Investigation of the human metabolism of antipyrine using coupled liquid chromatography and nuclear magnetic resonance spectroscopy of urine
Jeremy Nicholson
Journal of Chromatography B: Biomedical Sciences and Applications, 1993
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Quantitative determination of antipyrine and its metabolites in urine by the method of microcolumn HPLC
Sergey I . Kolesnikov
Pharmaceutical Chemistry Journal, 1989
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Rate of drug metabolism in man measured by 14 CO 2 -breath analysis
Johannes Bircher
European Journal of Clinical Pharmacology, 1978
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Metabolism of drugs and carcinogens in man: Antipyrine elimination as an indicator
Kamala Krishnaswamy
Clinical Pharmacology & Therapeutics, 1979
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Liquid chromatography-mass spectrometry method for the analysis of 1,4-dimethylpyridinium in rat plasma - application to pharmacokinetic studies
Kamil Kus
Biomedical Chromatography, 2013
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Using mass spectrometry for drug metabolism studies
Ragu Ramanathan, W. Korfmacher
Journal of the American Society for Mass Spectrometry, 2006
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Application of Liquid Chromatography-Accelerator Mass Spectrometry (LC-AMS) to Evaluate the Metabolic Profiles of a Drug Candidate in Human Urine and Plasma
Larry Tremaine
Drug Metabolism Letters, 2007
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Application of Stable Isotope Methodology in the Evaluation of the Pharmacokinetics of (S,S)-3-[3-(Methylsulfonyl)phenyl]-1-propylpiperidine Hydrochloride in Rats
Diana MELO ROMERO
Drug Metabolism and Disposition, 2009
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Toxicological determination and in vitro metabolism of the designer drug methylenedioxypyrovalerone (MPDV) by gas chromatography/mass spectrometry and liquid chromatography/quadrupole time-of-flight mass spectrometry
Xavier de la Torre
Rapid Communications in Mass Spectrometry, 2010
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Application of amperometric detection to the high-performance liquid chromatographic determination of antipyrine and 4-aminoantipyrine in urine
Vera Pacakova
Journal of Chromatography A, 1988
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Experiments for a systematic comparison between stable-isotope-(deuterium) labeling and radio-(14C) labeling for the elucidation of the in vitro metabolic pattern of pharmaceutical drugs
Goetz Schlotterbeck
Journal of Pharmaceutical and Biomedical Analysis, 2013
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Stable Isotope- and Mass Spectrometry-based Metabolomics as Tools in Drug Metabolism: A Study Expanding Tempol Pharmacology
X pang
Journal of Proteome Research, 2013
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Sensitive method for the quantification of urinary pyrimidine metabolites in healthy adults by gas chromatography–tandem mass spectrometry
Thomas Mürdter
Journal of Chromatography B, 2003
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Implementing tandem mass spectrometry as a routine tool for characterizing the complete purine and pyrimidine metabolic profile in urine samples
Elisabetta Pasquini
Journal of Mass Spectrometry, 2006
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Disposition and Metabolic Profiling of [14C]Cerlapirdine Using Accelerator Mass Spectrometry
Mark Seymour
Drug Metabolism and Disposition, 2014
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Application of stable isotope methodology to study the pharmacokinetics, bioavailability and metabolism of nitrendipine after i.v. and p.o. administration
M. Eichelbaum
British Journal of Clinical Pharmacology, 1987
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Gas Chromatography. Mass Spectrometry Analysis of 2-Amino-1-Methyl-6-Phenylimidazo[4,5-b]Pyridine in Urine and Feces
Marlin Friesen
Environmental Health Perspectives, 1993
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Isotope ratio mass spectrometry in antidoping analysis: The use of endogenous reference compounds
Xavier de la Torre
Rapid Communications in Mass Spectrometry, 2019
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Applications of stable isotopes in clinical pharmacology
Herman Woerdenbag, Henderik Frijlink
British Journal of Clinical Pharmacology, 2011
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Assessment of antipyrine kinetics from saliva or plasma: influence of age
Javier González-Gallego
Journal of Pharmaceutical and Biomedical Analysis, 1995
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Analytical strategy to investigate 3,4-methylenedioxypyrovalerone (MDPV) metabolites in consumers’ urine by high-resolution mass spectrometry
María Ibáñez
Analytical and Bioanalytical Chemistry, 2015
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DRUG METABOLISM- CLINICAL PHARMACOLOGY
magendira mani vinayagam
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Relationship between in vivo and in vitro drug metabolism in man
Jorma Ahokas
European Journal of Drug Metabolism and Pharmacokinetics, 1978
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Gas chromatography/negative ion chemical ionization mass spectrometry and liquid chromatography/electrospray ionization tandem mass spectrometry quantitative profiling ofN-acetylcysteine conjugates of valproic acid in urine: application in drug metabolism studies in humans
Kevin Farrell
Journal of Mass Spectrometry, 2000
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Effect of deltamethrin on antipyrine pharmacokinetics and metabolism in rat
Arturo Anadón
Archives of Toxicology, 1991
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Comparison between external and internal standard calibration in the validation of an analytical method for 1-hydroxypyrene in human urine by high-performance liquid chromatography/tandem mass spectrometry
Paolo Faranda
Rapid Communications in Mass Spectrometry, 2006
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Pharmacokinetics and metabolism of N-(2-hydroxyethyl)-2,5-[14C]-pyrrolidine (HEP, Epolamine) in male healthy volunteers
Barbara Palumbo
European Journal of Drug Metabolism and Pharmacokinetics, 1996
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Determination of arylamines and aminopyridines in pharmaceutical products using in-situ derivatization and liquid chromatography–mass spectrometry
Emmie Dumont
Journal of Chromatography A, 2009
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Aminopyrine disposition: A sensitive index of acetaminophen-induced hepatocellular damage
gershon hepner
Toxicology and Applied Pharmacology, 1978
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Accuracy of the one-sample method for determination of antipyrine clearance in elderly subjects
Javier González-Gallego
Journal of Pharmaceutical and Biomedical Analysis, 1996
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Pharmacokinetic parameters of antipyrine in dog after hepatectomy
David Fabre
Biopharmaceutics & Drug Disposition, 1995
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In-vitro metabolism of isotetrandrine, a bisbenzylisoquinoline alkaloid, in rat hepatic S9 fraction by high-performance liquid chromatography–atmospheric pressure ionization mass spectrometry
Sashi Gopaul
Journal of Pharmacy and Pharmacology, 2004
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Characterization of xylazine metabolism in rat liver microsomes using liquid chromatography-hybrid triple quadrupole-linear ion trap-mass spectrometry.
P Vachon
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1 Analytical Strategy to Investigate 3 , 4-METHYLENEDIO Xypyrovalerone ( MDPV ) Metabolites in Consumers ’ Urine by High Reso Lution Mass Spectrometry
María Ibáñez
2015
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A Validated Liquid Chromatography/Tandem Mass Spectrometry Assay for cis -Amminedichloro(2-methylpyridine)platinum(II) in Human Plasma Ultrafiltrate
Soumyajit Das
Analytical Chemistry, 2002
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