Cross-species analysis of hepatic cytochrome P450 and transport protein expression (original) (raw)

Estimation of Drug-Metabolizing Capacity by Cytochrome P450 Genotyping and Expression

Journal of Pharmacology and Experimental Therapeutics, 2012

Estimation of Fraction Metabolized by Cytochrome P450 Enzymes Using Long-Term Cocultured Human Hepatocytes

Drug Metabolism and Disposition

Associate editor: H. Bönisch Cytochrome P450 enzymes in drug metabolism: Regulation of gene expression, enzyme activities, and impact of genetic variation

天鹏张

View PDFchevron_right

Functional pharmacogenetics/genomics of human cytochromes P450 involved in drug biotransformation

Kathrin Klein

Analytical and Bioanalytical Chemistry, 2008

View PDFchevron_right

Direct Quantification of Cytochromes P450 and Drug Transporters-A Rapid, Targeted Mass Spectrometry-Based Immunoassay Panel for Tissues and Cell Culture Lysates

Thomas O Joos

Drug metabolism and disposition: the biological fate of chemicals, 2018

View PDFchevron_right

Functional Consequences of Active Hepatic Uptake on Cytochrome P450 Inhibition in Rat and Human Hepatocytes

Ken Grime

Drug Metabolism and Disposition, 2008

View PDFchevron_right

Evidence of Significant Contribution from CYP3A5 to Hepatic Drug Metabolism

Weili Huang

Drug Metabolism and Disposition, 2004

View PDFchevron_right

Assessment of Cytochrome P450 Induction in Human Hepatocytes Using the Cocktail Strategy Plus Liquid Chromatography Tandem Mass Spectrometry

Jose Castell

Drug Metabolism Letters, 2008

View PDFchevron_right

Drug metabolism by CYP2C8.3 is determined by substrate dependent interactions with cytochrome P450 reductase and cytochrome b5

Rheem Totah

Biochemical Pharmacology, 2011

View PDFchevron_right

The role of cytochrome P450 enzymes in hepatic and extrahepatic human drug toxicity

Munir Pirmohamed

Pharmacology & Therapeutics, 1995

View PDFchevron_right

Cytochrome P450 – Role In Drug Metabolism And Genetic Polymorphism

Anitha Rajan

2018

View PDFchevron_right

Metabolomics reveals biomarkers in human urine and plasma to predict cytochrome P450 2D6 (CYP2D6) activity

Youssef Daali

British Journal of Pharmacology, 2021

View PDFchevron_right

Pharmacogenomics of human liver cytochrome P450 oxidoreductase: multifactorial analysis and impact on microsomal drug oxidation

Kathrin Klein

Pharmacogenomics, 2009

View PDFchevron_right

Enzyme-Based Amperometric Platform to Determine the Polymorphic Response in Drug Metabolism by Cytochromes P450

Gianfranco Gilardi

Analytical Chemistry, 2011

View PDFchevron_right

Quantitative Proteomics of Clinically Relevant Drug-Metabolizing Enzymes and Drug Transporters and Their Inter-correlations in the Human Small Intestine

Narciso Couto

Drug Metabolism and Disposition

View PDFchevron_right

Systematic genetic and genomic analysis of cytochrome P450 enzyme activities in human liver

C. Suver

Genome Research, 2010

View PDFchevron_right

Influence of Proteome Profiles and Intracellular Drug Exposure on Differences in CYP Activity in Donor-Matched Human Liver Microsomes and Hepatocytes

Jozef Urdzik

Molecular Pharmaceutics

View PDFchevron_right

How useful is the 'cocktail approach' for evaluating human hepatic drug metabolizing capacity using cytochrome P450 phenotyping probes in vivo?

Nori Kurata

Journal of Clinical Pharmacy and Therapeutics, 2003

View PDFchevron_right

Editorial: Precision Medicine: Impact of Cytochromes P450 and Transporters Genetic Polymorphisms, Drug-Drug Interactions, Disease on Safety and Efficacy of Drugs

Youssef Daali

Frontiers in Pharmacology, 2022

View PDFchevron_right

Interindividual Variance of Cytochrome P450 Forms in Human Hepatic Microsomes: Correlation of Individual Forms with Xenobiotic Metabolism and Implications in Risk Assessment

John Snawder

Regulatory Toxicology and Pharmacology, 2000

View PDFchevron_right

Microarray Analysis of Differentially- Expressed Genes Encoding CYP450 and Phase II Drug Metabolizing Enzymes in

Venil N Sumantran

View PDFchevron_right

Determination of Cytochrome P450 Metabolic Activity Using Selective Markers

Alexandra Sulcova

Topics on Drug Metabolism, 2012

View PDFchevron_right

Pharmacogenomics of the cytochrome P450 2C family: impacts of amino acid variations on drug metabolism

adriana isvoran

Drug Discovery Today, 2017

View PDFchevron_right

Use of inhibitory monoclonal antibodies to assess the contribution of cytochromes P450 to human drug metabolism

Tin-tin Lu

European Journal of Pharmacology, 2000

View PDFchevron_right

Cytochrome P450 2D6: overview and update on pharmacology, genetics, biochemistry

Sebastian Raimundo

Naunyn-Schmiedeberg's Archives of Pharmacology, 2004

View PDFchevron_right

Hepatic cytochrome P450 activity, abundance, and expression throughout human development

Natalie Sadler

Drug metabolism and disposition: the biological fate of chemicals, 2016

View PDFchevron_right

Pharmacogenomic Role in Cytochrome P450 Enzymes-Mediated Metabolism for Drug Therapy

Linawati Hananta

Journal of Urban Health Research

View PDFchevron_right

Xenobiotic-Induced Transcriptional Regulation of Xenobiotic Metabolizing Enzymes of the Cytochrome P450 Superfamily in Human Extrahepatic Tissues

Bentham Science Publishers

Current Drug Metabolism

View PDFchevron_right

System-Dependent Metabolism of Drugs by Cytochrome P450: The Mechanistic Basis for Why Human Liver Microsomes Are Superior to Human Hepatocytes at Metabolizing Midazolam but Inferior at Metabolizing Desloratadine

Faraz Kazmi

2015

View PDFchevron_right

Cytochromes P450 and experimental models of drug metabolism

Eva Anzenbacherova

Journal of Cellular and Molecular Medicine, 2002

View PDFchevron_right

Identification of human cytochrome P 450 s that metabolise anti-parasitic drugs and predictions of in vivo drug hepatic clearance from in vitro data

Mna Hih

European Journal of Clinical Pharmacology, 2003

View PDFchevron_right

Cross-species analysis of hepatic cytochrome P450 and transport protein expression (original) (raw)

Related papers