Genetic analysis of the variable region genes encoding a monospecific human natural anti-DNA antibody (original) (raw)

The normally expressed kappa immunoglobulin light chain gene repertoire and somatic mutations studied by single-sided specific polymerase chain reaction (PCR); frequent occurrence of features often assigned to autoimmunity

Torben Barington, Lars Juul

Clinical and Experimental Immunology, 1997

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Two murine natural polyreactive autoantibodies are encoded by nonmutated germ-line genes

Tuyen Do Duc

Proceedings of the National Academy of Sciences, 1989

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Immunoglobulin Variable-Region Structures in Immunity and Autoimmunity to DNA

Tony Marion

The Tohoku Journal of Experimental Medicine, 1994

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Analysis of immunoglobulin variable region genes from human IgG anti-DNA hybridomas

brian leaker

European Journal of Immunology, 1992

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Autoantibodies of various specificities encoded by genes from the VH J558 family bind to foreign antigens and share idiotopes of antibodies specific for self and foreign antigens

Noel Rose

Journal of Experimental Medicine, 1987

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Heavy chain variable gene usage by human B-1 lymphocytes and polyreactive autoantibodies

Neelima Bhat

Human Antibodies, 1997

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Unconventional B-Cell Antigens and Human Immune Repertoiresa

Gregg Silverman

Annals of the New York Academy of Sciences, 2008

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Heavy chain variable region contribution to the NPb family of antibodies: somatic mutation evident in a γ2a variable region

Thereza Imanishi-kari

Cell, 1981

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Immunoglobulin kappa light chain variable region gene complex organization and immunoglobulin genes encoding anti-DNA autoantibodies in lupus mice

A. Theofilopoulos

Journal of Clinical Investigation, 1988

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Silberstein, L. E. et al. Variable region gene analysis of pathologic human autoantibodies to the related i and I red blood cell antigens. Blood 78, 2372-2386

Jonni Moore

Blood

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The importance of somatic mutations in the Vλ gene 2a2 in human monoclonal anti-DNA antibodies

Md. Anisur Rahman Likhon

Journal of Molecular Biology, 2001

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Molecular Analysis of Human Immunoglobulin Heavy Chain Variable Genes (IgVH) in Normal and Malignant B Cells

Rizgar Mageed

The American Journal of Pathology, 1998

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Molecular characterization of the VH region of murine autoantibodies from neonatal and adult BALB/c mice

Maurizio Sollazzo

European Journal of Immunology, 1989

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The recurrent expression of variable region segments in human IgM anti-DNA autoantibodies

Harout DerSimonian

The Journal of Immunology

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Analysis of the structural heterogeneity and polymorphism of human Ia antigens. Four distinct subsets of molecules are coexpressed in the Ia pool of both DR1,1 homozygous and DR3,W6 heterozygous B cell lines

Roberto Accolla

Journal of Experimental Medicine, 1984

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Autoantibodies: Focus on anti-DNA antibodies

Inga-lill Mårtensson

Self/Nonself, 2011

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Structural characterization of antiidiotypic antibodies. Evidence that Ab2s are derived from the germline differently than Ab1s

Brian Pollok

Journal of Experimental Medicine, 1989

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The Antibody Repertoire of Early Human B Cells

Peter Lydyard

Scandinavian Journal of Immunology, 1990

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Anti-DNA autoantibodies: a puzzle of autoimmune phenomena

Yaakov Naparstek

Immunology today, 1999

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The Antibody Repertoire of Early Human B Cells I. High Frequency of Autoreactivity and Polyreactivity

Jean Jouquan

Scandinavian Journal of Immunology, 1990

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Antigenic determinants of the 70-kDa subunit of the Ku autoantigen

Mariana M Yaneva

Clinical Immunology and Immunopathology, 1992

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Expression of an anti-DNA-associated VH gene in immunized and autoimmune mice

Tony Marion

Journal of Immunology, 1997

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Molecular and serological diversity of anti-DNA autoantibodies from NZB and (NZB X NZW) F1 mice

Gretchen Kiser

1988

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Molecular and serological diversity of anti-DNA autoantibodies from NZB and (NZB × NZW) F1 mice

Mitchell Kronenberg

Immunology Letters, 1988

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Third complementarity-determining region of mutated VH immunoglobulin genes contains shorter V, D, J, P, and N components than non-mutated genes

Robert Tarone

Immunology, 2001

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Interclonal and intraclonal diversity among anti-DNA antibodies from an (NZB x NZW)F1 mouse

Tony Marion

Journal of Immunology, 1990

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The human antibody repertoire: Heavy and light chain variable region gene usage in six alloantibodies specific for human HLA class I and class II alloantigens

Stefano Mantero

Molecular Immunology, 1995

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The VH gene sequences of anti-DNA antibodies in two different strains of lupus-prone mice are highly related

Laurent Jacob

European Journal of Immunology, 1989

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Skewed V H and V K Gene Family Expression and Pairing Occurs Among B Lymphocytes in Autoimmune Motheaten Mice

Azad Kaushik

Autoimmunity, 1995

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An anti-B cell autoantibody from Wiskott-Aldrich syndrome which recognizes i blood group specificity on normal human B cells

Gregg Silverman

European Journal of Immunology, 1992

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Diversity of Ig V gene segments found in anti-DNA autoantibodies from a single (NZB x NZW)F1 mouse

Mitchell Kronenberg

The Journal of Immunology

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Both IgM and IgG anti-DNA antibodies are the products of clonally selective B cell stimulation in (NZB x NZW)F1 mice

Tony Marion

Journal of Experimental Medicine, 1992

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The Immunoglobulin V H Gene, V H 4-21, Specifically Encodes Autoanti-Red Cell Antibodies against the I or i Antigens

Graham Smith

Vox Sanguinis, 1995

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