Phosphorylation of Human m1 Muscarinic Acetylcholine Receptors by G Protein-coupled Receptor Kinase 2 and Protein Kinase C (original) (raw)

Sequestration of muscarinic acetylcholine receptor m2 subtypes. Facilitation by G protein-coupled receptor kinase (GRK2) and attenuation by a dominant-negative mutant of GRK2

T. Haga

The Journal of biological chemistry, 1994

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Phosphorylation of muscarinic receptors: regulation by G proteins

T. Haga

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Phosphorylation by Protein Kinase C of the Muscarinic Acetylcholine Receptor

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Internalization and Down-regulation of Human Muscarinic Acetylcholine Receptor m2 Subtypes. ROLE OF THIRD INTRACELLULAR m2 LOOP AND G PROTEIN-COUPLED RECEPTOR KINASE 2

J. Lameh, T. Haga

Journal of Biological Chemistry, 1998

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Location of agonist-dependent-phosphorylation sites in the third intracellular loop of muscarinic acetylcholine receptors (m2 subtype)

T. Haga

European Journal of Biochemistry, 1994

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Activation of a GTP-Binding Protein and a GTP-Binding-Protein-Coupled Receptor Kinase (beta-Adrenergic-Receptor Kinase-1) by a Muscarinic Receptor m2 Mutant Lacking Phosphorylation Sites

T. Haga

European Journal of Biochemistry, 1994

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Desensitization and Internalization of the m2 Muscarinic Acetylcholine Receptor Are Directed by Independent Mechanisms

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Journal of Biological Chemistry, 1995

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Activation by G protein βγ subunits of β-adrenergic and muscarinic receptor kinase

T. Haga

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Dual regulation by G proteins of agonist-dependent phosphorylation of muscarinic acetylcholine receptors

T. Haga

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Mechanism of inhibition of TREK-2 (K2P10.1) by the Gq-coupled M3 muscarinic receptor

Dawon Kang

American Journal of Physiology-Cell Physiology, 2006

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Muscarinic Supersensitivity and Impaired Receptor Desensitization in G Protein–Coupled Receptor Kinase 5–Deficient Mice

Richard T Premont

Neuron, 1999

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A heterotrimeric G protein complex couples the muscarinic m1 receptor to phospholipase C-beta

Burghardt Wittig

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Relationship between agonist binding, phosphorylation and immunoprecipitation of the m3-muscarinic receptor, and second messenger responses

Gary Willars

British Journal of Pharmacology, 1995

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Differential agonist-induced regulation of human M2 and M3 muscarinic receptors

Martin Michel

Biochemical Pharmacology, 2003

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M3 Muscarinic Acetylcholine Receptor-Mediated Signaling Is Regulated by Distinct Mechanisms

Jeffrey Benovic

Molecular Pharmacology, 2008

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Regulation of Muscarinic Acetylcholine Receptor Expression and Functiona

Jacques Migeon

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Synergistic activation of a G protein-coupled receptor kinase by G protein beta gamma subunits and mastoparan or related peptides

T. Haga

The Journal of biological chemistry, 1994

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Molecular events associated with the regulation of signaling by M2 muscarinic receptors

Jeffrey Benovic

Life Sciences, 1999

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Coupling of M2 Muscarinic Receptors to Membrane Ion Channels via Phosphoinositide 3-Kinase γ and Atypical Protein Kinase C

Prasad Dhulipala

Journal of Biological Chemistry, 1999

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Classical and atypical agonists activate M1 muscarinic acetylcholine receptors through common mechanisms

Vladimír Doležal

Pharmacological research : the official journal of the Italian Pharmacological Society, 2015

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Regulation of muscarinic acetylcholine receptor signaling

Bin Li

Pharmacology & Therapeutics, 2003

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Estimation of Agonist Activity at G Protein-Coupled Receptors: Analysis of M2 Muscarinic Receptor Signaling through Gi/o,Gs, and G15

Frederick Ehlert

Journal of Pharmacology and Experimental Therapeutics, 2007

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Different sensitivities to agonist of muscarinic acetylcholine receptor subtypes

Tai Kubo

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Selectivity of Agonists for the Active State of M1 to M4 Muscarinic Receptor Subtypes

Frederick Ehlert

Journal of Pharmacology and Experimental Therapeutics, 2008

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Regulation of Membrane Targeting of the G Protein-coupled Receptor Kinase 2 by Protein Kinase A and Its Anchoring Protein AKAP79

Mei Cong

Journal of Biological Chemistry, 2001

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Agonist-induced desensitization and phosphorylation of m1-muscarinic receptors

Canan Nebigil

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Internalization of the m2 Muscarinic Acetylcholine Receptor

Vsevolod Gurevich

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GRKs as Modulators of Neurotransmitter Receptors

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Immunochemical Studies of the Muscarinic Acetylcholine Receptor

Stefano Marullo

Journal of Receptors and Signal Transduction, 1987

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G Protein-coupled Receptor Kinase GRK2 Is a Phospholipid-dependent Enzyme That Can Be Conditionally Activated by G Protein beta gamma Subunits

Jeffrey Benovic

Journal of Biological Chemistry, 1996

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The human muscarinic M1 acetylcholine receptor, when expressed in CHO cells, activates and downregulates both Gqα and G11α equally and non-selectively

Ian Mullaney

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Activation by G protein subunits of agonist-or light-dependent phosphorylation by muscarinic acetylcholine receptors and rhodopsin

T. Haga

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Characterization of M 2 muscarinic receptor activation of different G protein subtypes

Karl Åkerman

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Location in Muscarinic Acetylcholine Receptors of Sites for [ 3 H]Propylbenzilcholine Mustard Binding and for Phosphorylation with Protein Kinase C

T. Haga

Journal of Neurochemistry, 1990

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Discrete activation of transduction pathways associated with acetylcholine m1 receptor by several muscarinic ligands

Abraham Fisher

European Journal of Pharmacology: Molecular Pharmacology, 1994

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