Prevalence of Ulcerative Colitis in Patients Who Underwent Colonoscopy in Benha University Hospitals (original) (raw)
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Afro-Egyptian Journal of Infectious and Endemic Diseases, 2018
Background and study aim: Colonoscopy is recommended by many international gastroenterology and cancer societies as the initial diagnostic modality for colorectal cancer. It is considered the most accurate diagnostic tool in inflammatory bowel disease. These are two identified subtypes of the disease, ulcerative colitis (UC) and Crohn's disease. The previous studies on Egyptian patients said that the incidence of IBD increased significantly in the past ten years. The aim of this study was to calculate the prevalence of IBD among patients referred to endoscopy units to perform colonoscopy and define the most common presenting symptoms of IBD. We also wanted to shed light on the most common presenting complaints that lead to referral to colonoscopy and the common colonic lesions that were diagnosed by colonoscopy.r Patients and Methods: Cross sectional study involved 250 patients who underwent colonoscopy in the period from November 2014 to November 2015, the presenting complaint was recorded as well as the results of colonoscopy. Results: Bleeding per rectum was the commonest indication for colonoscopy (46%) followed by chronic abdominal pain (20%), then chronic diarrhea (17%). The commonest pathological conditions were internal hemorrhoids in 27.6% followed by nonspecific colitis in 20.4%, ulcerative colitis in 10.4%, carcinoma in 10.4%, Crohn's in 0.8% then polyps in 0.4%. UC/CD ratio was 13:1. Conclusion: In a group of Egyptian patients undergoing colonoscopy the most frequent diagnosis were internal piles, non-specific colitis followed by inflammatory bowel disease with a prevalence of 11.2% and predominance of UC over CD.
International Journal of Research in Medical Sciences, 2014
Ulcerative colitis is a recurrent chronic inflammatory disease of the intestines with unknown etiology and is associated with Crohn's disease which is categorized in IBD class. This disease is caused by abnormal local immune system response to intestinal flora or may be to some self-antigens in genetically susceptible individuals. Ulcerative colitis is a non-granulomatous disease limited to the colon and with exception in severe cases is limited to the mucosa and submucosa. 1 It is estimated that the number of people with this disease in Iran is near to 10000 people. The incidence of the disease has increased in recent decades. The incidence of Crohn's disease and ulcerative colitis in different geographic regions vary from 0.1 to 11 and 0.5 to 24.5 per 1000 person, respectively. 2 The disease is more common in whites in the United States and there was no sexual preference. The incidence of Colitis in North America is 10-12 per 100000 people, with a peak age incidence of 15-25 years old. 3 The incidence of ulcerative colitis is one in a thousand. The overall shape of the data distribution of ulcerative colitis is as a bi-wavelike in which a second peak occurs in the sixth decade of human life and affects women more than men. Geographical distribution of colitis and colonic diseases in the world is the same with high incidence in United States, Canada, United Kingdom and Scandinavia. High incidence has been seen in northern Europe and America than in southern. 4 The most incidence rate of inflammatory bowel disease is ABSTRACT Background: Ulcerative colitis is one of the inflammatory bowel diseases with unknown etiology. Genetic and environmental factors are thought to be effective in this disease. The aim of this study is to assessment of demographic features and clinical symptoms of ulcerative colitis patients refereed to Emam hospital in Ardabil city. Methods: In this retrospective cross-sectional study, 80 cases of ulcerative colitis referred to Emam hospital in Ardabil city were evaluated during 2004-2011. The diagnosis was confirmed based on clinical features, colonoscopy, and pathology and resulting of other causes. Data were collected through direct interview and analyzed by statistical method in SPSS software. Results: Mean age of patients was 36.4 (SD=18.4). Duration of symptoms onset until diagnosis was 8 months. Male to female ratio was 0.8/1. 38(47.5%) of patients were male and 42 (52.5%) were female. 3 (3.75%) of patients have history of positive UC and 4 (5%) history of appendectomy. According to colonoscopy finding, 1 (1.25%) have rectum involvement, 27 (33.75%) recto sigmoid, 23 (28.75%) left side colon and 4 (5%) have pan colitis. Conclusion: Results showed that in compare with other places, clinical signs of ulcerative colitis in Ardabil province are different and so doing other d epidemiologic studies based on population to determine incidence and prevalence ulcerative colitis in Ardabil province is necessary.
