Acid exposure impairs mucus secretion and disrupts mucus transport in neonatal piglet airways (original) (raw)

Acid exposure disrupts mucus secretion and impairs mucociliary transport in neonatal piglet airways

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American Journal of Physiology-Lung Cellular and Molecular Physiology, 2020

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Cystic fibrosis. Impaired mucus detachment disrupts mucociliary transport in a piglet model of cystic fibrosis

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Submucosal gland secretions in airways from cystic fibrosis patients have normal [Na+] and pH but elevated viscosity

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Loss of Anion Transport without Increased Sodium Absorption Characterizes Newborn Porcine Cystic Fibrosis Airway Epithelia

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Cystic Fibrosis Transmembrane Conductance Regulator Is Expressed in Mucin Granules from Calu-3 and Primary Human Airway Epithelial Cells

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MUC5AC and MUC5B Mucins Increase in Cystic Fibrosis Airway Secretions during Pulmonary Exacerbation

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Alexander Makhov

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MUC5AC and MUC5B Mucins Are Decreased in Cystic Fibrosis Airway Secretions

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Cystic fibrosis gene mutation reduces epithelial cell acidification and injury in acid-perfused mouse duodenum

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Mucus secretion by single tracheal submucosal glands from normal and cystic fibrosis transmembrane conductance regulator knockout mice

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Airway submucosal glands from cystic fibrosis swine suffer from abnormal ion transport across the serous acini, collecting duct, and ciliated duct

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Airway surface liquid pH is not acidic in children with cystic fibrosis

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Mucin Release from Rabbit Tracheal Epithelium in Response to Sera from Normal and Cystic Fibrosis Subjects

Pi-wan Cheng

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Mucous solids and liquid secretion by airways: studies with normal pig, cystic fibrosis human, and non-cystic fibrosis human bronchi

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Cystic fibrosis airway secretions exhibit mucin hyperconcentration and increased osmotic pressure

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Evidence for Periciliary Liquid Layer Depletion, Not Abnormal Ion Composition, in the Pathogenesis of Cystic Fibrosis Airways Disease

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Acta Paediatrica, 1989

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Mucin glycosylation changes in cystic fibrosis lung disease are not manifest in submucosal gland secretions

Nicolle Packer

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Malcolm King

Pediatric Research, 1981

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Faculty Opinions recommendation of Loss of anion transport without increased sodium absorption characterizes newborn porcine cystic fibrosis airway epithelia

Richard Naftalin

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MUCLIN expression in the cystic fibrosis transmembrane conductance regulator knockout mouse

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