Activation of a GTP-Binding Protein and a GTP-Binding-Protein-Coupled Receptor Kinase (beta-Adrenergic-Receptor Kinase-1) by a Muscarinic Receptor m2 Mutant Lacking Phosphorylation Sites (original ) (raw )Activation by G protein βγ subunits of β-adrenergic and muscarinic receptor kinase
T. Haga
Journal of Biological Chemistry
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Sequestration of muscarinic acetylcholine receptor m2 subtypes. Facilitation by G protein-coupled receptor kinase (GRK2) and attenuation by a dominant-negative mutant of GRK2
T. Haga
The Journal of biological chemistry, 1994
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Phosphorylation of Human m1 Muscarinic Acetylcholine Receptors by G Protein-coupled Receptor Kinase 2 and Protein Kinase C
T. Haga
Journal of Biological Chemistry, 1996
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Location of agonist-dependent-phosphorylation sites in the third intracellular loop of muscarinic acetylcholine receptors (m2 subtype)
T. Haga
European Journal of Biochemistry, 1994
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Phosphorylation of muscarinic receptors: regulation by G proteins
T. Haga
Life Sciences, 1993
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Dual regulation by G proteins of agonist-dependent phosphorylation of muscarinic acetylcholine receptors
T. Haga
FEBS Letters, 1990
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Haga, K., Haga, T. & Ichiyama, A. Reconstitution of the muscarinic acetylcholine receptor. Guanine nucleotide-sensitive high affinity binding of agonists to purified muscarinic receptors reconstituted with GTP-binding proteins (Gi and Go). J. Biol. Chem. 261, 10133-10140
T. Haga
Journal of Biological Chemistry
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Internalization and Down-regulation of Human Muscarinic Acetylcholine Receptor m2 Subtypes. ROLE OF THIRD INTRACELLULAR m2 LOOP AND G PROTEIN-COUPLED RECEPTOR KINASE 2
J. Lameh , T. Haga
Journal of Biological Chemistry, 1998
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Functional interaction of purified muscarinic receptors with purified inhibitory guanine nucleotide regulatory proteins reconstituted in phospholipid vesicles
T. Haga
The Journal of biological chemistry, 1986
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The regulation of cardiac α1-adrenergic receptors by guanine nucleotides and by muscarinic cholinergic agonists
William Roeske
European Journal of Pharmacology, 1980
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Phosphorylation by Protein Kinase C of the Muscarinic Acetylcholine Receptor
T. Haga
Journal of Neurochemistry, 1990
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Palmitoylation of Muscarinic Acetylcholine Receptor m2 Subtypes: Reduction in Their Ability to Activate G Proteins by Mutation of a Putative Palmitoylation Site, Cysteine 457, in the Carboxyl-Terminal Tail
T. Haga
Archives of Biochemistry and Biophysics, 1997
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Cardiac M2 receptors consist of two different types, both regulated by GTP
Atsushi Mizushima
European Journal of Pharmacology, 1987
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Interaction of muscarinic acetylcholine receptors and three kinds of GTP-binding proteins (Gi, Go and Gn) purified from porcine cerebrum and atrium
Gabriel Berstein
Neuroscience Research Supplements, 1988
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Coexpression studies with mutant muscarinic/adrenergic receptors provide evidence for intermolecular "cross-talk" between G-protein-linked receptors
Zvi Vogel
Proceedings of the National Academy of Sciences, 1993
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Characterization of M 2 muscarinic receptor activation of different G protein subtypes
Karl Åkerman
Neurochemistry International, 2004
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Role of βγ Subunits of G Proteins in Targeting the β-Adrenergic Receptor Kinase to Membrane-Bound Receptors
Joyce Easter
Science, 1992
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Activation and allosteric modulation of a muscarinic acetylcholine receptor
Peter Gmeiner
Nature, 2013
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Regulation of muscarinic receptor binding by guanine nucleotides and N-ethylmaleimide
Frederick Ehlert
Journal of supramolecular structure, 1980
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Differential Modification of the Interaction of Cardiac Muscarinic Cholinergic and β-Adrenergic Receptors with a Guanine Nucleotide Binding Component(s).
McHardy Smith
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Agonist binding to M1 muscarinic receptors is sensitive to guanine nucleotides
nick palermo
European Journal of Pharmacology: Molecular Pharmacology, 1989
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Muscarinic Supersensitivity and Impaired Receptor Desensitization in G Protein–Coupled Receptor Kinase 5–Deficient Mice
Richard T Premont
Neuron, 1999
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G-protein mediates voltage regulation of agonist binding to muscarinic receptors: effects on receptor-sodium channel interaction
Malka Cohen-Armon
Biochemistry, 1988
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GTP-binding proteins mediate the M2-muscarinic effect on the action potential in isolated sympathetic neurons of rabbits
Sumiko Mochida
Neuroscience Letters, 1988
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Differential agonist-induced regulation of human M2 and M3 muscarinic receptors
Martin Michel
Biochemical Pharmacology, 2003
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Distinct sequence elements control the specificity of G protein activation by muscarinic acetylcholine receptor subtypes
D Clapham
The EMBO Journal, 1990
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Regulation of Muscarinic Acetylcholine Receptor Expression and Functiona
Jacques Migeon
Annals of the New York Academy of Sciences, 1995
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The substance P receptor, which couples to Gq/11, is a substrate of beta-adrenergic receptor kinase 1 and 2
Jeffrey Benovic
The Journal of biological chemistry, 1993
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Desensitization and Internalization of the m2 Muscarinic Acetylcholine Receptor Are Directed by Independent Mechanisms
Paula Witt-enderby
Journal of Biological Chemistry, 1995
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Binding characteristics and functional G protein coupling of muscarinic acetylcholine receptors in rat duodenum smooth muscle membranes
Martin Schnittler
Naunyn-Schmiedeberg's Archives of Pharmacology, 1992
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Phosphorylation of chick heart muscarinic cholinergic receptors by the .beta.-adrenergic receptor kinase
Jeffrey Benovic
Biochemistry, 1989
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Immunochemical Studies of the Muscarinic Acetylcholine Receptor
Stefano Marullo
Journal of Receptors and Signal Transduction, 1987
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Modulation of the M2 Muscarinic Acetylcholine Receptor Activity with Monoclonal Anti-M2 Receptor Antibody Fragments
Gerd Wallukat
Journal of Biological Chemistry, 2004
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Cardiac muscarinic receptor binding is regulated by Na+ and guanine nucleotides
William Roeske
Journal of Biological Chemistry
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A heterotrimeric G protein complex couples the muscarinic m1 receptor to phospholipase C-beta
Burghardt Wittig
Proceedings of the National Academy of Sciences, 1996
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