PDE4 inhibition as a therapeutic strategy for improvement of pulmonary dysfunctions in Covid-19 and cigarette smoking (original) (raw)

Corona Virus (SARS-COV-2) Induced Inflammatory Lung Disease a Review on the Role of Renin–Angiotensin System and the Angiotensin Converting Enzyme-2

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American Journal of Internal Medicine, 2020

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Cigarette smoke increases susceptibility of alveolar macrophages to SARS-CoV-2 infection through inducing reactive oxygen species-upregulated angiotensin-converting enzyme 2 expression

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A crucial role of angiotensin converting enzyme 2 (ACE2) in SARS coronavirus–induced lung injury

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The expression level of angiotensin-converting enzyme 2 determines the severity of COVID-19: lung and heart tissue as targets

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Smoking and COVID-19: Renin-Angiotensin System the Hidden Link

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INTERNATIONAL JOURNAL OF RESEARCH IN PHARMACEUTICAL SCIENCES, 2020

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Susceptibility of SARS-CoV-2 COVID-19 Infection among Smokers/Tobacco Users Upregulating the Expression of Angiotensin-Converting Enzyme-2 (ACE2

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Renin-Angiotensin System Inhibitors in COVID-19: Current Concepts

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Developing new drugs that activate the protective arm of the renin–angiotensin system as a potential treatment for respiratory failure in COVID-19 patients

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Lower Gene Expression of Angiotensin Converting Enzyme 2 Receptor in Lung Tissues of Smokers With COVID-19Pneumonia

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Inhibitors of Angiotensin-converting Enzyme or Blockers of Angiotensin-2 Receptor in COVID-19 Patients With Comorbid Cardiovascular or Pulmonary Diseases

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Angiotensin II Promotes SARS-CoV-2 Infection via Upregulation of ACE2 in Human Bronchial Cells

Marisa Brini

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Renin–angiotensin system blockade in the COVID-19 pandemic

Hossam Shaltout

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Inhibiting SARS-CoV-2 infection in vitro by suppressing its receptor, angiotensin-converting enzyme 2, via aryl-hydrocarbon receptor signal

Keiji Tanimoto

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The Lung, the Heart, the Novel Coronavirus, and the Renin-Angiotensin System; The Need for Clinical Trials

Eugenie Forbes

Frontiers in Medicine, 2020

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Angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers: potential allies in the COVID-19 pandemic instead of a threat?

Fedor Simko

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Does activation of the protective Renin-Angiotensin System have therapeutic potential in COVID-19?

Pawel Namsolleck

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Angiotensin Converting Enzyme 2 in COVID-19 infections and the implications of COVID-19 on major body systems

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Angiotensin converting enzyme 2 level and its significance in COVID‐19 and other diseases patients

Manali Dalvi

European Journal of Clinical Investigation

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The Potential Role of ACEi and ARBs in COVID-19; A Perpsective

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Angiotensin-converting enzyme 2 (ACE2) as a SARS-CoV-2 receptor: molecular mechanisms and potential therapeutic target

Arthur Slutsky

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Smoking Upregulates Angiotensin-Converting Enzyme-2 Receptor: A Potential Adhesion Site for Novel Coronavirus SARS-CoV-2 (Covid-19)

Kathryn Barnsley

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Angiotensin-Converting Enzyme 2 Roles in the Pathogenesis of COVID-19

tahereh safari

Current Hypertension Reviews, 2021

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Dysregulation of Angiotensin Converting Enzyme 2 Expression and Function in Comorbid Disease Conditions Possibly Contributes to Coronavirus Infectious Disease 2019 Complication Severity

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COVID-19 and renin-angiotensin system modulators: what do we know so far?

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The therapeutic potential of the novel angiotensin-converting enzyme 2 in the treatment of coronavirus disease-19

Adeolu Adedapo, Ademola Oyagbemi, Veterinary World

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Angiotensin-Converting-Enzyme 2 and Renin-Angiotensin System Inhibitors in COVID-19: An Update

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Role of Angiotensin Converting Enzyme-2 and its modulation in disease: exploring new frontiers

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The Cholinergic and ACE-2-Dependent Anti-Inflammatory Systems in the Lung: New Scenarios Emerging From COVID-19

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The Potential Role of Renin Angiotensin System (RAS) and Dipeptidyl Peptidase-4 (DPP-4) in COVID-19: Navigating the Uncharted

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Angiotensin-Converting Enzyme 2: SARS-CoV-2 Receptor and Regulator of the Renin-Angiotensin System

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Angiotensin-Converting-Enzyme 2 and SARS-CoV2: A Dangerous Liaison

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Renin-Angiotensin-Aldosterone System Inhibitors in COVID-19: A Review

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Hypertension and chronic obstructive pulmonary disease – current challenges during the COVID-19 pandemic

octavian istratoaie

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