Muscarinic receptor family interacting proteins: role in receptor function (original) (raw)

The muscarinic M3 acetylcholine receptor exists as two differently sized complexes at the plasma membrane

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Biochemical Journal, 2013

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Muscarinic acetylcholine receptors: novel opportunities for drug development

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Muscarinic acetylcholine receptor-interacting proteins (mAChRIPs): targeting the receptorsome

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Multiple Residues in the Second Extracellular Loop Are Critical for M3 Muscarinic Acetylcholine Receptor Activation

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Journal of Biological Chemistry, 2006

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Dissecting the conserved NPxxY motif of the M3 muscarinic acetylcholine receptor: critical role of Asp-7.49 for receptor signaling and multiprotein complex formation

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Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2011

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Impaired M3 Muscarinic Acetylcholine Receptor Signal Transduction Through Blockade of Binding of Multiple Proteins to its Third Intracellular Loop

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Cellular Physiology and Biochemistry, 2010

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Quantitative Analysis of Muscarinic Acetylcholine Receptor Homo- and Heterodimerization in Live Cells: REGULATION OF RECEPTOR DOWN-REGULATION BY HETERODIMERIZATION

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Journal of Biological Chemistry, 2005

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Molecular analysis of the regulation of muscarinic receptor expression and function

Jacques Migeon

Life Sciences, 1999

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Dissecting the Conserved NPxxY Motif of the M3 Muscarinic Acetylcholine Receptor: Critical Role of Asp-7.49 for Receptor Signaling and Multiprotein Complex Formation

Dasiel O Borroto-Escuela

Cellular Physiology and Biochemistry, 2011

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Quantitative Analysis of Muscarinic Acetylcholine Receptor Homo- and Heterodimerization in Live Cells

Juan Goin

Journal of Biological Chemistry, 2005

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Muscarinic Receptors: A Comparative Analysis of Structural Features and Binding Modes through Homology Modelling and Molecular Docking

Alessandro Pedretti

Chemistry & Biodiversity, 2006

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Structure and activation of muscarinic acetylcholine receptors

M Bee

Biochemical Society Transactions, 2003

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Overproduction of human M₃ muscarinic acetylcholine receptor: an approach toward structural studies

Dasiel Oscar Borroto-Escuela

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Ligand-Specific Changes in M 3 Muscarinic Acetylcholine Receptor Structure Detected by a Disulfide Scanning Strategy †

Kenneth A Jacobson

Biochemistry, 2008

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Activation and allosteric modulation of a muscarinic acetylcholine receptor

Peter Gmeiner

Nature, 2013

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The M5 muscarinic acetylcholine receptor third intracellular loop regulates receptor function and oligomerization

Pere Garriga Sole

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2010

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A Conserved Motif in the Membrane Proximal C-Terminal Tail of Human Muscarinic M1 Acetylcholine Receptors Affects Plasma Membrane Expression

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Journal of Pharmacology and Experimental Therapeutics, 2010

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Functional and biochemical basis for multiple muscarinic acetylcholine receptors

William Roeske

Progress in Neuro-Psychopharmacology and Biological Psychiatry, 1985

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Regulation of Muscarinic Acetylcholine Receptor Expression and Functiona

Jacques Migeon

Annals of the New York Academy of Sciences, 1995

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The role of transmembrane domain 3 in the actions of orthosteric, allosteric, and atypical agonists of the M4 muscarinic acetylcholine receptor

Christian Felder

Molecular pharmacology, 2011

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Discovery and Characterization of Orthosteric and Allosteric Muscarinic M2 Acetylcholine Receptor Ligands by Affinity Selection-Mass Spectrometry

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Journal of Biomolecular Screening, 2005

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Structure of the human M2 muscarinic acetylcholine receptor bound to an antagonist

Tetsuji Okada

Nature, 2012

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Subtype Differences in Pre-Coupling of Muscarinic Acetylcholine Receptors

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PLoS ONE, 2011

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Evidence for a Tandem Two-site Model of Ligand Binding to Muscarinic Acetylcholine Receptors

Jan Jakubik

Journal of Biological Chemistry, 2000

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Helix 8 of the M1 Muscarinic Acetylcholine Receptor: Scanning Mutagenesis Delineates a G Protein Recognition Site

José Saldanha

Molecular Pharmacology, 2011

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Reconstitution of functional muscarinic receptors by co-expression of amino- and carboxyl-terminal receptor fragments

Zvi Vogel

FEBS Letters, 1993

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Antagonist binding profiles of five cloned human muscarinic receptor subtypes

Frank Dörje

The Journal of pharmacology and experimental therapeutics, 1991

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Structural determinants of allosteric agonism and modulation at the M4 muscarinic acetylcholine receptor: identification of ligand-specific and global activation mechanisms

Katie Leach

The Journal of biological chemistry, 2010

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Discrete activation of transduction pathways associated with acetylcholine m1 receptor by several muscarinic ligands

Abraham Fisher

European Journal of Pharmacology: Molecular Pharmacology, 1994

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Muscarinic Receptors as Model Targets and Antitargets forStructure-Based Ligand Discovery

Peter Gmeiner

Molecular Pharmacology, 2013

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Affinity chromatography of the muscarinic acetylcholine receptor

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The Journal of biological chemistry, 1983

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On homology modeling of the M2 muscarinic acetylcholine receptor subtype

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Journal of Computer-Aided Molecular Design, 2013

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