A common dominant TLR5 stop codon polymorphism abolishes flagellin signaling and is associated with susceptibility to legionnaires' disease (original) (raw)

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Flagellin expression enhances Salmonella accumulation in TLR5-positive macrophages

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Flagellin is critical for Legionella motility and macrophage recognition

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Blocking of the TLR5 Activation Domain Hampers Protective Potential of Flagellin DNA Vaccine

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Mucosal Administration of Flagellin Protects Mice from Streptococcus pneumoniae Lung Infection

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TLR5-deficient mice lack basal inflammatory and metabolic defects but exhibit impaired CD4 T cell responses to a flagellated pathogen

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Silent recognition of flagellins from human gut commensal bacteria by Toll-like receptor 5

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Cytosolic recognition of flagellin by mouse macrophages restricts Legionella pneumophila infection

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TLR5 functions as an endocytic receptor to enhance flagellin‐specific adaptive immunity

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Bacterial flagellin elicits widespread innate immune defense mechanisms, apoptotic signaling, and a sepsis-like systemic inflammatory response in mice

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2010

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Effects of flagellin on innate and adaptive immunity

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2005

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Activation of NLRC4 downregulates TLR5-mediated antibody immune responses against flagellin

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