Clinico-mycological study of dermatophytosis in a tertiary-care hospital in Ghaziabad (original) (raw)
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Clinico-Mycological Study of Dermatophytic Infections in a Tertiary Care Hospital of South Delhi
Journal of Evidence Based Medicine and Healthcare, 2020
BACKGROUND Dermatophytosis is a superficial fungal infection commonly referred to as ringworm or tinea. It remains a public health problem, which is prevalent in all age groups and both the sexes. The prevalence and mycological profile of dermatophytosis varies across populations and also keeps changing from time to time in a particular population. This study was conducted to study the clinicomycological profile of dermatophytic infection in our population. METHODS 117 patients over a period of one year were enrolled for the study. All patients were thoroughly examined, and clinical details were noted. The sample obtained by skin / nail / hair scrapings was divided into two parts: one for KOH mount and another for fungal culture. Following direct microscopic examination with KOH, the scrapings (skin, hair and nail) were inoculated into slopes of duplicate sets of tubes containing Sabouraud's dextrose agar and dermatophyte test medium. The isolates were identified by studying the culture characteristics, pigment production, and microscopic examination of the lactophenol cotton blue mounts and slide culture. RESULTS Males were found to be more commonly infected (M : F = 2.4 : 1). The most common age group affected was 16-30 years (49 patients, 41.8 %) followed by 31-45 years age group (35 patients, 29.9 %). Tinea corporis was the most common clinical presentation (54, 46.1 %) followed by tinea manuum (21, 17.9 %), tinea cruris (13, 11.1 %), tinea unguium (13, 11.1 %), tinea faciei (6, 5.1 %), tinea pedis (5, 4.2 %) and mixed (5, 4.2 %). In 52 (44.4 %) patients, KOH positivity was seen while 48 (41 %) patients showed culture positivity. The most common dermatophytes isolated were T. mentagrophytes (25, 59.5 %) followed by T. rubrum (10, 23.8 %), T. tonsurans (6, 14.2 %) and Epidermophyton floccosum (1, 2.3 %). CONCLUSIONS T. mentagrophytes is the most common organism causing dermatophytosis in our population. An epidemiological shift of type of fungus seems to have occurred when compared to previous study in which T. rubrum was the most common organism isolated. Also, most common clinical pattern observed was tinea corporis followed up by tinea manuum which is different from the previously observed pattern. The present study demonstrated the clinico-mycological pattern in our population which can be utilized in framing policies and treatment guidelines.
“Clinicomycological Study of Dermatophytosis At Tertiary Care Hospital In Bhavnagar, Gujarat”
Dermatophytes are the Infection of the skin, hair or nails caused by a group of keratinophilic fungi, called dermatophytes, also known as Tinea or ring worm.The study aimed to find Clinico-Mycological correlation of dermatophytosis and to find out various species of dermatophytes prevalent in & around Bhavnagar city. Materials and Methods: Skin, hair and nail samples from 600 clinically suspected cases of dermatophytosis were screened by direct microscopic examination using 10% potassium hydroxide (KOH) mount and inoculated for culture in Sabouraud dextrose agar (SDA) and dermatophyte test medium (DTM).
Clinicomycological profile of dermatophytosis in a tertiary care teaching hospital, Vadodara
Indian Journal of Microbiology Research, 2023
Background: Dermatophytosis is the most common type of cutaneous fungal infection seen in man infecting the superficial keratinized layer of the skin, hair and nails. The aim of the study is to isolate and identify the dermatophytes from clinically suspected cases of dermatophytosis, to determine the frequency of occurrence of various species of dermatophytes, to know the prevalence of age and sex of dermatophytosis in the locality. Materials and Methods: The present study was carried out in the Department of Microbiology, Medical College and SSG Hospital, Vadodara. A total of 150 clinically diagnosed cases of dermatophytosis were taken for this study. Skin, hair and nail samples were aseptically collected and were subjected to KOH mount examination and culture. Differentiation of the dermatophyte species was performed based on the macroscopic and microscopic examination of culture and physiological test including urease test. Results: Tinea corporis (41.3%) was the commonest clinical type with a male to female ratio of 1.05:1. Out of these samples, dermatophytes were isolated in 108 cases with the overall isolation rate of 72%. Seven species of dermatophytes were isolated. T.mentagrophytes 53 (49.1%) was the commonest species followed by T.rubrum 22(20.4%). Conclusion: Identifying dermatophyte species and knowledge of their host preference and ecology play an important role in treating the patient. Correct and efficient laboratory methods for diagnosis of dermatophytosis is the need of the hour to provide correct and timely treatment and prevent the further spread and chronicity of the disease. Keywords: Dermatophytes, Tinea corporis, Trichophyton mentagrophytes
Clinico-mycological study of dermatophytosis in a tertiary care centre in North Eastern India
2020
Background: The dermatophytosis constitutes a group of superficial fungal infections of keratinized tissues, namely, the epidermis, hair, and nails. The present study was undertaken to find out the clinical profile of dermatophytosis and to identify the causative fungal species in the various clinical presentations. Materials & Methods: This was a hospital‐based observational study. One hundred clinically suspected patients attending OPD of M. G. M. Medical College and Lion Seva Kendra Hospital were included in the study. History was taken, general physical and cutaneous examination was done and details of skin lesions noted. Direct microscopy in 10% KOH (40% KOH for nail) and fungal culture on SDA with 0.05% chloramphenicol and 0.5% cycloheximide was done in every case. Chi‐square test and contingency coefficient test were used as significant tests for analysis. Results: In the present study, tinea accounted for 22.68 % of the total Dermatology OPD cases of which male constituted 5...
