynthesized nanomaterials have been effectively controlling the various endemic diseases with less adverse effect. Plant contains abundant natural compounds such as alkaloids, flavonoids, saponins, steroids, tannins and other nutritional compounds. These natural products are derived from various parts of plant such as leaves, stems, roots shoots, flowers, barks, and seeds. Recently, many studies have proved that the plant extracts act as a potential precursor for the synthesis of nanomaterial in non-hazardous ways. Since the plant extract contains various secondary metabolites, it acts as reducing and stabilizing agents for the bioreduction reaction to synthesized novel metallic nanoparticles.
Medicinal Plant Extract Mediated Green Synthesis of Metallic Nanoparticles: A Review
INTERNATIONAL JOURNAL OF PLANT AND ENVIRONMENT
The use of medicinal plant resources in the biosynthesis of metallic nanoparticles (MNPs) is remarkable in nanobiotechnology for its unique physicochemical and biological properties such as morphological diversity, large surface area by volume proportion, conductivity, stability, dispersity, and toxicity to microbes, or cancerous cells. Active phytochemicals or bioactive compounds in various medicinal plants such as flavonoids, phenolic acids, terpenoids, steroids, ascorbic acids etc. are capable of the bio-fabrication of various MNPs during the green synthesis. The biosynthesis method has a great potential to improve the manufacture of nanoparticles (NPs) without using any harmful and costly materials or chemicals that have been widely used in other traditional processes. The present review aims to describe the biosynthesis of metallic NPs using medicinal plant extract as a reducing and stabilizing agent. This review also focuses on the current state of various characterization tec...
Current developments in green synthesis of metallic nanoparticles using plant extracts: a review
Metal nanoparticles (MNPs) produced by green approaches have received global attention because of their physicochemical characteristics and their applications in the field of biotechnology. In recent years, the development of synthesizing NPs by plant extracts has become a major focus of researchers because of these NPs have low hazardous effect in the environment and low toxicity for the human body. Synthesized NPs from plants are not only more stable in terms of size and shape, also the yield of this method is higher than the other methods. Moreover, some of these MNPs have shown antimicrobial activity which is consistently confirmed in past few years. Plant extracts have been used as reducing agent and stabilizer of NPs in which we can reduce the toxicity in the environment as well as the human body only by not using chemical agents. Furthermore, the presence of some specific materials in plant extracts could be extremely helpful and effective for the human body; for instance, polyphenol, which may have antioxidant effects has the capability for capturing free radicals before they can react with other biomolecules and cause serious damages. In this article, we focused on of the most common plants which are regularly used to synthesize MNPs along with various methods for synthesizing MNPs from plant extracts.
Biosynthesis of Silver Nanoparticles Using Calotropis gigantean Leaf
2011
Various plant materials for the synthesis of nanoparticles is considered a green technology, In the present study reports the synthesis of Silver nanoparticles were synthesized from Calotropis gigantea leaf and the formation of silver nanoparticles was observed with different time intervals. The results recorded from UV-Vis spectrum, scanning electron microscope, X ray diffraction and Fourier transfer infra red spectra. Those are the supported the biosynthesis and characterization of silver nanoparticles.
Green Synthesis of Metallic Nanoparticles Using Plant Compounds and Their Applications
Emerging Research on Bioinspired Materials Engineering, 2000
The advancement in nanoparticulate system has a great impact in many scientific areas. Metallic nanoparticles (NPs) such as silver, gold and copper were found to exhibit antibacterial and other biological activities. The phytochemical constituents (Tannins, flavonoids, terpenoids, saponins and glycosides) present in the plant extracts were used for the green synthesis of NPs of desired size and morphology. Moreover, these active molecules act as reducing and capping agents for the synthe¬sis of NPs, which makes them suitable for biomedical applications. Apart from many approach on synthesis of nanoparticles, green synthesis method becomes more preferable because of its ecofriendly and nontoxic approach. This approach might pave the path for researchers across the globe to explore the potential of different herbs in the synthesis of NPs. This chapter will discuss the synthesis of various metal NPs using plants and their phytochemical constituent's involved during the synthesis. A section devoted to the different applications will be presented.
