Synthesis and biological properties of β-turned Aβ 31–35 constrained analogues (original) (raw)

Preparation and Structure ofβ-Peptides Consisting of Geminally Disubstitutedβ2,2- andβ3,3-Amino Acids: A Turn Motif forβ-Peptides

Stefan Abele

Helvetica Chimica Acta, 1998

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Synthesis and conformational studies of α/β2,3-peptides derived from alternating β2,3-amino acids and L-Ala repeats

sridhar tailor, Ajit Kunwar

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The Structural Characterization of Folded Peptides Containing the Conformationally Constrained β -Amino Acid Residue β 2,2 Ac 6 c

Krishnayan Basuroy

Helvetica Chimica Acta, 2012

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Peptide with built-in conformational constraints: structure of Z-(Aib) 7 -O t Bu

Michael Kokkinidis

Acta Crystallographica Section B Structural Science, 1993

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Effect of d-amino acids at Asp 23 and Ser 26 residues on the conformational preference of Aβ 20–29 peptides

Balázs Majer

Biochemical and Biophysical Research Communications, 2005

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Design of peptides with α,β-dehydro residues: pseudo-tripeptide N -benzyloxycarbonyl–ΔLeu– L -Ala– L -Leu–OCH 3

Sharmistha Dey

Acta Crystallographica Section C Crystal Structure Communications, 2002

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Three-Residue Turns in α/β-Peptides and Their Application in the Design of Tertiary Structures

Chandramouli Nagula

Chemistry – An Asian Journal, 2008

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Solid state and solution conformations of a hybrid αγααγα hexapeptide. Characterization of a backbone expanded analog of the α-polypeptide 310-helix

S. Raghothama

Biopolymers, 2008

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The preferred solid‐state conformation of (αMe) Trp peptides

Roberto Fattorusso, Ornella Maglio, Marco Crisma

1995

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Compatibility of .beta.- and .gamma.-turn features with a peptide backbone modification: synthesis and conformational analysis of a model cyclic pseudopentapeptide

Mohmed Anwer, Lila Gierasch

Journal of the American Chemical Society, 1986

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Pleated Sheets and Turns ofβ-Peptides with Proteinogenic Side Chains

Stefan Abele

Angewandte Chemie International Edition, 1999

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Preferred conformation of the terminally blocked (Aib)10 homo-oligopeptide: A long, regular 310-helix

Marco Crisma

Biopolymers, 1991

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Nonstereogenic α-aminoisobutyryl -glycyl dipeptidyl unit nucleates type l' β-turn in linear peptide in aqueous solution

Larry Masterson

Biopolymers, 2007

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Molecular Conformation and Packing of Peptide β Hairpins in the Solid State: Structures of Two Synthetic Octapeptides Containing 1-Aminocycloalkane-1Carboxylic Acid Residues at thei+2 Position of the β Turn

Rajkishor Rai

Chemistry-a European Journal, 2005

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Small and Simple, yet Sturdy: Conformationally Constrained Peptides with Remarkable Properties

Krištof Bozovičar

International Journal of Molecular Sciences

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Synthesis and Conformational Analysis of Cyclotetrapeptide Mimetic β-Turn Templates and Validation as 3D Scaffolds

Eusebio Juaristi

ChemMedChem, 2009

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Design of bioactive and structurally well-defined peptides from conformationally restricted libraries

Antonio Ferrer

Biopolymers, 2004

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Collateral Existence of Folded and Extended Conformations of the β-Ala Moiety in a Model Peptide

Paloth Venugopalan

Biochemical and Biophysical Research Communications, 2000

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Peptide β-Bend and 3 10-Helix: from 3D-Structural Studies to Applications as Templates

Marco Crisma

Journal of Inclusion Phenomena, 2005

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Linear oligopeptides. 273. Structural versatility of peptides from C.alpha.,.alpha.-disubstituted glycines. Synthesis, characterization, and solution conformational analysis of homopeptides from C.alpha.-methyl-C.alpha.-benzylglycine, and [(.alpha.Me)Phe]n1

Marco Crisma

Macromolecules, 1993

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Solid-phase synthesis ofC-terminally modified peptides

Mark Damen

Journal of Peptide Science, 2006

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Crystal-state 3D-structural characterization of novel, Aib-based, turn and helical peptides

Marta De Zotti

Journal of Peptide Science, 2007

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Designed Peptides with Homochiral and Heterochiral Diproline Templates as Conformational Constraints

Rajkishor Rai

Chemistry-a European Journal, 2008

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Nonstereogenic α‐aminoisobutyryl‐glycyl dipeptidyl unit nucleates type I′ β‐turn in linear peptides in aqueous solution

Larry R . Masterson, George Barany

Peptide …, 2007

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Linear oligopeptides. 81. Solid-state and solution conformation of homooligo(.alpha.-aminoisobutyric acids) from tripeptide to pentapeptide: evidence for a 310 helix

Marco Crisma

Journal of the American Chemical Society, 1982

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Cyclopentapeptides as Flexible Conformational Templates

Katalin Kövér, Garland Marshall

Journal of the American Chemical Society, 2000

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Synthesis of Enantiopure 7-Substituted Azepane-2-carboxylic Acids as Templates for Conformationally Constrained Peptidomimetics

Giuseppe Bifulco, Manuela Rodriquez

European Journal of Organic Chemistry, 2012

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The paradox of conformational constraint in the design of Cbl(TKB)-binding peptides

Chia-en Chang, Smitha Kizhake, Carol Kolar

Scientific Reports, 2013

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α,β hybrid peptides: A polypeptide helix with a central segment containing two consecutive β-amino acid residues

Rituparna Sinha Roy

Proceedings of the National Academy of Sciences, 2004

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β 2 -Amino Acids in the Design of Conformationally Homogeneous c yclo -Peptide Scaffolds

Per Arvidsson

The Journal of Organic Chemistry, 2006

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Solid-phase synthesis of C-terminal modified peptides

Dennis W. P. M. Löwik

Biopolymers, 2003

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Rigid Linkers for Bioactive Peptides

Josef Vagner

Bioconjugate Chemistry, 2006

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Rational design of complementary peptides to the βAmyloid 29–42 fusion peptide: An application of PepDesign

Robert Brasseur

Biochimica et Biophysica Acta (BBA) - Biomembranes, 2006

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