Hepatic cytochrome P450 activity, abundance, and expression throughout human development (original) (raw)

Systematic genetic and genomic analysis of cytochrome P450 enzyme activities in human liver

Eugene Chudin

Genome Research, 2010

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Determination of major human cytochrome P450s activities in 96-well plates using liquid chromatography tandem mass spectrometry

Jose Castell

Toxicology in Vitro, 2007

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Assessment of Cytochrome P450 Induction in Human Hepatocytes Using the Cocktail Strategy Plus Liquid Chromatography Tandem Mass Spectrometry

Jose Castell

Drug Metabolism Letters, 2008

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Regulation of drug-metabolizing human cytochrome P450s

Katalin Monostory

Acta Chimica Slovenica, 2008

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Simultaneous measurement of 23 isoforms from the human cytochrome P450 families 1-3 by quantitative RT-PCR

Isabelle de Waziers

Drug Metabolism and Disposition, 2005

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Discerning Relationships Among Human Cytochrome P450s by Computational Analyses

Rajeev Soni, Kulvinder Saini

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A cocktail approach for assessing the in vitro activity of human cytochrome P450s: An overview of current methodologies

Youssef Daali

Journal of Pharmaceutical and Biomedical Analysis, 2014

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Unlocking the Clinical Significance of Cytochrome P450 Enzymes

Dr. Rajesh B Hadia

International journal of pharmaceutical investigation, 2023

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Microsomal cytochrome P450 as a target for drug discovery and repurposing

Ayman El-Kadi

Drug Metabolism Reviews, 2016

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Concise review of the cytochrome P450s and their roles in toxicology

Rory Remmel

Toxicological Sciences, 1999

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Cytochrome P450 Part 1: Multiplicity and Function

Ross McKinnon

Journal of Pharmacy Practice and Research, 2008

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Evaluation of Time-Dependent Cytochrome P450 Inhibition Using Cultured Human Hepatocytes

Ken Grime, Amanda Berry

Drug Metabolism and Disposition, 2006

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Constitutive expression of hepatic cytochrome P450 genes

Ying-Hue Lee

The FASEB Journal, 1996

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Human cytochromes P450

J. Capdevila

Molecular Aspects of Medicine, 1999

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Use of inhibitory monoclonal antibodies to assess the contribution of cytochromes P450 to human drug metabolism

Tin-tin Lu

European Journal of Pharmacology, 2000

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Mechanism-Based Inactivation of Human Cytochromes P450s: Experimental Characterization, Reactive Intermediates, and Clinical Implications

Ute Kent

Chemical Research in Toxicology, 2007

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Cytochrome P450 induction in rat hepatocytes assessed by quantitative real-time reverse-transcription polymerase chain reaction and the RNA invasive cleavage assay

Robert A Zivin, Michael Burczynski

Drug metabolism and disposition: the biological fate of chemicals, 2001

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The pharmacology of the cytochrome P450 enzyme system

Munir Pirmohamed

1998

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A rapid ultra-performance liquid chromatography/tandem mass spectrometric methodology for the in vitro analysis of Pooled and Cocktail cytochrome P450 assays

Darcy Shave

Rapid Communications in Mass Spectrometry, 2010

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Inhibition and induction of human cytochrome P450 enzymes: current status

Paavo Honkakoski

Archives of Toxicology, 2008

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Mass spectrometry-based absolute quantification of microsomal cytochrome P450 2D6 in human liver

Helmut E. Meyer

PROTEOMICS, 2009

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Application of Slicing of One-Dimensional Gels with Subsequent Slice-by-Slice Mass Spectrometry for the Proteomic Profiling of Human Liver Cytochromes P450

Herbert Thiele

Journal of Proteome Research, 2010

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The role of cytochrome P450 enzymes in hepatic and extrahepatic human drug toxicity

Munir Pirmohamed

Pharmacology & Therapeutics, 1995

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Pharmacogenomics of human liver cytochrome P450 oxidoreductase: multifactorial analysis and impact on microsomal drug oxidation

Kathrin Klein

Pharmacogenomics, 2009

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Methodological Approaches to Cytochrome P450 Profiling in Embryos

John Stegeman

Methods in molecular biology, 2012

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Cross-species analysis of hepatic cytochrome P450 and transport protein expression

Oliver Poetz

Archives of Toxicology, 2020

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An extensive cocktail approach for rapid risk assessment of in vitro CYP450 direct reversible inhibition by xenobiotic exposure

Youssef Daali

Toxicology and applied pharmacology, 2016

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Interindividual Variance of Cytochrome P450 Forms in Human Hepatic Microsomes: Correlation of Individual Forms with Xenobiotic Metabolism and Implications in Risk Assessment

John Snawder

Regulatory Toxicology and Pharmacology, 2000

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Cytochromes P450: a success story

Daniele Werck-reichhart

Genome Biol, 2000

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Modern approaches for the phenotyping of cytochrome P450 enzymes in children

Youssef Daali

Expert Review of Clinical Pharmacology, 2020

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Associate editor: H. Bönisch Cytochrome P450 enzymes in drug metabolism: Regulation of gene expression, enzyme activities, and impact of genetic variation

天鹏 张

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Molecular modeling of mammalian cytochrome P450s

Fred Friedman

2000

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Rational Development of Novel Activity Probes for the Analysis of Human Cytochromes P450

Hamza Abumansour

ChemMedChem, 2016

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