COX-2 inhibitors: a potential target for drug therapy in the management of colorectal cancer (original) (raw)

COX-2 inhibition as a tool to treat and prevent colorectal cancer

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A Review: Role of Cyclooxygenase- 2 Inhibitors in Treatment of Colorectal Cancer

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The Relationship of Cyclooxygenase -2 (COX-2) Expression with Clinical Presentation, Staging, and Degree of Differentiation in Colorectal Cancer

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Gene modulation by Cox-1 and Cox-2 specific inhibitors in human colorectal carcinoma cancer cells

JEANELLE MARTINEZ

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The relationship between cyclooxygenase-2 expression and colorectal cancer

Ronan Conroy M Conroy, Diarmuid O'Donoghue

JAMA: The Journal of …, 1999

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Clinicopathologic significance of cyclooxygenase-2 overexpression in colorectal adenocarcinoma

Si-Hyong Jang

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Elder DJE, Halton DE, Hague A, Paraskeva CInduction of apoptotic cell death in human colorectal carcinoma cell lines by a cyclooxygenase-2 (COX-2)-selective nonsteroidal anti-inflammatory drug: independence from COX-2 protein expression. Clin Cancer Res 3: 1679-1683

Angela Hague

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Induction of apoptotic cell death in human colorectal carcinoma cell lines by a cyclooxygenase-2 (COX-2)-selective nonsteroidal anti-inflammatory drug: independence from COX-2 protein expression

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Cyclooxygenase-2 Expression: A Significant Prognostic Indicator for Patients With Colorectal Cancer

Labile Soumaoro

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Expression of Cyclooxygenase-2 (COX-2) in Colorectal Adenocarcinoma: an Immunohistochemical and Histopathological Study

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Asian Pacific Journal of Cancer Prevention, 2014

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Inhibition of human colon cancer cell growth by selective inhibition of cyclooxygenase-2

Susan Kirkland

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Cyclooxygenase-2 and Gastrointestinal Cancer

Jason Mann

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Differential expression of cyclooxygenase 2 in human colorectal cancer

Angela Ianaro

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Inhibition of haematogenous metastasis of colon cancer in mice by a selective COX-2 inhibitor, JTE-522

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Over-Expression of Cyclooxygenase-2 in Colorectal Cancer Patients

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Role of cyclooxygenase-2 in the angiogenesis of colorectal cancer

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Cyclooxygenase-2 overexpression correlates with tumour recurrence, especially haematogenous metastasis, of colorectal cancer

Eiji Sunami

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High cyclooxygenase-2 expression is associated with advanced stages in colorectal cancer

Seppo Pyrhönen

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Combined activity of COX-1 and COX-2 is increased in non-neoplastic colonic mucosa from colorectal neoplasia patients

Thorbjørn Jensen

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Cyclooxygenase-2 expression as a predictor of outcome in colorectal carcinoma

Eman Emam, Jaudah Al-maghrabi, Abdulrahman Sibiany

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Cyclooxygenase-2 Expression in Right- and Left-Sided Colon Cancer: A Rationale For Optimization of Cyclooxygenase-2 Inhibitor Therapy

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Protective Effects of Long-Term Usage of Cyclo-Oxygenase-2 Inhibitors on Colorectal Cancer in Genetically Predisposed Individuals and Their Overall Effect on Prognosis: A Systematic Review

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International Journal of Research in Pharmacy and Chemistry Role of CYCLOOXYGENASE-2 in Cancer

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Mediators of PGE2 synthesis and signalling downstream of COX-2 represent potential targets for the prevention/treatment of colorectal cancer

Abderrahmane Kadi

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Inhibitory effect of a selective cyclooxygenase-2 inhibitor on liver metastasis of colon cancer

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International Journal of Cancer, 2002

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Cancer Prevention: A New Era beyond Cyclooxygenase-2

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Regression of hepatocellular carcinoma due to cyclooxygenase (COX)-2 inhibitor

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The American journal of gastroenterology, 2006

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The cyclooxygenase-2-selective inhibitors rofecoxib and celecoxib prevent colorectal neoplasia occurrence and recurrence

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Cox-2 is needed but not sufficient for apoptosis induced by Cox-2 selective inhibitors in colon cancer cells

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Cyclooxygenase-2 inhibition in colon experimental carcinogenesis

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Nonsteroidal Anti-inflammatory Drugs and Cyclooxygenase-2 Inhibitors for Primary Prevention of Colorectal Cancer: A Systematic Review Prepared for the U.S. Preventive Services Task Force

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Annals of Internal Medicine, 2007

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Cyclooxygenase-2 (COX-2) inhibitors sensitize tumor cells specifically to death receptor-induced apoptosis independently of COX-2 inhibition

Reiner Jänicke

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