In vitro non-rigid life-size model of aortic arch aneurysm for endovascular prosthesis assessment (original) (raw)
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In Vitro, Nonrigid Model of Aortic Arch Aneurysm
Journal of Vascular and Interventional Radiology, 2008
PURPOSE: To develop and validate a controlled patient-derived process for producing an in vitro, nonrigid model of aortic arch aneurysm. MATERIALS AND METHODS: A three-dimensional magnetic resonance (MR) angiogram derived from a patient with an aortic arch aneurysm was segmented by using a homemade software package, meshed and converted to Standard Tessellation Language (STL) file format. The authors transferred this format to a stereolithography machine to produce a replica of the entire aorta, including the arch aneurysm and supraaortic arteries, by pouring silicone rubber. RESULTS: A sturdy, life-size, soft, transparent plastic cast, accurately reproducing both the internal and external anatomy of the aortic aneurysm, was produced in less than 1 week. Comparison between the STL file format of MR angiographic images of both the patient's aorta and model enabled validation of the reliability of the manufacturing process. CONCLUSIONS: The combination of easy segmentation and conversion to the STL file format with stereolithography techniques enabled a realistic, life-size, silicone vascular phantom to be created from a live patient imaging dataset.
Abstract 14097: A 3D Print Low Cost Aortic Arch Endovascular Simulator
Circulation, 2020
Introduction: Simulation-based medical teaching and learning enables trainees to gain competencies in a realistic setting without imposing risks to patients. Within endovascular training, simulations improve patient safety and decrease health care costs. Access of the aortic arch from a femoral puncture site is a key competency in the endovascular field. Here, we show how a low-cost artificial vascular simulator enables accurate replicated catheterization of the aortic arch. Hypothesis: Methods: Digital Imaging and Communications in Medicine (DICOM) data extracted from a computed-angio tomograph (CTA) using an image processing software was selected to include the arterial region of interest. A mold was made with plastisol from the printed 3D toolpath (Fig. 1). After maturation of the mold, the separate sections were assembled into the simulator (Fig. 2). Results: Data extracted from a CTA was processed to create a vascular model that was accessed using an arterial access kit, and gu...
Modelling of aortic aneurysm and aortic dissection through 3D printing
Journal of medical radiation sciences, 2017
The aim of this study was to assess if the complex anatomy of aortic aneurysm and aortic dissection can be accurately reproduced from a contrast-enhanced computed tomography (CT) scan into a three-dimensional (3D) printed model. Contrast-enhanced cardiac CT scans from two patients were post-processed and produced as 3D printed thoracic aorta models of aortic aneurysm and aortic dissection. The transverse diameter was measured at five anatomical landmarks for both models, compared across three stages: the original contrast-enhanced CT images, the stereolithography (STL) format computerised model prepared for 3D printing and the contrast-enhanced CT of the 3D printed model. For the model with aortic dissection, measurements of the true and false lumen were taken and compared at two points on the descending aorta. Three-dimensional printed models were generated with strong and flexible plastic material with successful replication of anatomical details of aortic structures and pathologi...
Scientific Reports, 2016
Patient-specific vascular replicas are essential to the simulation of endovascular treatment or for vascular research. The inside of silicone replica is required to be smooth for manipulating interventional devices without resistance. In this report, we demonstrate the fabrication of patient-specific silicone vessels with a low-cost desktop 3D printer. We show that the surface of an acrylonitrile butadiene styrene (ABS) model printed by the 3D printer can be smoothed by a single dipping in ABS solvent in a time-dependent manner, where a short dip has less effect on the shape of the model. The vascular mold is coated with transparent silicone and then the ABS mold is dissolved after the silicone is cured. Interventional devices can pass through the inside of the smoothed silicone vessel with lower pushing force compared to the vessel without smoothing. The material cost and time required to fabricate the silicone vessel is about USD $2 and 24 h, which is much lower than the current fabrication methods. This fast and low-cost method offers the possibility of testing strategies before attempting particularly difficult cases, while improving the training of endovascular therapy, enabling the trialing of new devices, and broadening the scope of vascular research.
3D Reconstruction of Aortic Aneurysms for the Design of Personalized Endoluminal Protheses
Advances in endoluminal treatment, which have highly reduced risks in aneurysm treatment, can only be widely disseminated through the use of computational techniques supporting more objective aneurysmatic pathology quantification. Due to patients´ anatomical variations, there exists an evident necessity of specific software tools to perform the vascular pathology measurement from tomographic volumes, enabling better prosthesis design. We present a method for the automated detection, 3D reconstruction and measurement of aortic aneurysmatic pathologies, which enables the automated generation of data that can be used fo the design of personalized endoluminal prostheses. This method is integrated into a tool that can access DICOM standard image databases and also share 3D reconstruction results through the internet as virtual reality representations.
Modeling and visualization techniques for virtual stenting of aneurysms and stenoses
Computerized Medical Imaging and Graphics, 2012
In this work, we present modeling and visualization techniques for virtual stenting of aneurysms and stenoses. In particular, contributions to support the computer-aided treatment of artery diseases-artery enlargement (aneurysm) and artery contraction (stenosis)-are made. If an intervention takes place, there are two different treatment alternatives for this kind of artery diseases: open surgery and minimally invasive (endovascular) treatment. Computer-assisted optimization of endovascular treatments is the main focus of our work. In addition to stent simulation techniques, we also present a computer-aided simulation of endoluminal catheters to support the therapy-planning phase. The stent simulation is based on a three-dimensional Active Contour Method and is applicable to both non-bifurcated (I-stents) and bifurcated stents (Y-stents). All methods are introduced in detail and are evaluated with phantom datasets as well as with real patient data from the clinical routine. Additionally, the clinical prototype that is based upon these methods is described.
Journal of Vascular Surgery, 2019
Conclusions: The material of all tested covered stents has withstood the flaring forces without damage of the PTFE fabric or stent fracture. Pullout force was highest in the BeGraft Plus, followed by VBX, BeGraft, and Advanta V12, but the slope of the pullout force at the first part was highest in the Advanta V12 stent, followed by BeGraft Plus, VBX, and BeGraft. The ability to withstand crushing forces was highest in Advanta and BeGraft Plus, followed by VBX and BeGraft. These findings together with the special features of the tested stents should have an important implication for clinical practice. Fatigue tests for these stents in this special indication are mandatory to ave a dedicated bridging stent graft for fenestrated aortic repair in the future.
Functional 3D printed patient-specific modeling of severe aortic stenosis
Journal of the American College of Cardiology, 2014
Computed tomography (CT) provides high-resolution images of the aortic valve with clear localization of calcium deposition. Three-dimensional (3D) stereolithographic printing can be used to convert these data into a physical model (1,2). We hypothesized that patient-specific, multimaterial, 3D printed models REPLY: Is it Time to Launch
Silicone models of the aortic root to plan and simulate interventions
Interactive CardioVascular and Thoracic Surgery, 2020
OBJECTIVES The objective of this work was to develop technology to create ‘soft’ patient-specific models of semilunar heart valves, the aortic valve in particular, suitable for training and simulation of surgical and endovascular interventions. METHODS Data obtained during routine cardiac contrast-enhanced multislice computed tomography were used to create 3-dimensional models of the aortic root. Three-dimensional models were used to create soft silicone models of the aortic root made by casting silicone into a negative mould printed with stereolithography. A comparison between the constructed models and the size of the aortic root was performed. We quantified how much time was needed for production of each model. RESULTS Four patient-specific soft models of the aortic root were produced. Data from patients of different ages and body surface areas were used as prototypes. All models had minimum size errors. During development of this technology, production time per model was reduced...