Whole-exome sequencing reveals the impact of UVA light mutagenesis in xeroderma pigmentosum variant human cells (original) (raw)
The key role of UVA-light induced oxidative stress in human Xeroderma Pigmentosum Variant cells
Veridiana Munford
Free Radical Biology and Medicine, 2018
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Unravelling UVA-induced mutagenesis
Stefania Francesconi
Photochemical & Photobiological Sciences, 2012
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Characteristics of UV-induced Mutation Spectra in Human XP-D/ERCC2 Gene-mutated Xeroderma Pigmentosum and Trichothiodystrophy Cells
Alain Sarasin
Journal of Molecular Biology, 1995
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The relative roles of DNA damage induced by UVA irradiation in human cells
Annabel Quinet
Photochemical & Photobiological Sciences, 2013
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UV wavelength-dependent DNA damage and human non-melanoma and melanoma skin cancer
Gerd P Pfeifer
Photochemical & Photobiological Sciences, 2012
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Mutations induced by ultraviolet light
Gerd P Pfeifer
Mutation research, 2005
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UVA induces persistent genomic instability in human keratinocytes through an oxidative stress mechanism
Trevor McMillan
Free Radical Biology and Medicine, 2002
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Abnormal, error-prone bypass of photoproducts by xeroderma pigmentosum variant cell extracts results in extreme strand bias for the kinds of mutations induced by UV light
Justin McCormick
Molecular and cellular biology, 1999
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Evidence that in Xeroderma Pigmentosum Variant Cells, which Lack DNA Polymerase , DNA Polymerase Causes the Very High Frequency and Unique Spectrum of UV-Induced Mutations
Justin McCormick
Cancer Research, 2007
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Multiplex PCR Analysis of Ultraviolet A and B Induced Delayed and Early Mutations in V79 Chinese Hamster Cells
Jostein Dahle
Photochemistry and Photobiology, 2004
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Multiplex Polymerase Chain Reaction Analysis of UVA– and UV-B–induced Delayed and Early Mutations in V79 Chinese Hamster Cells
Jostein Dahle
Photochemistry and Photobiology, 2005
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Cyclobutane pyrimidine dimers are predominant DNA lesions in whole human skin exposed to UVA radiation
Jean Cadet
Proceedings of the National Academy of Sciences, 2006
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The mutagenic effect of ultraviolet‐A1 on human skin demonstrated by sequencing the p53 gene in single keratinocytes
Fredrik Pontén, Cecilia Williams
Photodermatology, …, 2002
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Murine melanomas accelerated by a single UVR exposure carry photoproduct footprints but lack UV signature C>T mutations in critical genes
Herlina Handoko
Oncogene, 2015
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Murine melanomas accelerated by a single UVR exposure carry photoproduct footprints but lack UV signature C>T mutations in critical genes
Herlina Handoko
Oncogene, 2015
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Report Transcription-Dependent Cytosine Deamination Is a Novel Mechanism in Ultraviolet Light-Induced Mutagenesis
Niels Wind
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DNA strand specificity for UV-induced mutations in mammalian cells
Nicole Groen
Molecular and cellular biology, 1989
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DNA excision-repair processes in human cells can eliminate the cytotoxic and mutagenic consequences of ultraviolet irradiation
Justin McCormick
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, 1979
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Mutation of xeroderma pigmentosum lymphoblasts by far-ultraviolet light
Debra Kaden
Mutation research, 1984
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Comparison of the rate of excision of major UV photoproducts in the strands of the human HPRT gene of normal and xeroderma pigmentosum variant cells
Justin McCormick
Mutation research, 1996
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Induction of oxidative DNA base damage in human skin cells by UV and near visible radiation
Rex Tyrrell
Carcinogenesis, 1997
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Transcription-Dependent Cytosine Deamination Is a Novel Mechanism in Ultraviolet Light-Induced Mutagenesis
Niels Wind
Current Biology, 2010
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The specificity of UV-induced mutations at an endogenous locus in mammalian cells
Barry Glickman
Proceedings of the National Academy of Sciences, 1987
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Xeroderma Pigmentosum Fibroblasts Including Cells from XP Variants Are Abnormally Sensitive to the Mutagenic and Cytotoxic Action of Broad Spectrum Simulated Sunlight
Justin McCormick
Photochemistry and Photobiology, 1984
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Bystander effects in UV-induced genomic instability: Antioxidants inhibit delayed mutagenesis induced by ultraviolet A and B radiation
Jostein Dahle
Journal of Carcinogenesis, 2005
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p53 suppression overwhelms DNA polymerase η deficiency in determining the cellular UV DNA damage response
James Cleaver
DNA Repair, 2007
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Mutagenic specificity of solar UV light in nucleotide excision repair-deficient rodent cells
Emmanuel BRULAY
Proceedings of the National Academy of Sciences, 1996
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Features of Uvr and Uv-Induced Mutagenesis
David E Fisher
2014
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Mutagenic action of monochromatic UV radiation in the solar range on human cells
Rex Tyrrell
Mutation research, 1984
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Application of UV-Induced Unscheduled DNA-Synthesis Measurements in Human Genotoxicological Risk Assessment
Anna Tompa
DNA Repair and Human Health, 2011
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Oxidatively-generated damage to DNA and proteins mediated by photosensitized UVA
Reto Brem
Free Radical Biology and Medicine
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Deficiency in the Nuclease Activity of Xeroderma Pigmentosum G in Mice Leads to Hypersensitivity to UV Irradiation
Reiko Shinkura
Molecular and Cellular Biology, 2004
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Bipyrimidine Photoproducts Rather than Oxidative Lesions Are the Main Type of DNA Damage Involved in the Genotoxic Effect of Solar UVA Radiation †
Jean Cadet
Biochemistry, 2003
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The formation of DNA single-strand breaks and alkali-labile sites in human blood lymphocytes exposed to 365-nm UVA radiation
Dmitry Klokov
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Defective Global Genome Repair in XPC Mice Is Associated with Skin Cancer Susceptibility But Not with Sensitivity to UVB Induced Erythema and Edema
Frank De Gruijl
Journal of Investigative Dermatology, 1998
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