A common dominant TLR5 stop codon polymorphism abolishes flagellin signaling and is associated with susceptibility to legionnaires' disease (original ) (raw )Involvement of Toll-like receptor 5 in the recognition of flagellated bacteria
Philippe Pagni
Proceedings of the National Academy of Sciences, 2006
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Cutting edge: bacterial flagellin activates basolaterally expressed TLR5 to induce epithelial proinflammatory gene expression
Tony Navas
The Journal of …, 2001
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Toll-like receptor 5 recognizes a conserved site on flagellin required for protofilament formation and bacterial motility
kelly smith
Nature Immunology, 2003
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Evasion of Toll-like receptor 5 by flagellated bacteria
Kelly Smith
Proceedings of The National Academy of Sciences, 2005
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Flagellin/TLR5 responses in epithelia reveal intertwined activation of inflammatory and apoptotic pathways
P. Lin , Andrew Neish
AJP: Gastrointestinal and Liver Physiology, 2005
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Mucosal interplay among commensal and pathogenic bacteria: lessons from flagellin and Toll-like receptor 5
M. Rumbo
FEBS letters, 2006
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Identification of Conserved Domains in Salmonella muenchen Flagellin That Are Essential for Its Ability to Activate TLR5 and to Induce an Inflammatory Response in Vitro
Kanneganti Murthy
Journal of Biological Chemistry, 2003
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Sublingual flagellin protects against acute pneumococcal pneumonia in a TLR5-dependent and NLRC4-independent fashion
Analía Rial
Future Microbiology, 2016
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Role of Toll-like receptor 2 in recognition of Legionella pneumophila in a murine pneumonia model
Shoji Kudoh
Journal of Medical Microbiology, 2007
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Human Airway Epithelial Cells Sense Pseudomonas aeruginosa Infection via Recognition of Flagellin by Toll-Like Receptor 5
Daniel Weiner
Infection and Immunity, 2005
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Toll‐Like Receptor 4 Is Not Involved in Host Defense against Pulmonary Legionella pneumophila Infection in a Mouse Model
Peter Speelman
The Journal of Infectious Diseases, 2002
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Activation of Toll-Like Receptors by Live Gram-Negative Bacterial Pathogens Reveals Mitigation of TLR4 Responses and Activation of TLR5 by Flagella
David Fetterer
Frontiers in Cellular and Infection Microbiology, 2021
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Flagellin expression enhances Salmonella accumulation in TLR5-positive macrophages
Dirk Werling
Developmental & Comparative Immunology, 2010
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Flagellin is critical for Legionella motility and macrophage recognition
Natalie Whitfield
2009
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Blocking of the TLR5 Activation Domain Hampers Protective Potential of Flagellin DNA Vaccine
Sukumar Saha
The Journal of Immunology, 2007
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Mucosal Administration of Flagellin Protects Mice from Streptococcus pneumoniae Lung Infection
Analía Rial
Infection and Immunity, 2010
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Flagellin-independent effects of a Toll-like receptor 5 polymorphism in the inflammatory response to Burkholderia pseudomallei
Sudeshna Seal
PLOS Neglected Tropical Diseases, 2019
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Toll-Like Receptor 9 Regulates the Lung Macrophage Phenotype and Host Immunity in Murine Pneumonia Caused by Legionella pneumophila
Cory Hogaboam
Infection and Immunity, 2008
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TLR5-deficient mice lack basal inflammatory and metabolic defects but exhibit impaired CD4 T cell responses to a flagellated pathogen
Shaikh Atif
The Journal of …, 2011
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Silent recognition of flagellins from human gut commensal bacteria by Toll-like receptor 5
youssef belkhadir
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Interleukin 1 receptor-driven neutrophil recruitment accounts to MyD88-dependent pulmonary clearance of legionella pneumophila infection in vivo
Juliana Hori
The Journal of infectious diseases, 2015
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Bacterial flagellins: mediators of pathogenicity and host immune responses in mucosa
M. Rumbo
Trends in microbiology, 2004
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Toll-like receptor 2 and its roles in immune responses against Legionella pneumophila
Dr.A. Kariminik
Life Sciences, 2017
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Flagellin-induced tolerance of the Toll-like receptor 5 signaling pathway in polarized intestinal epithelial cells
James Madara
AJP: Gastrointestinal and Liver Physiology, 2006
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The Role of Flagellin versus Motility in Acute Lung Disease Caused byPseudomonas aeruginosa
Reuben Ramphal
The Journal of Infectious Diseases, 2007
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Cytosolic recognition of flagellin by mouse macrophages restricts Legionella pneumophila infection
Ari Molofsky
Journal of Experimental Medicine, 2006
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TLR5 functions as an endocytic receptor to enhance flagellin‐specific adaptive immunity
Shaikh Atif
European journal of …, 2011
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Comparative Genomics Reveal That Host-Innate Immune Responses Influence the Clinical Prevalence of Legionella pneumophila Serogroups
Mohammad Ali Khan , Natalie Knox
PLoS ONE, 2013
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Bacterial flagellin elicits widespread innate immune defense mechanisms, apoptotic signaling, and a sepsis-like systemic inflammatory response in mice
Noureddine Loukili
2010
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Effects of flagellin on innate and adaptive immunity
Steven Mizel
2005
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Activation of NLRC4 downregulates TLR5-mediated antibody immune responses against flagellin
Huimin Yan
Cellular and Molecular Immunology, 2015
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