Differences between melphalan and nitrogen mustard in the formation and removal of DNA cross-links (original) (raw)

Formation and removal of DNA cross-links induced by melphalan and nitrogen mustard in relation to drug-induced cytotoxicity in human melanoma cells

R. Lewensohn

1987

View PDFchevron_right

DNA damage and repair in mouse leukemia L1210 cells treated with nitrogen mustard, 1,3-bis(2-chloroethyl)-1-nitrosourea, and other nitrosoureas

kurt kohn

Cancer research, 1977

View PDFchevron_right

Gene and human tumour cell line specific differencesin nitrogen mustard induced DNA alkylation and interstrand crosslinking frequencies

keith Grimaldi

Nucleic Acids Research, 1998

View PDFchevron_right

Influence of WR2721 on DNA cross-linking by nitrogen mustard in normal mouse bone marrow and leukemia cells in vivo

Fred Valeriote

Cancer research, 1988

View PDFchevron_right

DNA cross-linking as an indicator of sensitivity and resistance of mouse L1210 leukemia to cis-diamminedichloroplatinum(II) and L-phenylalanine mustard

kurt kohn

Cancer research, 1981

View PDFchevron_right

Gene-specific DNA Interstrand Cross-Links Produced by Nitrogen Mustard in the Human Tumor Cell Line CoIo32OHSR

Bernard Futscher

View PDFchevron_right

Relationship between DNA Cross-Links, Cell Cycle, and Apoptosis in Burkitt's Lymphoma Cell Lines Differing in Sensitivity to Nitrogen Mustard

Ian Magrath

1991

View PDFchevron_right

Induction of DNA breaks and apoptosis in crosslink-hypersensitive V79 cells by the cytostatic drug beta-D-glucosyl-ifosfamide mustard

Bernd Kaina

British journal of cancer, 2002

View PDFchevron_right

Dna-protein cross-linking and dna interstrand cross-linking by haloethylnitrosoureas in l1210 cells

kurt kohn

Cancer Research, 1978

View PDFchevron_right

DNA damage and mutagenesis induced by nitrogen mustards

David Shuker

Mutation Research/Reviews in Genetic Toxicology, 1994

View PDFchevron_right

Covalent DNA–Protein Cross-Linking by Phosphoramide Mustard and Nornitrogen Mustard in Human Cells

Natalia Tretyakova

Chemical Research in Toxicology, 2016

View PDFchevron_right

Defective DNA cross-link removal in Chinese hamster cell mutants hypersensitive to bifunctional alkylating agents

Larry Thompson

Cancer Research, 1985

View PDFchevron_right

Investigation of Resistance to DNA Cross-Linking Agents in 9L Cell Lines with Different Sensitivities to Chloroethylnitrosoureas

Massimo Gerosa

Cancer Research, 1985

View PDFchevron_right

Characterization of DNA-protein crosslinks formed by treatment of L1210 cells and nuclei with bis(2-chloroethyl)methylamine (nitrogen mustard)

kurt kohn

Biochemistry, 1978

View PDFchevron_right

DNA cross-linking by in vivo treatment with 1-(2-chloroethyl)-3-(4-methylcyclohexyl)-1-nitrosourea of sensitive and resistant human colon carcinoma xenograms in nude mice

kurt kohn

Cancer research, 1978

View PDFchevron_right

Induction of DNA breaks and apoptosis in crosslink-hypersensitive V79 cells by the cytostatic drug β-D-glucosyl-ifosfamide mustard

Bernd Kaina

British Journal of Cancer, 2002

View PDFchevron_right

Sensitivity to Nitrogen Mustard Relates to the Ability of Processing DNA Damage in Chinese Hamster Ovary Cells

Peter R Møller

Pharmacology & Toxicology, 2008

View PDFchevron_right

Inter strand crosslinks in DNA induced in vivo by percutaneous application of sulphur mustard to rats and mice

Vit Rehacek

Mutation Research/Genetic Toxicology and Environmental Mutagenesis, 2018

View PDFchevron_right

DNA crosslinking and cytotoxicity in normal and transformed human cells treated with antitumor nitrosoureas

kurt kohn

Proceedings of the National Academy of Sciences, 1980

View PDFchevron_right

Correlation between the cytotoxicity of melphalan and DNA crosslinks as detected by the ethidium bromide fluorescence assay in the F1 variant of B16 melanoma cells

STELLA OBANDO GARCIA

Biochemical Pharmacology, 1988

View PDFchevron_right

Strand breaks in DNA from normal and transformed human cells treated with 1,3-bis(2-chloroethyl)-1-nitrosourea

kurt kohn

Cancer research, 1977

View PDFchevron_right

Nitrogen mustard-DNA interaction in melphalan-resistant mammary carcinoma cells with elevated intracellular glutathione and glutathione-S-transferase activity

Robyn Schecter

Cancer Chemotherapy and Pharmacology, 1992

View PDFchevron_right

Inter-strand crosslinking of DNA by nitrogen mustard

kurt kohn

Journal of Molecular Biology, 1966

View PDFchevron_right

Studies on DNA repair in human lymphocytes treated with proximate carcinogens and alkylating agents

Stewart Sell

Cancer Research

View PDFchevron_right

High-Dose Selection with Mafosfamide Results in Sensitivity to DNA Cross-Linking Agents: Characterization of Hypersensitive Cell Lines

Bernd Kaina

Cancer Research, 1997

View PDFchevron_right

Kinetics of formation and disappearance of a DNA cross-linking effect in mouse leukemia L1210 cells treated with cis- and trans-diamminedichloroplatinum(II)

kurt kohn

Cancer research, 1978

View PDFchevron_right

Chemically induced DNA damage in isolated rabbit lung cells

Jørn Holme

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, 1993

View PDFchevron_right

DNA double-strand breaks in mammalian cells after exposure to intercalating agents

Matthews Bradley

Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 1981

View PDFchevron_right

Dose and interval relationship for the interaction of WR-2721 and nitrogen mustard with normal and malignant cells

Fred Valeriote

International Journal of Radiation Oncology*Biology*Physics, 1984

View PDFchevron_right

Biological and chemical effects of mustard gas in yeast

Axel Ruhland

Mutation Research-fundamental and Molecular Mechanisms of Mutagenesis, 1979

View PDFchevron_right