Clinical experience with an antimicrobial hydrogel dressing on recalcitrant wounds (original) (raw)
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Dressings for Acute and Chronic Wounds
Archives of Dermatology, 2007
Objective: To critically review the literature on the efficacy of modern dressings in healing chronic and acute wounds by secondary intention. Data Sources: Search of 3 databases (MEDLINE, EMBASE, and the Cochrane Controlled Clinical Trials Register) from January 1990 to June 2006, completed by manual research, for articles in English and in French.
The local treatment and available dressings designed for chronic wounds
Journal of the American Academy of Dermatology, 2013
The great diversity of wounds and the broad range of available dressings complicate the selection of proper chronic wound treatment. Choosing the right treatment is the essential step in the healing process. In this review, we focus on chronic nonhealing ulcers, which are a critical problem in clinical practice, and current knowledge about persistent wound care. Here, we present the objectives of local treatment with description of several types of dressings and their ingredients, features, indications, and contraindications. These include hydrocolloid, alginate, hydrogel, and dextranomer dressings; polyurethane foam and membrane dressings; semipermeable polyurethane membrane dressings; and TenderWet (Hartmann, Rock Hill, SC) and flax dressings. There is also a brief section on the use of other alternative wound-healing accelerators, such as platelet-rich plasma and light-emitting diode therapy. ( J Am
Effects of 3 biologic dressings on healing of cutaneous
2004
Three biologic dressings [split-thickness allogeneic skin (STS)], allogeneic peritoneum (P), and xenogenic porcine small intestinal submucosa (PSIS)] were studied to determine their effects on bacterial proliferation, inflammatory reaction, vascularization, and overall healing and to compare the effects of these dressings with the effects of a nonbiologic dressing, a nonadherent synthetic pad (NASP). A medial wound (3 cm in diameter) and 2 lateral wounds (2 cm in diameter) were created at the junction of the proximal and middle thirds of each metacarpus and metatarsus in 5 horses. Each medial wound and the proximolateral wound received an STS, P, PSIS, or NASP dressing on day 8 after wounding. The other lateral wound received an NASP dressing. Bacterial proliferation, inflammatory reaction (histologic changes), and drhessing vascularization were evaluated 6 d after application of the dressing. Percentages of contraction and epithelialization, as well as healing time, were determined when the wounds had completely epithelialized. The practical applicability of the different dressings to equine wound management was also assessed. No significant difference was detected in the parameters evaluated among the treated wounds or between the treated and control wounds. The biologic dressings had no effect on infection, inflammatory response, or healing time. Vascularization was not identified in any of the biologic dressings. The PSIS and P dressings required numerous applications over the study period. The STS dressings are more practical than PSIS and P dressings owing to ease of application and stability. Thus, these biologic dressings offer no apparent advantage over a nonbiologic dressing for treatment of small granulating wounds.
Wound dressings: principles and practice
Knowledge of clinically and cost-effective wound management is an obvious requirement for surgeons, yet wound care education rarely features within the medical curriculum. As a result surgical trainees are often poorly placed to join in multidisciplinary wound management and may feel threatened when asked to manage wound complications. A vast range of dressing products exists yet robust evidence of the function and effectiveness of individual products is often lacking. An understanding of wound pathophysiology, a defined treatment goal and regular wound assessment combined with knowledge of basic wound dressing categories will provide guidance on product selection for different clinical situations and wound types.
International wound journal, 2016
The objective of this work was to evaluate the safety and effectiveness of a next-generation antimicrobial wound dressing (NGAD; AQUACEL® Ag+ Extra™ dressing) designed to manage exudate, infection and biofilm. Clinicians were requested to evaluate the NGAD within their standard protocol of care for up to 4 weeks, or as long as deemed clinically appropriate, in challenging wounds that were considered to be impeded by suspected biofilm or infection. Baseline information and post-evaluation dressing safety and effectiveness data were recorded using standardised evaluation forms. This data included wound exudate levels, wound bed appearance including suspected biofilm, wound progression, skin health and dressing usage. A total of 112 wounds from 111 patients were included in the evaluations, with a median duration of 12 months, and biofilm was suspected in over half of all wounds (54%). After the introduction of the NGAD, exudate levels had shifted from predominantly high or moderate to...
Advanced Trends in Treatment of Wounds
Current Science, 2016
There are a wide variety of dressing techniques available for the management of both acute and chronic wounds. The primary objective in both the cases is to achieve a healed wound. An ideal dressing material should accelerate wound healing and reduce loss of necessary fluids from the wound, and also help minimize pain and infection. The present trend is to promote the concept of moist wound healing. This article emphasizes on the importance of assessment of the wound, the volume of drainage fluid, amount of damage, presence of infection and location of wound for optimal wound healing.
Journal of Wound Care, 2021
A break in the integrity of the skin must be repaired as quickly as possible to avoid excess blood and fluid loss and to minimise the onset of infection. Chronic wounds, where the progression of the wound healing response is compromised, presents several challenges to healing (e.g., the presence of devitalised tissue acting as a physical barrier to healing and being a focus for bacterial contamination and the potential for subsequent infection). The objective of this article is to present, as a narrative review, the clinical evidence supporting the use of a unique hydro-responsive wound dressing (HydroClean®, HRWD1) which provides a simple treatment option that addresses a number of clinical challenges clinicians must overcome in order to facilitate wound healing progression. These studies demonstrated that this product supports successful debridement/cleansing of a wide variety of wounds, including chronic wounds, enables wound bed preparation, and leads to positive healing outcomes including in wounds that previously had failed to heal. The simplicity of using HRWD1 as a single dressing that can overcome a variety of challenges that present to the clinician when they are treating both acute and chronic wounds make it an ideal choice for a first line treatment, with the benefit of proven patient outcomes.
The effects of biological wound dressings on the healing process
Clinical materials, 1991
Three major biological dressings are available for the temporary closure of wounds: partial-thickness cadaveric human allograft skin, several forms of partial-thickness antibiotic-treated porcine xenograft skin, and human amnion. Generally, biological dressings reduce pain, close the wound to contamination and fluid loss, and prepare the wound bed for permanent closure, usually with autografts. The three types of biological dressings differ in their performance, with allograft skin being clearly superior in its wound maintenance and preparation characteristics, while porcine xenograft presents serious difficulties in incorporation into the wound bed and antigenic challenge to the recipient, and amnion is excessively fragile and tends to allow wound desiccation. The most serious potential liability of biological wound dressings is transmission of infection; however, the actual incidence of such transmission is extremely low. The advantages of physiological coverage provided by biolog...
Wound Healing Process and Wound Care Dressing: A Detailed Review
Wound care dressings aim to restore the milieu required for skin regeneration and to protect the wound from environmental thre ats and penetration of bacteria. Any single type of wound dressing can not address the need and management of all types of wound s. The availability of different types of wound dressings and research for newer type of wound dressing has increased in the la st decade. This review discusses the common and advanced wound management dressings, their key advantages and shortcomings. It also discusses the need for dressin gs with their properties in wound management. The definition and classification of wounds together with the different stages of wound healing are also briefly described. In addition to that this article also compiles the list of wound care product available in the market.