A Phenethyl bromo ester from Citharexylum fruticosum (original) (raw)
Related papers
2002
Do extrato hexânico da casca do caule de Bombacopsis glabra (Bombacaceae) foram isolados a flavona 5-hidroxi-3,6,7,8,4'-pentametoxiflavona (1) e os triterpenos lupenona, 9,19-ciclolanost-23-eno-3β,25-diol (2), (24R)-9,19-ciclolanost-25-eno-3β,24-diol (3) e (24S)-9,19-ciclolanost-25eno-3β,24-diol (4). As estruturas foram determinadas por espectroscopia de RMN de 13 C e de 1 H (1D e 2D) e EM, e ainda, por comparação com dados da literatura para os triterpenos. A confirmação inequívoca da estrutura da flavona 1 foi realizada por um estudo de difração de raios X. As cinco substâncias foram isoladas pela primeira vez de espécies de Bombacaceae. The flavone 5-hydroxy-3,6,7,8,4'-pentamethoxyflavone (1) and the triterpenes lupenone, 9,19cyclolanost-23-ene-3β,25-diol (2), (24R)-9,19-cyclolanost-25-ene-3β,24-diol (3) and (24S)-9,19cyclolanost-25-ene-3β,24-diol (4) were isolated from the hexane extract of the stem bark of Bombacopsis glabra (Bombacaceae). The structures were determined by 13 C and 1 H NMR (1D and 2D) and mass spectrometry, and by comparison with literature data for triterpenes. The structure of the flavone 1 was unambiguously confirmed by a X-ray diffraction study. The five substances were isolated for the first time from Bombacaceae species.
Two new phytosterols from the stem bark of Ficus bengalensis L
Phytochemical investigation of the methanolic extract of the stem bark of Ficus bengalensis L. (Moraceae) resulted in the isolation of two new phytoconstituents characterized as lanost-5,24-dien-3b-yl-b-D-glucopyranosid-2 0-O-yl-docos-11 00-enoate (lanostadienylglucosyl cetoleate) (1) and 3b-acetoxy-stigmast-22-en-26-oic acid (bengalensisteroic acid ester) (2) together with the known compounds heneicosanyl cis-octadec-9-enoate (heneicosanyl oleate) (3), urs-12-en-3b-yl acetate (a-amyrin acetate) (4), and lup-20(29)-en-3b-ol (lupeol) (5). The structures of these phytoconstituents have been established on the basis of spectral data analysis, chemical reactions and comparison of literature. ª 2012 Production and hosting by Elsevier B.V. on behalf of King Saud University.
ChemInform Abstract: Flavones and Triterpenes from the Leaves of Vitex peduncularis
ChemInform, 2015
A new flavone, 4'-acetoxy-5-hydroxy-6,7-dimethoxyflavone 1 together with four known compounds, cirsimaritin 2, genkwanin 3, 3α-friedelinol 4 and 3β-friedelinol 5 have been isolated from the leaves of Vitex peduncularis Wall. (Verbenaceae). The structure of the new flavone was elucidated by detailed spectral (including 2D-NMR) and chemical studies.
Phytochemical Analysis, 2005
Twelve flavonoids, including seven flavones, four flavonols and one flavanone, were isolated from methanolic extract of the herbal drug 'Crataegi folium cum flore' (hawthorn leaves and flowers) by a combination of CC (over Amberlite XAD-7 and Sephadex LH-20) and preparative HPLC. Their structures, including that of the novel flavonol 8-methoxykaempferol 3-O-(6″ ″ ″ ″ ″-malonyl-β β β β β-glucopyranoside), were elucidated by homoand heteronuclear NMR and electrospray/MS. The 1 H-and 13 C-NMR of all compounds, including rotameric pairs of five flavone C-glycosides, were assigned. The presence and relative proportion of each rotamer was shown by various NMR experiments, including two-dimensional nuclear Overhauser and exchange spectroscopy, to depend on solvent, linkage position and structure of the C-glycosyl substituent.