Assessment of Severity of Ulcerative Colitis on First Colonoscopic Examination
PAFMJ
Objective: To assess the severity of ulcerative colitis on first colonoscopic examination. Study Design: Prospective cross-sectional (correlational) study design. Place and Duration of Study: Study was conducted in Gastroenterology Outpatient Department of Pak Emirates Military Hospital, Rawalpindi, from Nov 2017 to Oct 2018. Methodology: An aggregate of 200 patients within the age range of 12-70 years, were included in the studythrough non-probability consecutive sampling. The data was collected by the self-administered questionnaireincluding age, gender, stool frequency, P/R bleed, systemic features of ulcerative colitis & colonoscopic findings.Effectiveness of the procedures was noted on a pre-designed performa and the endoscopic assessment was based upon mayo score severity of colitis graded from Normal (0) to Severe (3). Data was analyzed by using SPSS-19. Results: The mean age of the participants was reported 38 ± 2.1 years. Out of 200 participants 104 (52%) weremale, diarrhea...
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy, 2016
Background: The prevalence ulcerative colitis (UC) in RSCM Jakarta in 1991-1995 is 2.5%. The disease affects men and women at similar rates or slightly more common in women than in men. Age of onset follows a bimodal pattern, with a peak at 15-25 years and a smaller one at 55-65 years, although the disease can occur in people of any age. The precise etiology of UC is not well understood. UC is precipitated by a complex in Dr. Saiful Anwar General Hospital Malang. Method: This is a retrospective survey analysis from medical record which was taken from 2170 patients who underwent colonoscopy in Dr. Saiful Anwar General Hospital Malang from January 2010 to December 2014. Demographic setting (sex, age), clinical features, lifestyle, diagnosis based on colonoscopy were analyzed as the variables. Results: Total patients with UC was 176 patients. The prevalence of UC during 2010-2014 was 8.2% at Dr. Saiful Anwar General Hospital. There was a similar prevalence of sex between male and female patients, in which 95 (53.4%) were male and 81 (46.6%) were female. The average age of patients with UC was 41,6 years. Most patients were presented with abdominal pain (32.90%) and weight loss (42.1%). The diagnosis based on colonoscopy were pancolitis (36%), proctosigmoiditis/proctitis (31.81%), and left-sided colitis (21.9%). The risk Majority of ulcerative colitis study samples were non-smoker (75%), not consuming herbal treatment/NSAID diet and UC (r =-0.106, p = 0.000). Conclusion: average age was 41.6 years. Patients presented with various clinical symptoms, most are abdominal pain and
TAJ: Journal of Teachers Association
Ulcerative colitis is an idiopathic inflammatory bowel disease characterized by continuous mucosal inflammation that starts in the rectum and extends proximally. Ulcerative colitis is considered frequent in majority of European and North American population and exceptional in most of the developing Asian countries. The present study was designed to estimate the disease severity and colonic involvement of ulcerative colitis in a tertiary care hospital of Rajshahi Medical College. The study population includes of 60 ulcerative colitis patients. Patients were categorized on the basis of disease severity ; moderate : 34, and severe: 26 and involvement of colon: 28 (46.40%) pancolitis, 20 (33.96%) left sided colitis and had 12 (19.61%) proctosigmoiditis.
