Prevention of guanine modification and chain cleavage during the solid phase synthesis of oligonucleotides using phosphoramidite derivatives (original ) (raw )Synthesis of Oligodeoxynucleotides Containing 2-Substituted Guanine Derivatives Using 2-Fluoro-2'-Deoxyinosine as Common Nucleoside Precursor
Ramon Eritja
Nucleos Nucleot Nucleic Acids, 1997
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Synthesis of modified oligonucleotides containing 4-guanidino-2-pyrimidinone nucleobases
Anna Grandas
Tetrahedron, 2001
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A New Method for the Preparation of Modified Oligonucleotides
Olga Gorchs , Anna Grandas
Organic Letters, 2002
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Phosphoramidites and solid supports based on N-substituted 2,4-dihydroxybutyramides: universal reagents for synthesis of modified oligonucleotides
Dmitry Stetsenko
Tetrahedron, 2006
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Synthesis of oligodeoxynucleotides containing 6-N-([13C]methyl)adenine and 2-N-([13C]methyl)guanine
Ramon Eritja
J Chem Soc Perkin Trans 1, 1997
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Synthesis of oligonucleotides containing bulky adducts at guanine N2 via the phosphoramidite of O2-triflate-O6-NPE 2′-deoxyxanthosine
Richard Hodge
Tetrahedron Letters, 2000
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Solid-Phase Synthesis of Modified Oligonucleotides
Ramon Eritja
International Journal of Peptide Research and Therapeutics, 2006
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Phosphoramidite reagents and solid-phase supports based on hydroxyprolinol for the synthesis of modified oligonucleotides
Sergey Gontarev
Russian Journal of Bioorganic Chemistry, 2017
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Chemical synthesis of biologically active oligoribonucleotides using β-cyanoethyl protected ribonucleoside phosphoramidites
Christopher Francklyn , Nassim Usman
Nucleic Acids Research, 1990
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Duplex-Stabilization Properties of Oligodeoxynucleotides Containing N2-Substituted Guanine Derivatives
Ramon Eritja
Helvetica Chimica Acta, 2000
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Efficient guanidination of the phosphate linkage towards cationic phosphoramidate oligonucleotides
Françoise Debart
Tetrahedron Letters, 2003
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Nucleoside 3'-phosphotriesters as key intermediates for the oligoribonucleotide synthesis. IV. New method for removal of 2,2,2-trichioroethyl group and 31 NMR as a new tool for analysis of deblocking of intemucleotide phosphate protecting groups
Wojciech Markiewicz , Julia Seegers
Nucleic Acids Research, 1977
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Fast oligonucleotide deprotection phosphoramidite chemistry for DNA synthesis
Huynh Vu
Tetrahedron Letters, 1990
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SolidPhase synthesis of positively charged deoxynucleic guanidine (DNG) oligonucleotide mixed sequences
Mallikarjuna Reddy
Bioorganic & Medicinal Chemistry Letters, 2003
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The 4-( N -Dichloroacetyl- N -methylamino)benzyloxymethyl Group for 2‘Hydroxyl Protection of Ribonucleosides in the SolidPhase Synthesis of Oligoribonucleotides
jon duff
Journal of Organic Chemistry, 2008
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Nucleoside 3'phosphotriesters as key intermediates for the oligoribonucleotide synthesis. III. An improved preparation of nucleoside 3'-phosphotriesters, their 1H NMR characterization and new conditions for removal of 2-cyanoethyl group
Wojciech Markiewicz
Nucleic Acids Research, 1976
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Solid-phase synthesis of base-sensitive oligonucleotides
Pasi Virta
Arkivoc, 2008
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MODIFIED OLIGONUCLEOTIDES: Synthesis and Strategy for Users
Sandeep Verma
Annual Review of Biochemistry, 1998
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Synthesis and triple helix-forming ability of oligonucleotides with N,N-dimethylaminoethyl phosphoramidate linkages
Anna Grandas
Tetrahedron Letters, 1999
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Improved strategies for postoligomerization synthesis of oligodeoxynucleotides bearing structurally defined adducts at the N 2 position of deoxyguanosine
dimitrios tsarouhtsis
Chemical research …, 1996
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3′-3′-linked oligonucleotides: Synthesis and stability studies
Carole Chaix
Bioorganic & Medicinal Chemistry Letters, 1996
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Further studies on oligoribonucleotide synthesis
Wojciech Markiewicz
Nucleic Acids Symposium Series
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The use of labile base protecting groups in oligoribonucleotide synthesis
Carole Chaix
Tetrahedron Letters, 1989
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Phosphotriester approach to the synthesis of oligonucleotides: a reappraisal
Colin Reese
Journal of the Chemical Society, Perkin Transactions 1, 1993
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A new approach to the synthesis of oligonucleotides and their phosphorothioate analogues in solution
Quanlai Song , Colin Reese
Bioorganic & Medicinal Chemistry Letters, 1997
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Synthesis, biophysical properties, and nuclease resistance properties of mixed backbone oligodeoxynucleotides containing cationic internucleoside guanidinium linkages: Deoxynucleic guanidine/DNA chimeras
Dinesh Barawkar
Proceedings of the National Academy of Sciences, 1998
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Synthesis of Chimeric Oligonucleotides Containing Phosphodiester, Phosphorothioate, and Phosphoramidate Linkages
Andrei Guzaev
Organic Letters, 2000
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Synthesis of 2‘-O-[2-[(N,N-Dimethylamino)oxy]ethyl] Modified Nucleosides and Oligonucleotides
Guillermo Vasquez
The Journal of Organic Chemistry, 2002
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2‘- O -[2-(Guanidinium)ethyl]-Modified Oligonucleotides: Stabilizing Effect on Duplex and Triplex Structures †
Thazha Prakash
Organic Letters, 2004
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N-(2-Hydroxyethyl)phenazinium derivatives of oligonucleotides as effectors of the sequence-specific modification of nucleic acids with reactive oligonucleotide derivatives
Olga Fedorova
FEBS Letters, 1988
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Selective O-phosphitilation with nucleoside phosphoramidite reagents
Sergei Gryaznov
Nucleic Acids Research, 1992
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Synthesis of 2′- N -Methylamino-2′-deoxyguanosine and 2′- N , N -Dimethylamino-2′-deoxyguanosine and Their Incorporation into RNA by Phosphoramidite Chemistry
Qing Dai
The Journal of Organic Chemistry, 2011
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ChemInform Abstract: Oligonucleotides Bearing Cationic Groups: N2-(3-Aminopropyl) deoxyguanosine. Synthesis, Enhanced Binding Properties and Conjugation Chemistry
Dan Cook
Cheminform, 2010
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A Comparative Study of Supports for the Synthesis of Oligonucleotides Without Using Ammonia
Anna Aviñó
Nucleosides and Nucleotides, 1996
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Diastereomers of a mono-substituted phosphoryl guanidine trideoxyribonucleotide: Isolation and properties
Dmitry Stetsenko
Biochemical and Biophysical Research Communications, 2019
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