Introduction and Interpretation of Flavonoids
Advanced Science, Engineering and Medicine Vol. 6, 1–16, 2014, 2014
An introduction to flavone, c-glucosyl flavones, flavone glycosides, acylated flavone glucosides, prenylated flavones, flavonoid sulfates, flavonoid glucuronides, a methylene dioxy flavonol, dihydroflavonols, acyl glucosylated flavonols, flavonol glycosides, flavanones, c-methylflavonoids, isoflavone, isoflavone glycosides, homoisolfavonoids, diprenyl isoflavones, isoflavanones, biflavones, biflavanone, chalcone, bicholcone, dihydrochalcone, enolchalcone, pyrano chalcones, oleanane triterpenoids and triterpene saponins. Their spectroscopic techniques, UV, IR, 1H-NMR, 13C-NMR and mass spectroscopy have been used in the identification and structure elucidation of the products isolated from different plants.
C-p-hydroxybenzoylglycoflavones from Citrullus colocynthis
Phytochemistry, 1997
In a flavonoid investigation of the fruits and aerial parts of Citrullus colocynthis six flavone C-glycosides were identified. The fruits contained isovitexin, iso-orientin and iso-orientin 3'-methyl ether, while the aerial parts contained three new C-p-hydroxybenzyl derivatives, viz. 8-C-p-hydroxybenzoylisovitexin, 6-C-phydroxybenzoylvitexin, and 8-C-p-hydroxybenzoylisovitexin 4'-O-glucoside. Their chemical identity was estabfished by NMR spectroscopic methods including 2D-NMR, as well as UV and MS analyses.
International Journal of Pharmacy and Pharmaceutical Sciences
Objective: The current investigation involves the isolation, characterization and prediction of biological activity spectra of the phytoconstituents from the ethanolic extract of the heartwood of Pterocarpus marsupium roxb. (Fabaceae). Methods: The heartwood (3 kg) was extracted in alcohol by cold maceration for 21 d and the compounds were isolated by column chromatography. The compounds thus isolated were characterised and their structures were elucidated by using assorted spectral data analysis, i.e., infrared radiation spectroscopy (IR), proton nuclear magnetic resonance (1 HNMR), carbon thirteen nuclear magnetic resonance (13 Results: Phytochemical investigation of ethanolic extract of the heartwood of Pterocarpus marsupium led to isolate two fatty esters and a phenolic compound characterised as n-octanyl n-octadeca-9,12-dienoate (n-octanyl linoleiate, 1), n-dodecanyl n-octadeca-9,12-dienoate (n-dodecanyl linoleiate, 2) and 2, 3-dioxymethylene phenol (3). These phytoconstituents are reported for first time in the heartwood of Pterocarpus marsupium Roxb. The in silico profiling of these phytoconstituents exhibited their broad spectra of biological activity. Compounds (1) and (2) showed their maximum activity as All-trans-retinyl-palmitate hydrolase inhibitor, anti eczematic, lipid metabolism regulator, etc. and compound (3) was found to be active as membrane integrity agonist, aspulvinone dimethylallyl transferases inhibitor, carminative, neurotransmitter uptake inhibitor, etc. C NMR) and direct analysis in real time mass spectrometry (DART-MS). PASS (prediction of activity spectra for substances) computer program was used to predict the biological activity spectra of the isolated compounds. Conclusion: These isolated phytoconstituents can be used as the marker compounds to establish the identity, quality and purity of the drug. The results of PASS prediction shall be very useful for establishing these phytoconstituents as active pharmacological moieties.
Isolation and identification of a flavone (quercetin) from Butea frondosa bark
Pharmaceutical Chemistry Journal, 2007
A flavone was isolated from the stem bark of Butea frondosa (Leguminosae). It was given a working name of BF-1 and characterized by m.p., 309 -311°C and an empirical formula of C 15 H 10 O 7 . On the basis of chemical and spectral evidence and upon comparison with the literature data, the isolated compound is identified for the first time as quercetin.