Epidemiological Study Of Dermatophytosis In Okara, Pakistan
2016
A clinical study was carried out among patients with tinea infections in Okara during the year 2013-2014 with respect to age, gender and clinical presentation of the infection. A total number of 150 samples were collected from tinea infected patients out of which only 120 were found positive for Trichophyton spp and Microsporum spp and no Epidermophyton was observed. Among positive cases Trichophyton spp was most dominant (68.3%) followed by Microsporum spp. (38%). The most effected age group was 0-10 years (40.8%). Male patients were infected more as compared to females and male to female ratio among positive cases was observed as 17:13. Rural community was observed to be most affected by the dermatophyte fungus. This study manifests the importance of correct mycological diagnosis for effective disease management.
Clinical patterns and etiology of dermatophytosis in 200 cases in Babol, North of Iran
Caspian Journal of Internal Medicine, 2010
Background: Dermatophytosis is a very common fungal infection of skin, hair and nail caused by dermatophytes. The purpose of this study was to evaluate the clinical patterns and etiology of dermatophytosis in Babol, Northern Iran. Methods: From September 2003 to December 2005, 200 patients with dermatophytosis who were admitted in the dermatology clinic of Babol Medical University were studied. The diagnosis of the fungal infection was performed in both, direct smear and culture. Results: All patients were positive with direct smear and culture. The frequency of the disease was equal between the male (52%, female (48%)). Tinea cruris (24.5%), tinea pedis (20%), tinea corporis (17%), tinea ungium (15.5%), were the most common dermatophytosis. Trichophyton mentagrophyte was the most prevalent species followed by Epidermophyton floccosum. Conclusion: The results show that tinea cruris and tinea pedis were the most common dermatophytosis in our region. Trichophyton mentagrophyte and Epidermophyton floccosum were the most etiologic agents.
Microbiology Research Journal International, 2019
Dermatophytosis or tinea is a type of cutaneous infection caused by keratinophilic fungi, infecting the skin, nails and hair. A correct diagnosis is important for epidemiological purposes and initiating appropriate treatment. An increase in the prevalence of fungal infection worldwide is due to abuse of antibiotics, immunosuppressive treatments and numerous medical conditions. Aim: To isolate, identify, and examine the in-vitro antifungal susceptibility of dermatophytes in clinically suspected cases of tinea infections. Methodology: After taking informed consent, we took 65 patients suspected of tinea infection and obtained samples from skin, hair and nail, under aseptic precautions, at Department of Microbiology, University of Health Sciences (UHS), Lahore, Pakistan. The identification of dermatophytes was performed using potassium hydroxide (KOH) mounts and culture on Sabouraud Dextrose Agar (SDA) and Dermatophyte Test Medium (DTM). The cultures were incubated at 30ºC for up to 4 ...
A preliminary clinico-mycological study of dermatophytes infection
International Journal of Research in Medical Sciences
Background: Superficial fungal infections are the most common skin diseases, affecting millions of people throughout the world. Aim of the study was carried out to find, the effect of seasonal variation and socio-economic status on the prevalence of dermatophytes.Methods: A total of fifty clinically suspected cases of dermatophytosis were subjected to mycological studies.Results: Out of which 32 (64%) were culture positive Tinea corporis was the most common clinical type followed by Tinea cruris. Tricophoton rubrum 17/32 (53.12%) was the most common isolate followed by T. mentagrophytes 9/32(28.12%), T. tonsurans 3/32(9.37%), T. verrrucosum 2/32(6.25%) and T. schoenleinii 1/32(3.12%). Most of the patients belonged to the middle socio-economic group (28/50) followed by lower socio-economic group (19/50) maximum cases of dermatophytosis were reported from June to August revealing the fact that hot and humid weather during the monsoons has a great impact on the occurrence of dermatophy...
A clinicomycological study of dermatophytic infection in a tertiary care hospital
IP Innovative Publication Pvt. Ltd., 2018
Introduction: Dermatophytosis is a mycotic infection of the hair, skin or nails. Although dermatophytic infection doesn’t cause mortality, it can lead to morbidity and result in a major public health issue usually in tropical countries like India, because of the supporting climatic conditions like high temperature and air moisture. The present study was undertaken to know the clinical status of dermatophytic infection and to isolate and identify the species commonly seen in our area. Materials and Methods: A total of 166 clinically suspected cases of dermatophytosis sent for department of Microbiology were studied over a period of one year. KOH for microscopy and culture on Sabouraud's dextrose agar slopes was done. Species identification was done by studying growth morphology, slide culture and biochemical tests like urease test. Results: Among 166 patients, the dermatophytosis was more common among the age group of 21-30 years. Males (55.5%) were more affected than females (44.5%). The most common clinical type was tinea corporis (36.2%) followed by tinea incognito (10.3%). Out of 166 patients, 125 cases (75.3%) were positive for fungi by KOH and 118 cases (71.1%) showed growth in culture. Trichophyton spp are predominantly isolated (88%). Conclusion: The prevalence of dermatophytosis usually differ with respect to various geographical locations. India due to high humidity and temperature acts as a rich ground for the heavy growth of dermatophytes. Idea regarding the fungal infections prevalent in the particular region is important to know the burden of infection and its course of infection. This helps to plan for the proper infrastructure required for various epidemiological and laboratory studies, and further to evaluate interventions required for treatment. Keywords: Dermatophytosis, Trichophyton, Tinea.