Inter-strand crosslinking of DNA by nitrogen mustard (original) (raw)

A combined experimental and computational study on the interaction of nitrogen mustards with DNA

Med. Chem. Commun., 2016

Differences between melphalan and nitrogen mustard in the formation and removal of DNA cross-links

Cancer research, 1978

Characterization of DNA-protein crosslinks formed by treatment of L1210 cells and nuclei with bis(2-chloroethyl)methylamine (nitrogen mustard)

kurt kohn

Biochemistry, 1978

View PDFchevron_right

A Bridging Water Anchors the Tethered 5-(3-Aminopropyl)-2′-deoxyuridine Amine in the DNA Major Groove Proximate to the N+2 C·G Base Pair: Implications for Formation of Interstrand 5′-GNC-3′ Cross-Links by Nitrogen Mustards † , ‡

Manjori Ganguly, Luis A Marky

Biochemistry, 2008

View PDFchevron_right

Cross-Linking of the DNA Repair Protein O6-Alkylguanine DNA Alkyltransferase to DNA in the Presence of Antitumor Nitrogen Mustards

Natalia Tretyakova

Chemical Research in Toxicology, 2008

View PDFchevron_right

DNA damage and repair in mouse leukemia L1210 cells treated with nitrogen mustard, 1,3-bis(2-chloroethyl)-1-nitrosourea, and other nitrosoureas

kurt kohn

Cancer research, 1977

View PDFchevron_right

Synthesis and Molecular Modeling of a Nitrogen Mustard DNA Interstrand Crosslink

Todor Angelov

Chemistry - A European Journal, 2010

View PDFchevron_right

Cross-linking and repair of DNA in sensitive and resistant strains of E. coli treated with nitrogen mustard

kurt kohn

Proceedings of the National Academy of Sciences, 1965

View PDFchevron_right

Interstrand cross-linking of DNA by 1,3-bis(2-chloroethyl)-1-nitrosourea and other 1-(2-haloethyl)-1-nitrosoureas

kurt kohn

Cancer research, 1977

View PDFchevron_right

Gene-specific DNA Interstrand Cross-Links Produced by Nitrogen Mustard in the Human Tumor Cell Line CoIo32OHSR

Bernard Futscher

View PDFchevron_right

Synthesis and DNA-sequence selectivity of a series of mono- and difunctional 9-aminoacridine nitrogen mustards

kurt kohn

Journal of Medicinal Chemistry, 1994

View PDFchevron_right

Nitrogen mustard- and half-mustard-induced damage in Escherichia coli requires different DNA repair pathways

Claudia LAGE

Mutation Research/Genetic Toxicology and Environmental Mutagenesis, 2005

View PDFchevron_right

A structural basis for a phosphoramide mustard-induced DNA interstrand cross-link at 5'-d (GAC)

Daniel Barsky

Proceedings of the National Academy of Sciences

View PDFchevron_right

High-performance liquid chromatographic determination of N-[2-(hydroxyethyl)-N-(2-(7-guaninyl)ethyl)]methylamine, a reaction product between nitrogen mustard and DNA and its application to biological samples

Melinda Chandler

Journal of chromatography. B, Biomedical sciences and applications, 1998

View PDFchevron_right

Sensitivity to Nitrogen Mustard Relates to the Ability of Processing DNA Damage in Chinese Hamster Ovary Cells

Peter R Møller

Pharmacology & Toxicology, 2008

View PDFchevron_right

Covalent DNA–Protein Cross-Linking by Phosphoramide Mustard and Nornitrogen Mustard in Human Cells

Natalia Tretyakova

Chemical Research in Toxicology, 2016

View PDFchevron_right

DNA damage and mutagenesis induced by nitrogen mustards

David Shuker

Mutation Research/Reviews in Genetic Toxicology, 1994

View PDFchevron_right

Properties of DNA modified with N-methyl-N-nitrosourea

E. Lukášová

Radiation and Environmental Biophysics, 1977

View PDFchevron_right

Effects of disintegration of incorporated 3H and 32P on the physical and biological properties of DNA

Maurice Fox

Journal of Molecular Biology, 1970

View PDFchevron_right

Inter strand crosslinks in DNA induced in vivo by percutaneous application of sulphur mustard to rats and mice

Vit Rehacek

Mutation Research/Genetic Toxicology and Environmental Mutagenesis, 2018

View PDFchevron_right

Formation of different reaction products with single- and double-stranded DNA by the ortho-quinone and the semi-quinone free radical of etoposide (VP-16-213)

D. Mans

Biochemical Pharmacology, 1991

View PDFchevron_right

Dna-protein cross-linking and dna interstrand cross-linking by haloethylnitrosoureas in l1210 cells

kurt kohn

Cancer Research, 1978

View PDFchevron_right

Formation of interstrand cross-links in chloroacetaldehyde-treated DNA demonstrated by ethidium bromide fluorescence

Sylvia Spengler

Cancer research, 1988

View PDFchevron_right

Alkylated DNA: Buoyant density changes and modes of decomposition

K. Kohn

Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 1967

View PDFchevron_right

Generation of DNA Interstrand Cross-Links by Post-Synthetic Reductive Amination

Todor Anguelov

Organic Letters, 2009

View PDFchevron_right

Influence of WR2721 on DNA cross-linking by nitrogen mustard in normal mouse bone marrow and leukemia cells in vivo

Fred Valeriote

Cancer research, 1988

View PDFchevron_right

The production of strand breaks in dna in the presence of the hydroxylamine of sr-2508 (1-[N-(2-hydroxyethyl)acetamido]2-nitroimidazole) at neutral pH

Keith Laderoute

International Journal of Radiation Oncology*Biology*Physics, 1986

View PDFchevron_right

DNA sequence selectivity of guanine–N7 alkylation by nitrogen mustards

Neil Gibson

Nucleic Acids Research, 1986

View PDFchevron_right

Production of strand breaks in DNA in the presence of the hydroxylamine of SR-2508 (1-(N-(2-hydroxyethyl)acetamido)-2-nitroimidazole) at neutral pH

Keith Laderoute

Int J Radiat Oncol Biol Phys, 1986

View PDFchevron_right

Gene and human tumour cell line specific differencesin nitrogen mustard induced DNA alkylation and interstrand crosslinking frequencies

keith Grimaldi

Nucleic Acids Research, 1998

View PDFchevron_right

Heterogeneity of nitrogen mustard-induced DNA damage and repair at the level of the gene in Chinese hamster ovary cells

Karsten Wassermann

The Journal of biological chemistry, 1990

View PDFchevron_right

The intermediate in the photodegradation of DNA in the presence of acridine orange

Utpal Chaudhuri

Archives of Biochemistry and Biophysics, 1974

View PDFchevron_right

Interstrand DNA Cross-Links Derived from Reaction of a 2-Aminopurine Residue with an Abasic Site

Tuhin Haldar

ACS Chemical Biology, 2019

View PDFchevron_right

DNA-directed alkylating agents. 1. Structureactivity relationships for acridine-linked aniline mustards: consequences of varying the reactivity of the mustard

Lance Gravatt

Journal of Medicinal Chemistry, 1990

View PDFchevron_right

Alteration of the groove width of DNA induced by the multimodal hydrogen bonding of denaturants with DNA bases in its grooves affects their stability

Prashant Singh

Biochimica et Biophysica Acta (BBA) - General Subjects, 2020

View PDFchevron_right

Inter-strand crosslinking of DNA by nitrogen mustard (original) (raw)

Related papers