Biocatalysis and Agricultural Biotechnology, 2020
The cornerstone of nanoscience and nanotechnology are nanoparticles which have immense power and functional ability in diverse fields. Nanoparticles are synthesized by physical, chemical methos but limitations are due to its toxicity. We have discussed few green synthesis routes which are eco friendly and less toxic methods, including alage, microorganisms, plants etc.. Expoiting the potential of medicinal plants, is one of the green synthesis routes and is significant because the current therapeutic approaches have toxicity problems and microbial multidrug resistance issues. As the metal nanoparticles have received great attention across the globe, so in this study we have discussed and focused many different metallic nanoparticles obtained by green synthesis using medicinal plants. We have also discussed the types, size and medicinal properties like antibacterial, antifungal, anticancer, antiviral activities of nanoparticles. The biomolecules, secondary metabolites and coenzymes present in the plants help in easy reduction of metal ions to nanoparticles. Such nanoparticles are considered as potential antioxidants and promising candidates in cancer treatment. The simplified model summarises the green synthesis, its characterization using physicochemical means and their biomedical applications. Succinctly, we have discussed the recent advances in green synthesis of metallic nanoparticles, milestones, therapeutic applications and future perspectives of biosynthesized nanoparticles from some important medicinal plants.
Plants
The application of metallic nanoparticles (MNPs), especially that of silver, gold, cobalt, and zinc as antimicrobial, anticancer, drug delivery, contrast, and bioimaging agents has transformed the field of medicine. Their functions, which are attributed to their physicochemical properties, have gained prominence in various technological fields. Although MNPs can be produced via rigorous physical and chemical techniques, in recent years, a biological approach utilizing natural materials has been developed. With the increasing enthusiasm for safe and efficient nanomaterials, the biological method incorporating microorganisms and plants is preferred over physical and chemical methods of nanoparticle synthesis. Of these bio-entities, plants have received great attention owing to their capability to reduce and stabilize MNPs in a single one-pot protocol. South Africa is home to ~10% of the world’s plant species, making it a major contributor to the world’s ecological scenery. Despite the...
Materials
There have been some reports demonstrating the biogenic synthesis of silver nanoparticles (AgNPs) using Calotropis procera (CP) plant extract; however, detailed in-depth debriefing of the vital synthesis parameter for rapid, facile, efficacious synthesis at varied temperatures with effectual characterization of nanoparticles and biomimetic attribute is lacking. This study presents a comprehensive demarcation of the sustainable fabrication of biogenic C. procera flower extract capped and stabilized silver nanoparticles (CP-AgNPs) synthesis with thorough phytochemical characterization and potential biological application. The results revealed that the successful synthesis of CP-AgNPs was instantaneous with the maximum intensity of the plasmonic peak ~400 nm, while morphological results revealed the cubic shape of nanoparticles. CP-AgNPs were found to present stable, well-dispersed, uniform, high anionic zeta potential, and crystalline nanoparticles with a crystallite size of ~23.8 nm....
Plant extract as reducing agent in synthesis of metallic nanoparticles: A review
2014
The aim of this paper is to discuss on the roles of plant extract in the synthesis of metallic nanoparticles. Recently, green technology through biosynthesis method has drawn great attention compared to the physical and chemical method. Biosynthesis was found to be more energy efficient and able to eliminate the use of hazardous chemicals. The biosynthesis using plant extract has several advantages since the use of microorganism required stringent control on cell culture. Furthermore, the reaction rate is much faster as compared to that of the microorganism methods. The important compounds in the plant extract are hydroxyl and carbonyl groups which act as reducing agent as well as stabilizing agent. Several studies have been carried out to optimize the extraction of these compounds such as plant drying technique, extraction temperature and type of extraction's solvent. The common method used to quantify the concentration of reducing agents in the extract is through Folin-Ciocalteu method. Utilization of plant extract not only capable of producing well dispersed monometallic nanoparticles, but also bimetallic nanoparticles. Previous studies revealed that concentration of plant extract has significant effect on particle size and shape as well as particle distribution.