13-Tert-Butylergoline Derivatives (original) (raw)

Serotonergic ergoline derivatives

Maria Gioia Fornaretto

Bioorganic & Medicinal Chemistry Letters, 1998

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Synthesis and in vitro structure-activity relationship of 13-tert-butyl-ergoline derivatives as 5-HT1A receptor ligands

Sergio Mantegani

European journal of …, 1997

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D1 Agonist and/or D2 antagonist dopamine receptor properties of a series of ergoline derivatives: a structure–activity study

Maria Cervini, Mario Varasi, Emanuele Arlandini

European Journal of Medicinal Chemistry, 1999

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Resolved 6,7,8,9-tetrahydro-N,N-dimethyl-3H-benz[e]indol-8-amine: central dopamine and serotonin receptor stimulating properties

Kjell Svensson

Journal of Medicinal Chemistry, 1989

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SAR-studies on the importance of aromatic ring topologies in search for selective 5-HT7 receptor ligands among phenylpiperazine hydantoin derivatives

Monika Kubacka

European Journal of Medicinal Chemistry, 2014

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INFLUENCE OF ARYLPIPERAZINES AROMATIC STRUCTURE OVER DIFFERENTIAL AFFINITY FOR 5-HT 1A AND 5-HT 2A RECEPTORS

Irene Rebelo

Electronic Journal of Biomedicine

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Azaindole derivatives with high affinity for the dopamine D4 receptor: Synthesis, ligand binding studies and comparison of molecular electrostatic potential maps

Harald Hübner

Bioorganic & Medicinal Chemistry Letters, 1999

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N(1)-substituted ergolines and tryptamines show species differences for the agonist-labeled 5-HT2 receptor

James Audia

European Journal of Pharmacology, 1993

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A Rationale for the Activity Profile of Arylpiperazinylthioalkyls As 5-HT1A-Serotonin and [Alpha] 1-Adrenergic Receptor Ligands

kirti sarbhai

European journal of medicinal chemistry, 2010

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Dopamine/serotonin receptor ligands. Part 17: A cross-target SAR approach: Affinities of azecine-styled ligands for 5-HT2A versus D1 and D2 receptors

Christoph Enzensperger

Bioorganic & Medicinal Chemistry Letters, 2008

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Synthesis of 2-(5-Bromo-2,3-dimethoxyphenyl)-5-(aminomethyl)-1 H-pyrrole analogues and their binding affinities for dopamine D 2, D 3, and D 4 receptors

Yunsheng Huang

Bioorganic & Medicinal Chemistry, 2003

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Ergoline Derivatives as a Probe for Featuring the 5-HT 1A Receptor Pharmacophore

Alessandro Dolmella

Journal of Molecular Modeling, 1995

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A New Class of Arylpiperazine Derivatives: the Library Synthesis on SynPhase Lanterns and Biological Evaluation on Serotonin 5-HT 1A and 5-HT 2A Receptors

Maciej Pawłowski

Journal of Combinatorial Chemistry, 2004

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Structure–Activity Relationships of Receptor Binding of 1,4-Dihydropyridine Derivatives

Rahime Şimşek

Biological & Pharmaceutical Bulletin, 2008

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Novel Potent and Selective Central 5-HT 3 Receptor Ligands Provided with Different Intrinsic Efficacy. 2. Molecular Basis of the Intrinsic Efficacy of Arylpiperazine Derivatives at the Central 5-HT 3 Receptors

Maurizio Anzini

Journal of Medicinal Chemistry, 1999

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Functionally Selective Dopamine D 2 /D 3 Receptor Agonists Comprising an Enyne Moiety

Peter Gmeiner

Journal of Medicinal Chemistry, 2013

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Synthesis and receptor affinities of some conformationally restricted analogues of the dopamine D1 selective ligand (5R)-8-chloro-2,3,4,5-tetrahydro-3-methyl-5-phenyl- 1H-3-benzazepin-7-ol

R. Chipkin, Donald Hou

Journal of medicinal chemistry, 1989

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Influence of N-1 substituent properties on binding affinities of arylpiperazines to the binding site of 5HT1A receptor

Goran Roglic

Journal of The Serbian Chemical Society, 2006

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Design, synthesis and binding properties of novel and selective 5-HT3 and 5-HT4 receptor ligands

Maria Modica

European Journal of Medicinal Chemistry, 2000

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Structure-5-HT Receptor Affinity Relationship in a New Group of 7-Arylpiperazynylalkyl and 7-Tetrahydroisoquinolinylalkyl Derivatives of 8-Amino-1,3-dimethyl-1 H -purine-2,6(3 H ,7 H )-dione

Małgorzata Zygmunt, Paweł Żmudzki

Archiv der Pharmazie, 2015

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Synthesis and structure-affinity relationships of novel N-(1-ethyl-4-methylhexahydro-1,4-diazepin-6-yl)pyridine-3-carboxamides with potent serotonin 5-HT3 and dopamine D2 receptor antagonistic activity

Martha Ramirez

2003

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Structure–Activity Relationship and Evaluation of Phenethylamine and Tryptamine Derivatives for Affinity towards 5-Hydroxytryptamine Type 2A Receptor

SHUJIE WANG

Biomolecules & Therapeutics

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Dopamine receptor agonists: 3-allyl-6-chloro-2,3,4,5-tetrahydro-1-(4-hydroxyphenyl)-1H-3-benzazepine-7,8-diol and a series of related 3-benzazepines

Robert Demarinis

Journal of Medicinal Chemistry, 1986

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Synthesis, Biological Evaluation, and Docking Studies of Tetrahydrofuran- Cyclopentanone- and Cyclopentanol-Based Ligands Acting at Adrenergic α 1 - and Serotonine 5-HT 1A Receptors

Silvia Franchini

Journal of Medicinal Chemistry, 2012

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Introduction of a methyl group in α- or β-position of 1-heteroarylethyl-4-phenyl-piperazines affects their dopaminergic/serotonergic properties

Vukic Soskic

Archiv der Pharmazie, 2001

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Design and Synthesis of Bitopic 2Phenylcyclopropylmethylamine (PCPMA) Derivatives as Selective Dopamine D3 Receptor Ligands

Qingtong Zhou

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Synthesis of novel lactam derivatives and their evaluation as ligands for the dopamine receptors, leading to a D 4-selective ligand

Ashraf Abadi

Bioorganic & Medicinal Chemistry, 2007

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(.+-.)-3-Allyl-6-bromo-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine, a new high affinity D1 dopamine receptor ligand: synthesis and structure-activity relationship

John Neumeyer

Journal of Medicinal Chemistry, 1991

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