Spectrum of neoplastic sino-nasal lesions at tertiary care centre (original) (raw)
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Clinicopathological study of non-neoplastic and neoplastic sinonasal lesions
IP Innovative Publication Pvt. Ltd, 2017
In this retrospective study, comprising of 88 cases, various sinonasal lesion both common and rare are studied. All lesions were described, diagnosed histopathologically and classified as per WHO classification. The sample consist of patient in the age group 10 years to 70 years. The study also compares sex differences, symptomatology and the relative incidence of various lesions. The commonest site was nasal cavity, followed by paranasal sinuses. They occur commonly in second and third decade with predominance in males. Out of 88 sinonasal lesion, 73 were non-neoplastic, 10 were benign and 5 were malignant. Amongst non-neoplastic lesion Inflammatory polyp was most common and Inverted papilloma was most common amongst benign lesion. Amongst the malignant lesion commonest lesion was sqaumous cell carcinoma. Sinonasal lesion have wide range of possibilities, so high degree of suspicion with early histopathological examination to exclude or confirm malignancy is essential.
Histopathological Analysis of Sinonasal and Nasopharyngeal Lesions- A Retrospective Study
NATIONAL JOURNAL OF LABORATORY MEDICINE
Introduction: Sinonasal and nasopharyngeal lesions is a common problem in the present environment with diagnostic and therapeutic dilemma. Majority of the lesions present clinically as polypoid masses. Histopathological examination of these lesions is essential for the definitive diagnosis because management and prognosis vary among different lesions. Aim: To determine the incidence of various nasal lesions reported in a rural tertiary care hospital, and to compare these lesions in relation to demographic data of the patients. Materials and Methods: This retrospective study was conducted on the specimens received at histopathology section from the ENT department of a tertiary care hospital from April 2018 to November 2021. The specimens were fixed in 10% formalin, processed and then stained with haematoxylin and eosin. Required data were obtained from the histopathology records. Results: The present study was conducted on a total of 100 cases. Amongst these, 61 were males and 39 wer...
2017
Background: The nasal cavity and paranasal sinuses are collectively referred to as the sinonasal tract, which is anatomically and embryologically distinct from the nasopharynx. Aim and objectives: To understand the variable clinical presentations of three unusual cases in the sinonasal tract, to study the histomorphology and analyze the pitfalls in their diagnosis, to study the differential diagnosis and review the literature. Materials and methods: Unusual presentations of three cases were encountered during the period from October 2016 to July 2017 in the Department of Pathology, Government ENT Hospital, Hyderabad. Excised specimens of all the three cases were received and subjected to routine processing, cutting, staining and histopathological features were analyzed. Special histochemical and immunohistochemical stains were done for confirmation of final diagnosis. Results: Case 1 was Rosai Dorfman Disease, Case 2 was Botryoid Embryonal Rhabdomyosarcoma and Case 3 was Invasive As...
Histopathological Patterns of Sinonasal Masses: A Hospital-Based Study
Journal of Evolution of Medical and Dental Sciences, 2016
BACKGROUND Sinonasal masses are one of the commonest cause of nasal obstruction with or without nasal discharge. Sinonasal masses may show diverse histopathological patterns. The sinonasal masses may be non-neoplastic lesions like nasal polyps either inflammatory or allergic type, traumatic lesions, granulomatous lesions or neoplastic lesions. Neoplasms of sinonasal masses form a wide spectrum like angiofibroma, capillary haemangioma at one end while squamous cell carcinoma at the other end of the spectrum. Benign neoplastic lesions arising from nasal cavities, paranasal sinuses and nasopharynx may threaten the patients because of their high recurrence rate and propensity for malignant potential. Any masses, which are seen in the area of nasal cavities and paranasal sinuses are termed as "sinonasal masses." Histopathological examination is the only means of determining the nature and patterns of these sinonasal masses, i.e. non-neoplastic versus neoplastic. AIMS AND OBJECTIVES A hospital-based study to determine the histopathological patterns of sinonasal masses. MATERIALS AND METHODS The present study was based on histopathological analysis of 120 specimens of sinonasal masses presented at Pathology
2016
Background: The nasal cavity and paranasal sinuses are collectively referred to as the sinonasal tract, which is anatomically and embryologically distinct from the nasopharynx. Aim and objectives: To understand the variable clinical presentations of three unusual cases in the sinonasal tract, to study the histomorphology and analyze the pitfalls in their diagnosis, to study the differential diagnosis and review the literature. Materials and methods: Unusual presentations of three cases were encountered during the period from October 2016 to July 2017 in the Department of Pathology, Government ENT Hospital, Hyderabad. Excised specimens of all the three cases were received and subjected to routine processing, cutting, staining and histopathological features were analyzed. Special histochemical and immunohistochemical stains were done for confirmation of final diagnosis. Results: Case 1 was Rosai Dorfman Disease, Case 2 was Botryoid Embryonal Rhabdomyosarcoma and Case 3 was Invasive Aspergillosis. Conclusion: Rosai Dorfman Disease has to be differentiated from lymphoproliferative and other histiocytic disorders while the benign inflammatory pattern of Botryoid Embryonal Rhabdomyosarcoma is invariably mistaken for an inflammatory process. Aspergillosis mimics as a neoplastic lesion, by its expansile invasive nature. Thus an inflammatory lesion may be mistaken for neoplastic growth and vice versa which can lead to erroneous diagnosis, improper therapy and poor outcome.
