Securinine alkaloids: A new class of GABA receptor antagonist (original) (raw)

Inhibition of [3H]GABA binding to rat brain synaptic membranes by bicuculline related alkaloids

Julianna Kardos

Biochemical Pharmacology, 1984

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(+)-Hydrastine, a potent competitive antagonist at mammalian GABAA receptors

Graham Johnston

British Journal of Pharmacology, 1990

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Bicuculline, an antagonist of GABA and synaptic inhibition in the spinal cord of the cat

Graham Johnston

Brain Research, 1971

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Bicuculline and gabazine are allosteric inhibitors of channel opening of the GABAA receptor

Joe Steinbach

The Journal of neuroscience : the official journal of the Society for Neuroscience, 1997

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Gaba agonists and antagonists

Graham Johnston

Biochemical Pharmacology, 1979

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Role of cholinergic mechanisms in the mechanism of action of bicuculline

Rita Ostrovskaya

Bulletin of Experimental Biology and Medicine, 1978

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Excitatory amino acid antagonists protect mice against seizures induced by bicuculline

W. Turski

Brain Research, 1990

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Chemical instability of the GABA antagonist bicuculline under physiological conditions

Graham Johnston

Brain Research, 1975

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GABA and bicuculline actions on mouse spinal cord and cortical neurons in cell culture

Linda Nowak

Brain Research, 1982

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Paradoxical anticonvulsant acitivity of the ?hyphen;Aminobutyrate antagonist bicuculline methiodide in the rat striatum

Esper Cavalheiro

Synapse, 1991

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An arylaminopyridazine derivative of gamma-aminobutyric acid (GABA) is a selective and competitive antagonist at the GABAA receptor site

Remy Schlichter

Proceedings of the National Academy of Sciences of the United States of America, 1985

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Action of N-methyl-bicuculline on the binding of γ-aminobutyric acid to a synaptosomal fraction of rat cerebral cortex

Paul Madtes

Experimental Neurology, 1975

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Antagonism between bicuculline and GABA in the cat brain

Graham Johnston

Brain Research, 1971

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5-[1‘-(2‘-N-Arylsulfonyl-1‘,2‘,3‘,4‘-tetrahydroisoquinolyl)]-4,5-dihydro-2(3H)-furanones: Positive Allosteric Modulators of the GABAA Receptor with a New Mode of Action

Rodolphe Razet

Journal of Medicinal Chemistry, 2000

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Bicuculline-insensitive gaba receptors on peripheral autonomic nerve terminals

N. Bowery

European Journal of Pharmacology, 1981

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Bicuculline actions on isolated rat atria, mouse vas-deferens and guinea-pig ileum are unrelated to GABA A receptor blockade

Riccardo Patacchini

General Pharmacology: The Vascular System, 1990

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Neurochemicals for the Investigation of GABAC Receptors

Graham Johnston

Neurochemical Research, 2010

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The epileptogenic action of the taurine analogue guanidinoethane sulfonate may be caused by a blockade of GABA receptors

JM Solis

Journal of Neuroscience Research, 1990

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Studies on the neuropharmacological activity of bicuculline and related compounds

Thomas Miller

Brain Research, 1976

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Antagonists of Ionotropic Receptors for the Inhibitory Neurotransmitter GABA: Therapeutic Indications

Tina Hinton

InTech eBooks, 2018

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Bicuculline-insensitive GABA receptors: studies on the binding of (-)-baclofen to rat cerebellar membranes

Graham Johnston

Neuroscience letters, 1984

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Quantitative evaluation of the potencies of GABA-receptor agonists and antagonists using the rat hippocampal slice preparation

John Kemp

British Journal of Pharmacology, 1986

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N,N′-Dicyclohexylsulfamide and N,N′-diphenethylsulfamide are anticonvulsant sulfamides with affinity for the benzodiazepine binding site of the GABAA receptor and anxiolytic activity in mice

Cristina Wasowski, Valentina Pastore, Luis Bruno-blanch, Andrea Enrique

Biochemical Pharmacology, 2012

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Direct Activation of GABAA Receptors by Loreclezole, an Anticonvulsant Drug with Selectivity for the β-Subunit

Giovanni Biggio

Neuropharmacology, 1996

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Synthesis, Structure−Activity Relationships at the GABA A Receptor in Rat Brain, and Differential Electrophysiological Profile at the Recombinant Human GABA A Receptor of a Series of Substituted 1,2-Diphenylimidazoles

Giovanni Biggio

Journal of Medicinal Chemistry, 2005

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Displacement of [3H]GABA binding to bovine brain receptors by sulfur-containing analogues

Mario Fontana

Neurochemistry International, 1990

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Kinetic differences in GABA receptor binding following GABA and bicuculline methiodide pretreatment

Gabor Maksay

Neuroscience Letters, 1984

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Inhibition of γ-aminobutyric acid uptake by bicuculline analogues

J. Kardos

European journal of …

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A Behavioural and Neurochemical Study in Rats of the Pharmacology of Loreclezole, a Novel Allosteric Modulator of the GABA A Receptor

Mike Snape

Neuropharmacology, 1996

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