Screening of 34 Indian medicinal plants for antibacterial properties (original) (raw)
Related papers
Antibacterial activity of some folklore medicinal plants used by tribals in Western Ghats of India
Journal of Ethnopharmacology, 2000
A series of 30 Indian folklore medicinal plants used by tribal healers to treat infections, were screened for antibacterial properties at 10 mg/ml concentration by using disc diffusion method against Bacillus subtilis, Escherichia coli, Klebsiella aerogenes, Proteus 6ulgaris, Pseudomonas aerogenes and Staphylococcus aureus. Twenty plant species showed activity against one or more species of bacteria used in this assay; among them the leaf extracts of Cassia occidentalis and Cassia auriculata exhibited significant broad spectrum activity against B. subtilis and S. aureus. Ten plant species were not found active against all tested bacteria. These results were compared with results obtained using standard antibiotics, chloramphenicol (30 vg/disc) and streptomycin (30 vg/disc) which served as a reference for inhibition zone diameter
Ethnic tribes and medicinal plans Jaipur: …, 2010
Bacterial pathogens have evolved numerous defense mechanisms against antimicrobial agents; hence resistance to old and newly produced drugs is on the rise. The phenomenon of antibiotic resistance exhibited by the pathogenic microorganisms have led to the need for screening of several medicinal plants for their potential antimicrobial activity. Thus the present study was undertaken to investigate the antibacterial activity of 15 medicinal plants used by tribals against UTI causing isolates. The antibacterial activity of aqueous, ethanol and acetone extracts of Corriander sativum, Abutilon indicum, Boerhavia diffusa andrographis paniculata, Plantago ovata, Bacopa monnieri, Bauhinia variegata, Flacouratia ramontchi, Embelia tfgerium, Euphorbia ligularia, Zinziber officinale, Terminalia chebula, Azadirachta indica, Ocimum sanctum and Cinnamomum cassia was determined against 33 UTI isolates i.e. Proteus mirabilis (10), Escherichia coli (6), Proteus vulgaris (6), Klebsiella pneumoniae (5), Enterobacter cloacae (2), Providencia pseudomallei (2), Pseudomonas aeruginosa (1) and Klebsiella oxytoca (1) by disc diffusion method. Our studies concluded that crude extracts of the selected plants especially the acetone and ethanol extracts exhibited significant activity against UTI pathogens. It can be concluded that these plants can be used to discover natural products that may serve as lead for the development of new pharmaceuticals addressing the major therapeutic needs.
India has rich heritage of using medicinal plants in traditional medicines such as Ayurveda, Siddha, and Unani besides folklore practices. The aim of the present study was to evaluate the antimicrobial activity of different plant extracts. The antimicrobial activities of some plant species (Phyllanthus emblica, Tinospora cordifolia, Eclipta alba, and Cassia occidentalis) extracts were evaluated against four bacterial strains (Staphylococcus aureus, Enterococcus faecalis, Pseudomonas aeruginosa, and Escherichia coli) by the disc diffusion method. Phyllanthus emblica and T. cordifolia had better activity against all the tested organisms compared to other plant extract fractions. Aqueous fraction of C. occidentalis and P. emblica showed high activity against P. aeruginosa and S. aureus bacteria. n-Hexane fraction of T. cordifolia showed high activity against E. coli (162 ml/g), P. aeruginosa (162 ml/g), and S. aureus (162 ml/g) bacteria.
Screening of some Indian medicinal plants for their antimicrobial properties
Journal of Ethnopharmacology, 1998
A total of 82 Indian medicinal plants traditionally used in medicines were subjected to preliminary antibacterial screening against several pathogenic and opportunistic microorganisms. Aqueous, hexane and alcoholic extracts of each plant were tested for their antibacterial activity using agar well diffusion method at sample concentration of 200 mg/ml. The results indicated that out of 82 plants, 56 exhibited antibacterial activity against one or more test pathogens. Interestingly, extracts of five plants showed strong and broad spectrum activity as compared to rest of 51 plant extracts which demonstrated moderate activity. On the whole the alcoholic extracts showed greater activity than their corresponding aqueous and hexane extracts. Among various extracts, only alcoholic extracts of Emblica officinalis, Terminalia chebula, Terminalia belerica, Plumbago zeylanica and Holarrhena antidysenterica were found to show potentially interesting activity against test bacteria. These active crude alcoholic extracts were also assayed for cellular toxicity to fresh sheep erythrocytes and found to have no cellular toxicity.