2016
Introduction: Neoplasms of the sinuses and nasal cavity account for 0.2–0.8 % of all carcinomas. The present study was carried out to find out correlation of clinical, radiological and histopathological diagnosis of sinonasal masses. Material and Methods: The present study was carried out on 60 patients of any age and sex randomly selected who presented with sinonasal masses in the department of Otorhinolaryngology and Pathology in Guru Gobind Singh Medical College and Hospital, Faridkot. These cases were subjected to routine hematological and biochemical evaluation, nasal endoscopy, xray paranasal sinuses/ CT scan and biopsy. Tissues were routinely processed for histopathological sections of 5 micron thickness and were stained by hematoxylin and eosin stain. Special staining by reticulin, von gieson, PAS and masson’strichrome were undertaken whenever applicable. The data so obtained was compiled, analyzed and valid conclusion drawn. Results: In present study, histopathology showed ...
The Utility of Clinicopathological Correlation of Sinonasal Masses in a Tertiary Hospital
Journal of Evolution of Medical and Dental Sciences
BACKGROUND Sinonasal masses are commonly seen lesions in ENT practice with multiple aetiological factors. We wanted to study the clinico-pathological features of nasal mass specimens in a tertiary hospital and evaluate the utility of routine histopathological examination of the surgically removed nasal tissue specimens. METHODS All the histologically examined specimens of patients clinically presenting with nasal or sinonasal lesions over a period of one year were retrospectively studied and analyzed. RESULTS Out of total 36 patients with masses, 21 were males (58.3 %) and 15 (41.7 %) were females. The age ranged from 10 to 75 years with a mean age of 31.4 years and maximum patients were in the third decade (37.5 %). The most common presenting clinical symptom was nasal obstruction that was seen in 33 patients (91.6 %). Computed tomography (CT) scan was done in 94.5 % of cases prior to the surgical intervention. One fifth of the sinonasal lesions were neoplastic as per histopatholog...
CLINIC-PATHOLOGICAL PROFILE OF SINONASAL MASSES
A wide majority of lesions in the nose and the paranasal sinuses present as polypoidal mass in the nasal cavity. The Inflammatory conditions, infections, chronic rhino sinusitis, benign lesions and even malignancies can also present as nasal polyps. Early stage of malignancies in the nose is often misdiagnosed inadvertently. This is because malignancies too present as mass in the nose that mimics benign lesions and often associated with chronic rhino sinusitis. The present study was undertaken to know the clinic-pathological profile of sinonasal masses. The study group included 102 patients with nasal polypoidal masses, all patients were subjected to detailed history and clinical examination. All necessary investigations were done at greater accuracy. The final diagnosis was made after the histopathological examination of the excised masses. Depending on the final diagnosis, all masses were divided into non-neoplastic and neoplastic groups. Total 102 patients who presented with nasal polypoidal masses, of which 89 turned out to be non-neoplastic lesions and 13 were neoplastic, study showed that non-neoplastic lesions are very more common than neoplastic lesions. The Male patients were more prone to the formation of lesions when compared with non-neoplastic lesions. The nasal polyps were formed eighty-one percent. The study can found that, there is a high chance of discrepancy between the clinical and histopathological diagnosis.
Different Faces of Sinonasal Mass Lesions
Bengal Journal of Otolaryngology and Head Neck Surgery
Introduction Mass in the nasal cavity presents with a wide range of symptoms, when a presumptive diagnosis is often made with the help of imaging and endoscopy. This study focussed on correlating clinical diagnosis with the histopathological diagnosis so that appropriate treatment can be offered to improve the quality of life of the patient. Materials and Methods The study included 120 cases who presented with symptoms and signs of mass in the nasal cavity, undergoing surgery or diagnostic biopsy. They were evaluated with a detailed history and clinical examination, diagnostic nasal endoscopy, and relevant radiological investigations. Histopathological examination of the biopsy of the excised specimen was performed by Haematoxylin and Eosin stain. Special stains and Immunohistochemistry (IHC) were performed whenever indicated. The clinical diagnosis was correlated with histopathological diagnosis. Results Nasal obstruction was the most frequent symptom followed by nasal discharge. N...