Abnormal, error-prone bypass of photoproducts by xeroderma pigmentosum variant cell extracts results in extreme strand bias for the kinds of mutations induced by UV light (original) (raw)

Mutation research, 1996

Evidence that in Xeroderma Pigmentosum Variant Cells, which Lack DNA Polymerase , DNA Polymerase Causes the Very High Frequency and Unique Spectrum of UV-Induced Mutations

Cancer Research, 2007

Characteristics of UV-induced Mutation Spectra in Human XP-D/ERCC2 Gene-mutated Xeroderma Pigmentosum and Trichothiodystrophy Cells

Journal of Molecular Biology, 1995

Mutation of xeroderma pigmentosum lymphoblasts by far-ultraviolet light

Debra Kaden

Mutation research, 1984

DNA strand specificity for UV-induced mutations in mammalian cells

Nicole Groen

Molecular and cellular biology, 1989

Sunlight-induced cancer: some new aspects and implications of the xeroderma pigmentosum model

Bryn Bridges

British Journal of Dermatology, 1990

Whole-exome sequencing reveals the impact of UVA light mutagenesis in xeroderma pigmentosum variant human cells

Natália Moreno

Nucleic Acids Research

Xeroderma Pigmentosum Fibroblasts Including Cells from XP Variants Are Abnormally Sensitive to the Mutagenic and Cytotoxic Action of Broad Spectrum Simulated Sunlight

Photochemistry and Photobiology, 1984

Reconstruction of DNA Repair-deficient Xeroderma Pigmentosum Skin In Vitro: A Model to Study Hypersensitivity to UV Light¶

Photochem Photobiol, 2007

Increased UV resistance in xeroderma pigmentosum group A cells after transformation with a human genomic DNA clone

Ari Rinaldy

Proceedings of the National Academy of Sciences, 1990

Mutations induced by ultraviolet light

Gerd P Pfeifer

Mutation research, 2005

Expression of a mammalian DNA photolyase confers light-dependent repair activity and reduces mutations of UV-irradiated shuttle vectors in xeroderma pigmentosum cells

Takeshi Todo

Mutation Research/DNA Repair, 1999

Increased ultraviolet sensitivity and chromosomal instability related to P53 function in the xeroderma pigmentosum variant

Hatsumi Nagasawa, J. Cleaver

Cancer research, 1999

DNA Single-Strand Breaks during Repair of UV Damage in Human Fibroblasts and Abnormalities of Repair in Xeroderma Pigmentosum

kurt kohn

Proceedings of The National Academy of Sciences, 1976

UV-induced mutations in a shuttle vector replicated in repair deficient trichothiodystrophy cells differ with those in genetically-related cancer prone xeroderma pigmentosum

Carcinogenesis, 1993

Different removal of ultraviolet photoproducts in genetically related xeroderma pigmentosum and trichothiodystrophy diseases

Xavier Quilliet

Cancer research, 1995

Increased UV resistance of a xeroderma pigmentosum revertant cell line is correlated with selective repair of the transcribed strand of an expressed gene

Philip Hanawalt

Molecular and cellular biology, 1993

Comparative study of nucleotide excision repair defects between XPD-mutated fibroblasts derived from trichothiodystrophy and xeroderma pigmentosum patients

DNA Repair, 2008

Photoproduct frequency is not the major determinant of UV base substitution hot spots or cold spots in human cells

Saras Wathy

Proceedings of the …, 1987

Xeroderma pigmentosum variant cells are less likely than normal cells to incorporate dAMP opposite photoproducts during replication of UV-irradiated plasmids

Proceedings of the National Academy of Sciences, 1991

UV wavelength-dependent DNA damage and human non-melanoma and melanoma skin cancer

Gerd P Pfeifer

Photochemical & Photobiological Sciences, 2012

Differential behaviors toward ultraviolet A and B radiation of fibroblasts and keratinocytes from normal and DNA-repair-deficient patients

Cancer research, 1999

Cytogenetic evidence for differences in DNA incision activity in xeroderma pigmentosum group A, C and D cells after X-irradiation during G2 phase

Robert Tarone

Mutation Research/DNA Repair, 1993

Ultraviolet light-induced chromosomal aberrations in cultured cells from Cockayne syndrome and complementation group C xeroderma pigmentosum patients: lack of correlation with cancer susceptibility

Robert Tarone

American journal of human genetics, 1988

The key role of UVA-light induced oxidative stress in human Xeroderma Pigmentosum Variant cells

Veridiana Munford

Free Radical Biology and Medicine, 2018

Mutagenic specificity of solar UV light in nucleotide excision repair-deficient rodent cells

Emmanuel BRULAY

Proceedings of the National Academy of Sciences, 1996

Strand specificity for UV-induced DNA repair and mutations in the Chinese hamster HPRT gene

Paola Menichini

Nucleic Acids Research, 1991

DNA repair defect in xeroderma pigmentosum group C and complementing factor from HeLa cells

Mahmud K . K . Shivji

Journal of Biological Chemistry, 1994

Deficiency in the Nuclease Activity of Xeroderma Pigmentosum G in Mice Leads to Hypersensitivity to UV Irradiation

Reiko Shinkura

Molecular and Cellular Biology, 2004

Molecular and cellular analysis of the DNA repair defect in a patient in Xeroderma pigmentosum complementation group D who has the clinical features of Xeroderma pigmentosum and Cockayne syndrome

Miria Stefanini

The American Journal of Human Genetics, 1995

Ultraviolet light-induced sister chromatid exchanges in xeroderma pigmentosum and in Cockayne's syndrome lymphocyte cell lines

Robert Tarone

Cancer research, 1978

Ultraviolet light-resistant primary transfectants of xeroderma pigmentosum cells are also DNA repair-proficient

Dan Canaani

Biochemical and Biophysical Research Communications, 1989

CC to TT mutation in the mitochondrial DNA of normal skin: relationship to ultraviolet light exposure

Takayoshi Suzuki

Mutation Research/Genetic Toxicology and Environmental Mutagenesis, 2000

Ultraviolet-induced chromosomal instability in cultured fibroblasts of heterozygote carriers for xeroderma pigmentosum

Michael Weichenthal

Cancer Genetics and Cytogenetics, 1989

DNA excision-repair processes in human cells can eliminate the cytotoxic and mutagenic consequences of ultraviolet irradiation

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, 1979