The Pharma Innovation Journal, 2019
Evaluation of phytochemical analysis and antibacterial activity of few medicinal plants collected from nearby area of Junagadh, Gujarat, India was carried out. Presence of phytochemicals in different types of extracts (chloroform, alcoholic and aqueous) was evaluated as per standard chemical methods. All extracts were evaluated for having antibacterial action using disc diffusion assay with selected bacterial cultures. Out of 16 medicinal plants methanolic extract of Adansonia digitata L. leaves showed a zone of inhibition against Klebsiella pneumoniae (20.02±0.08 mm) and Salmonella typhi (20.69±0.08 mm). Methanol and water extracts of Ficus racemosa L. bark showed a zone of inhibition of 18.48±0.02 mm and 19.68±0.03 mm, respectively against Escherichia coli. Whereas chloroform and methanol extracts of Pueraria tuberosa (Willd.) DC tuber has showed a zone of inhibition of 20.68±0.03 mm and 19.73±0.3 mm, respectively against Klebsiella pneumoniae and Streptococcus agalactiae. Phytoch...
International Journal of Advanced Research (IJAR), 2019
Ethanolic and aqueous extracts of 10 Indian medicinal plants traditionally used in medicine at Vidisha district were studied for their antimicrobial activity against human pathogenic bacteria of clinical origin. Of these, 09 ethanolic extracts and 08 aqueous extracts of medicinal plant showed varied levels of antibacterial activity against one or more tested human pathogenic bacterial strains. Overall, broad-spectrum antibacterial activity was observed in 05 Indian medicinal plants (both ethanolic and aqueous extracts) against all test microorganisms (Staphylococcus aureus, Bacillus subtilis, Escherichia coli, Salmonella typhi and Streptococcus pneumoniae).
Antibacterial Activities of Some Folk Medicinal Plants of Eastern Ghats
Antibacterial activity in the crude extracts of the selected parts (roots/ leaves/ fruits/ seeds/ bark) of different traditional folk medicinal plants of North Coastal Andhra Pradesh was examined. Of the 14 plants studied only 10 plants showed various levels of antibacterial activity against Gram positive (Bacillus subtilis, Staphylococcus aureus) and Gram negative (Escherichia coli, Klesbsiella pneumonia & Proteus vulgaris) bacteria with the diameters of growth inhibition zone in the range of 10–25mm. However, Abelmoschus moschatus (Fabaceae), Thespesia populnea (Malvaceae), Abutilon indicum (Malvaceae) and Amaranthus spinosis (Amaranthaceae) have not shown any antimicrobial activity in the extracts with solvents such as methanol, 95% ethyl alcohol and methanol: chloroform: water (MCW – 12:5:3) mixture. Eclipta prostrata (Compositae), which is used as folk medicine, showed antibacterial activity only in the ethyl alcohol extract of its leaves. Present studies indicate that the ten plants, which showed antibacterial activity, may be used as good sources for the isolation of the active principle(s) for therapeutic applications.
Antibacterial activity of some Indian medicinal plants
Aqueous extracts of ten medicinal plants were examined for their antibacterial potential against some reference strains of human pathogenic bacteria. Anethum graveolens, Elettaria cardamomum, Foeniculum vulgare, Trachyspermum ammi and Viola odorata were found to be better/equally effective compared to standard antibiotics. V. odorata was the most effective antibacterial with minimum inhibitory concentration values ranging from 1 to 2%. The results provide a scientific basis for the centuries-old usage of aqueous extracts of these medicinal plants.
Antibacterial and phytochemical studies on twelve species of Indian medicinal plants
The aqueous and methanol extracts of 12 plants each belonging to different families were evaluated for antibacterial activity against medically important bacteria viz. B. cereus ATCC11778 , S. epidermidids ATCC12228 , E. aerogenes ATCC13048, P. vulgaris NCTC 8313, S. typhimurium ATCC 23564. The in vitro antibacterial activity was performed by agar disc diffusion and agar well diffusion method. The aqueous extracts were inactive but methanol extracts showed some degree of antibacterial activity against the tested bacterial strains. S. typhimurium was the most resistant bacteria while B. cereus was the most susceptible bacteria. Amongst the plant species screened, methanol extract of Bauhinia variegata bark showed best antibacterial activity. (Afr. J. Biomed. Res. 10: 175 -181)