Ulcerative Colitis: Experience at a Tertiary Care Center
Rawal Medical Journal, 2005
Objective: Ulcerative colitis has a worldwide distribution but its prevalence and clinical patterns in Pakistan are not known. This study was performed to ascertain the clinical patterns of ulcerative colitis in patients referred to a tertiary care center. Methods: All patients presenting with diarrhea, blood in stools and biopsy proven for ulcerative colitis were prospectively followed for clinical features, laboratory findings, endoscopic features and treatment response over the study period. Results: A total of 85 patients were seen and followed for up to 8 years. All had diarrhea with blood in stools. All had numerous white blood cells in stool. Erythrocyte sedimentation rate was elevated in 94 % of patients. More than half had mild disease and distal colitis. All patients responded well to standard treatment with anti-inflammatory drugs. 2 Conclusion: Most patients of ulcerative colitis were mild in severity and had distal involvement. Clinical features in this cohort were similar to patients in most other parts of world. All responded to standard treatment.
The Sigmoidoscopic extent of ulcerative colitis and associated factors in Pakistani population
2021
In this retrospective cohort study, patients who underwent sigmoidoscopy from July 2013 to July 2020 at Liver Clinic, Jail Road, Lahore, were categorized into two cohorts: who had ulcerative colitis confirmed on histology and who had no ulcerative colitis. Extent and severity of the disease as well as coexisting pathologies were also noted. SPSS version 25 was used. Independent sample T-test was applied to compare quantitative variables like age and weight, and chi-square test to compare qualitative variables with two cohorts. The p-value less than 0.05 was opted as significant. Odd ratio with 95% confidence interval (CI) were also computed for each association. Results: About 11.55% patients (165 out of 1428) had ulcerative colitis, whose mean age and mean weight were 38.27 ± 14.15 years and 74.08 ± 13.20 Kg respectively. Among ulcerative colitis patients, 18.2% had proctitis, 22.4% had proctosigmoiditis, 27.7% had left-sided colitis, and 31.5% had extensive colitis. May endoscopic severity score was found 0,1,2, and 3 in 12.1%, 23.6%, 31.5%, and 32.7% patients respectively. Ulcerative colitis cohort had significant association with younger age (p<0.01), female gender (p<0.01), non or former smoking (p=0.02) and presentation with bloody diarrhea (p<0.01), and no association with body weight (p=0.311), presence of diabetes mellitus (p=0.311) and family history of IBD (P=0.368). Conclusion: Endoscopic extent and severity of ulcerative colitis is high in our studied population. Ulcerative colitis is more prevalent in younger age and female gender patients who presented with bloody diarrhea, while the presence of active smoking has negative association with finding the ulcerative colitis. However, presence of family history of IBD, diabetes mellitus and body weight of the patient has no statistical correlation with finding ulcerative colitis during sigmoidoscopic examination in our patients.
Revision of the demographic and clinical data of patients with ulcerative colitis in Turkey
Medicinski glasnik : official publication of the Medical Association of Zenica-Doboj Canton, Bosnia and Herzegovina, 2017
Aim To evaluate the demographic and clinical data of fifty two patients with the diagnosis of ulcerative colitis. Methods A total of 52 patients diagnosed with ulcerative colitis by clinical, endoscopical and histopathological evaluations were included the study. Demographic data, colon involvement site of the disease and disease severity were examined from the patients' records. The patients were divided into groups according to the Baron grading system. Results Distribution of patients according to the colon involvement site was: 10 (9.2%) rectal, 16 (30.8%) rectosigmoid, 13 (25%) left sided, 10 (19.2%) extensive colitis and 3 (5.8%) pancolitis. According to colon involvement sites and Baron classification the results were: five (9.6 %), two (3.8%) and three (5.7%) patients with ulcerative proctitis were at grade 1, 2 and 3, respectively. Two (3.8%), six (11.5 %), six (11.5 %) and two (3.8%) patients with rectosigmoid ulcerative colitis were at grade 0, 1, 2 and 3, respectivel...