On homology modeling of the M2 muscarinic acetylcholine receptor subtype (original) (raw)

Homology Modeling and Validation of the Human M1 Muscarinic Acetylcholine Receptor

Bela Viskolcz

Molecular Informatics, 2012

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Muscarinic Receptors: A Comparative Analysis of Structural Features and Binding Modes through Homology Modelling and Molecular Docking

Alessandro Pedretti

Chemistry & Biodiversity, 2006

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Toward activated homology models of the human M1 muscarinic acetylcholine receptor

Michael Buckle, David Chalmers, Elizabeth Yuriev

Journal of Molecular Graphics and Modelling, 2014

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Molecular Modeling of the M3 Acetylcholine Muscarinic Receptor and Its Binding Site

Arnau Cordomi

Journal of Biomedicine and Biotechnology, 2012

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Modelling of the binding site of the human m1 muscarinic receptor: experimental validation and refinement

Herman Schreuder

Journal of computer-aided molecular design, 1997

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Antagonist binding in the rat muscarinic receptor: A study by docking and X-ray crystallography

Brendan Howlin

2004

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Antagonist binding in the rat muscarinic receptor

José Saldanha

Computational Biology and Chemistry, 2004

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Structural insights into the subtype-selective antagonist binding to the M2 muscarinic receptor

sangbae lee

Nature Chemical Biology, 2018

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Structure and activation of muscarinic acetylcholine receptors

M Bee

Biochemical Society Transactions, 2003

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Crystal structure of the M5 muscarinic acetylcholine receptor

Celine Valant

2019

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Structure of the human M2 muscarinic acetylcholine receptor bound to an antagonist

Tetsuji Okada

Nature, 2012

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Understanding G Protein Selectivity of Muscarinic Acetylcholine Receptors Using Computational Methods

Ravi Abrol

International Journal of Molecular Sciences

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Structure-guided development of selective M3 muscarinic acetylcholine receptor antagonists

Peter Gmeiner

Proceedings of the National Academy of Sciences

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The Predicted 3D Structures of the Human M1 Muscarinic Acetylcholine Receptor with Agonist or Antagonist Bound

William Goddard

ChemMedChem, 2006

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Structure and dynamics of the full-length M1 muscarinic acetylcholine receptor studied by molecular dynamics simulations

Alessandro Pedretti

Archives of Biochemistry and Biophysics, 2008

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Evidence for a Tandem Two-site Model of Ligand Binding to Muscarinic Acetylcholine Receptors

Jan Jakubik

Journal of Biological Chemistry, 2000

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Molecular dynamics simulations of m3-muscarinic receptor activation and QSAR analysis

Maria Cristina MENZIANI

Bioorganic & Medicinal Chemistry, 1995

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Ligand-Specific Changes in M 3 Muscarinic Acetylcholine Receptor Structure Detected by a Disulfide Scanning Strategy †

Kenneth A Jacobson

Biochemistry, 2008

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Antagonist binding profiles of five cloned human muscarinic receptor subtypes

Frank Dörje

The Journal of pharmacology and experimental therapeutics, 1991

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Muscarinic Receptors as Model Targets and Antitargets forStructure-Based Ligand Discovery

Peter Gmeiner

Molecular Pharmacology, 2013

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Overproduction of human M₃ muscarinic acetylcholine receptor: an approach toward structural studies

Dasiel Oscar Borroto-Escuela

Biotechnology progress

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Comparative Molecular Field Analysis on a Set of Muscarinic Agonists

Giovanni Greco

Quantitative Structure-Activity Relationships, 1991

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Primary structure of porcine muscarinic acetylcholine receptor III and antagonist binding studies

Tai Kubo

FEBS Letters, 1988

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Conformation of Ligands Bound to the Muscarinic

T. Haga

2002

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Muscarinic receptor family interacting proteins: role in receptor function

Dasiel Oscar Borroto-Escuela

Journal of neuroscience methods, 2011

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The muscarinic M3 acetylcholine receptor exists as two differently sized complexes at the plasma membrane

Suparna Patowary 100449

Biochemical Journal, 2013

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Binding Modes and Pharmacophoric Features of Muscarinic Antagonism and  β2 Agonism (MABA) Conjugates

Anuraj Nayarisseri

Current topics in medicinal chemistry 13: 14. 1650-1655 , 2013

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Binding of N-methylscopolamine to the extracellular domain of muscarinic acetylcholine receptors

Vladimír Doležal

Scientific Reports

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The conformational and property space of acetylcholine bound to muscarinic receptors: An entropy component accounts for the subtype selectivity of acetylcholine

Alessandro Pedretti

Archives of Biochemistry and Biophysics, 2007

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Helix 8 of the M1 Muscarinic Acetylcholine Receptor: Scanning Mutagenesis Delineates a G Protein Recognition Site

José Saldanha

Molecular Pharmacology, 2011

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Agonist and Antagonist Binding of Muscarinic Acetylcholine Receptors Purified from Porcine Brain: Interconversion of High- and Low-Affinity Sites by Sulfhydryl Reagents

T. Haga

Journal of Neurochemistry, 1988

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Prediction of consensus binding mode geometries for related chemical series of positive allosteric modulators of adenosine and muscarinic acetylcholine receptors

Roger Armen

Journal of Computational Chemistry, 2017

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