The chicken left right organizer has nonmotile cilia which are lost in a stage-dependent manner in the talpid 3 ciliopathy (original) (raw)

TheTalpid3gene (KIAA0586) encodes a centrosomal protein that is essential for primary cilia formation

Alan Prescott

Development, 2009

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The Talpid3 gene (KIAA0586) encodes a centrosomal protein that is essential for primary cilia formation

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The mouse homeobox gene Noto regulates node morphogenesis, notochordal ciliogenesis, and left right patterning

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Proceedings of the National Academy of Sciences, 2007

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Loss of cilia causes embryonic lung hypoplasia, liver fibrosis, and cholestasis in the talpid3 ciliopathy mutant

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Proceedings of The Japan Academy Series B-physical and Biological Sciences, 2009

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Philip Beales

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Targeted mutation of the talpid3 gene in zebrafish reveals its conserved requirement for ciliogenesis and Hedgehog signalling across the vertebrates

Philip W Ingham

Development, 2011

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Vertebrate primary cilia: a sensory part of centrosomal complex in tissue cells, but a “sleeping beauty” in cultured cells?

Irina Alieva

Cell Biology International, 2004

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Developmental Dynamics, 2008

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Fish and frogs: models for vertebrate cilia signaling

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Cilia-Driven Leftward Flow Determines Laterality in Xenopus

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The stumpy gene is required for mammalian ciliogenesis

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Proceedings of the National Academy of Sciences of the United States of America, 2008

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Biophysical Journal, 2005

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RFX3 governs growth and beating efficiency of motile cilia in mouse and controls the expression of genes involved in human ciliopathies

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RFX2 is essential in the ciliated organ of asymmetry and an RFX2 transgene identifies a population of ciliated cells sufficient for fluid flow

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Vertebrate Smoothened functions at the primary cilium

Kevin Corbit, Veena Singla, Andrew Norman, Jeremy Reiter

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The Transcription Factor RFX3 Directs Nodal Cilium Development and Left-Right Asymmetry Specification

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Molecular and Cellular Biology, 2004

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Chibby functions in Xenopus ciliary assembly, embryonic development, and the regulation of gene expression

Michael Klymkowsky

Developmental Biology, 2014

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