Convergent Solution Phase Synthesis of Chimeric Oligonucleotides by a 2+2 and 3+3 Phosphoramidite Strategy (original) (raw)

Solid-Phase Synthesis of Modified Oligonucleotides

Ramon Eritja

International Journal of Peptide Research and Therapeutics, 2006

View PDFchevron_right

Oligonucleotides: Current Trends and Innovative Applications in the Synthesis, Characterization, and Purification

Daniela Perrone

Biotechnology Journal, 2020

View PDFchevron_right

Simple and Efficient Solution-Phase Synthesis of Oligonucleotides Using Extractive Work-Up

m dekoning

Organic Process Research & Development, 2006

View PDFchevron_right

The Dimethoxytrityl Resin Product Anchored Sequential Synthesis Method (DMT PASS): A Conceptually Novel Approach to Oligonucleotide Synthesis

David Sebesta

Organic Process Research & Development, 2000

View PDFchevron_right

Liquid‐Phase Oligonucleotide Synthesis: Past, Present, and Future Predictions

Yogesh Sanghvi

Current protocols in nucleic acid chemistry, 2019

View PDFchevron_right

Recent Advances in Oligonucleotide Synthesis and Their Applications

Vaijayanthi Bhashyam

ChemInform, 2004

View PDFchevron_right

Recent advances in synthesis of modified oligonucleotides

Prasanta K Ghosh

Zenodo (CERN European Organization for Nuclear Research), 2000

View PDFchevron_right

Large-scale synthesis of high purity “Phos reagent” useful for oligonucleotide therapeutics

Yogesh Sanghvi

Journal of Organometallic Chemistry, 2005

View PDFchevron_right

Chemical synthesis of biologically active oligoribonucleotides using β-cyanoethyl protected ribonucleoside phosphoramidites

Christopher Francklyn, Nassim Usman

Nucleic Acids Research, 1990

View PDFchevron_right

A New Method for the Preparation of Modified Oligonucleotides

Olga Gorchs, Anna Grandas

Organic Letters, 2002

View PDFchevron_right

Prevention of guanine modification and chain cleavage during the solid phase synthesis of oligonucleotides using phosphoramidite derivatives

Nassim Usman

Nucleic Acids Research, 1986

View PDFchevron_right

Design and applications of modified oligonucleotides

Mariana Gallo

Brazilian Journal of Medical and Biological Research, 2003

View PDFchevron_right

MODIFIED OLIGONUCLEOTIDES: Synthesis and Strategy for Users

Sandeep Verma

Annual Review of Biochemistry, 1998

View PDFchevron_right

Phosphoramidites and solid supports based on N-substituted 2,4-dihydroxybutyramides: universal reagents for synthesis of modified oligonucleotides

Dmitry Stetsenko

Tetrahedron, 2006

View PDFchevron_right

Optimized Automated Solid Phase Synthesis of Oligonucleotides and Derivatives

Gerald Grübler

Zeitschrift für Naturforschung B, 1998

View PDFchevron_right

Phosphoramidite reagents and solid-phase supports based on hydroxyprolinol for the synthesis of modified oligonucleotides

Sergey Gontarev

Russian Journal of Bioorganic Chemistry, 2017

View PDFchevron_right

Large scale, liquid phase oligonucleotide synthesis by alkyl H-phosphonate approach

Kamlesh Padiya

Bioorganic & Medicinal Chemistry, 2000

View PDFchevron_right

Synthesis of Chimeric Oligonucleotides Containing Phosphodiester, Phosphorothioate, and Phosphoramidate Linkages

Andrei Guzaev

Organic Letters, 2000

View PDFchevron_right

A facile route to 3′-modified oligonucleotides

Dmitry Stetsenko

Bioorganic & Medicinal Chemistry Letters, 1997

View PDFchevron_right

Reagents for the preparation of two oligonucleotides per synthesis (TOPSTM)

Andrew Garman

Nucleic Acids Research, 1994

View PDFchevron_right

UnyLinker: An Efficient and Scaleable Synthesis of Oligonucleotides Utilizing a Universal Linker Molecule: A Novel Approach To Enhance the Purity of Drugs

LUCIO MENDEZ

Organic Process Research & Development, 2008

View PDFchevron_right

Solid-phase synthesis of base-sensitive oligonucleotides

Pasi Virta

Arkivoc, 2008

View PDFchevron_right

A new and versatile reagent for incorporating multiple primary aliphatic amines into synthetic oligonucleotides

Roy Leon

Nucleic Acids Research, 1989

View PDFchevron_right

Oligonucleotide synthesis using the manual phosphotriester method

william donnelly

Methods in molecular biology (Clifton, N.J.), 1988

View PDFchevron_right

3′-3′-linked oligonucleotides: Synthesis and stability studies

Carole Chaix

Bioorganic & Medicinal Chemistry Letters, 1996

View PDFchevron_right

Oligonucleotides make sensible strides

Graeme Doran

Drug Discovery Today, 2004

View PDFchevron_right

Synthesis and triple helix-forming ability of oligonucleotides with N,N-dimethylaminoethyl phosphoramidate linkages

Anna Grandas

Tetrahedron Letters, 1999

View PDFchevron_right

In vitro and in vivo properties of therapeutic oligonucleotides containing non-chiral 3′ and 5′ thiophosphate linkages

Erich Koller

Nucleic Acids Research, 2019

View PDFchevron_right

Automated parallel synthesis of 5′-triphosphate oligonucleotides and preparation of chemically modified 5′-triphosphate small interfering RNA

Sarfraz Shaikh, Ivan Zlatev, Ligang Zhang

Bioorganic & Medicinal Chemistry, 2013

View PDFchevron_right