Stat1 combines signals derived from IFN-γ and LPS receptors during macrophage activation (original) (raw)
Protein inhibitor of activated signal transducer and activator of transcription (STAT)-1 (PIAS-1) regulates the IFN-γ response in macrophage cell lines
Eleonora Benedetti
Cellular Signalling, 2002
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Requirement for STAT1 in LPS‐induced gene expression in macrophages
Thomas Hamilton
Journal of Leukocyte Biology, 2001
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Differentiation-Regulated Serine Phosphorylation of STAT1 Promotes GAF Activation in Macrophages
Thomas Decker
Molecular and Cellular Biology, 1995
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Phosphorylation of the Stat1 Transactivation Domain Is Required for Full-Fledged IFN-γ-Dependent Innate Immunity
Thomas Kolbe
Immunity, 2003
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Impaired response to interferon-γin activated macrophages due to tyrosine nitration of STAT1 by endogenous nitric oxide
Jeremy Pearson
British Journal of Pharmacology, 2001
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Response to interferons and antibacterial innate immunity in the absence of tyrosine-phosphorylated STAT1
Thomas Decker
EMBO reports, 2016
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Modulation of Stat-1 in Human Macrophages Infected with Different Species of Intracellular Pathogenic Bacteria
Mauro Magnani
Journal of immunology research, 2016
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Toll-like Receptors 2 and 4 Activate STAT1 Serine Phosphorylation by Distinct Mechanisms in Macrophages
Stefanie Vogel
Journal of Biological Chemistry, 2003
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STAT3 tyrosine phosphorylation is critical for interleukin 1 beta and interleukin-6 production in response to lipopolysaccharide and live bacteria
Ruchi Rastogi, Lobelia Samavati
Molecular Immunology, 2009
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LPS Does Not Directly Induce STAT Activity in Mouse Macrophages
thomas hamilton
Cellular Immunology, 1996
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Autocrine/Paracrine IFN-ab Mediates the Lipopolysaccharide-Induced Activation of Transcription Factor Stat1a in Mouse Macrophages: Pivotal Role of Stat1a in Induction of the Inducible Nitric Oxide Synthase Gene1
Stefanie Vogel
2000
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The generation of macrophages with anti-inflammatory activity in the absence of STAT6 signaling
Prabha Chandrasekaran
Journal of leukocyte biology, 2015
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Interferons up-regulate STAT1, STAT2, and IRF family transcription factor gene expression in human peripheral blood mononuclear cells and macrophages
Ilkka Julkunen
Journal of Immunology, 1997
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TLR4, but not TLR2, mediates IFN-β–induced STAT1α/β-dependent gene expression in macrophages
thomas hamilton
Nature Immunology, 2002
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IFN consensus sequence binding protein potentiates STAT1-dependent activation of IFNgamma -responsive promoters in macrophages
Lucia Gabriele
Proceedings of the National Academy of Sciences, 2000
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Cytokine receptor signalling in neonatal macrophages: defective STAT-1 phosphorylation in response to stimulation with IFN- γ
Katalin Goda
Clinical & Experimental Immunology, 2001
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IFN- -Primed Macrophages Exhibit Increased CCR2-Dependent Migration and Altered IFN- Responses Mediated by Stat1
Hao Ho
The Journal of Immunology, 2005
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STAT1 Regulates Lipopolysaccharide- and TNF-α-Dependent Expression of Transporter Associated with Antigen Processing 1 and Low Molecular Mass Polypeptide 2 Genes in Macrophages by Distinct Mechanisms
Antonio Celada
The Journal of Immunology, 2004
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STAT1 Regulates Lipopolysaccharide- and TNF- -Dependent Expression of Transporter Associated with Antigen Processing 1 and Low Molecular Mass Polypeptide 2 Genes in Macrophages by Distinct Mechanisms
Marina Brucet
The Journal of Immunology, 2004
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Analysis of the IFN-γ-Signaling Pathway in Macrophages at Different Stages of Maturation1
Mary Ann McDowell
The Journal of Immunology, 1998
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Pathways Regulation by STAT1Dependent Pamidronate in Murine Macrophages: Expression by IFN{gamma} and Modulation of TNF{alpha} Gene
Sivadasan Kanangat
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Adenosine Blocks IFN-γ-Induced Phosphorylation of STAT1 on Serine 727 to Reduce Macrophage Activation
Rama Kota
The Journal of Immunology, 2009
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Colony-stimulating factor 1-induced STAT1 and STAT3 activation is accompanied by phosphorylation of Tyk2 in macrophages and Tyk2 and JAK1 in fibroblasts
Anthony Jaworowski
Blood, 1995
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Stat1 Negatively Regulates Immune-Mediated Injury with Anaplasma phagocytophilum Infection
John Dumler
The Journal of Immunology, 2014
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Sensitization of IFN-γ Jak-STAT signaling during macrophage activation
James Woods
Nature Immunology, 2002
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Autocrine/Paracrine IFN-αβ Mediates the Lipopolysaccharide-Induced Activation of Transcription Factor Stat1α in Mouse Macrophages: Pivotal Role of Stat1α in Induction of the Inducible Nitric Oxide Synthase Gene
Stefanie Vogel
The Journal of Immunology, 1998
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Stress-induced phosphorylation of STAT1 at Ser727 requires p38 mitogen-activated protein kinase whereas IFN-gamma uses a different signaling pathway
Thomas Decker
1999
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Differential Effects of CpG DNA on IFN- Induction and STAT1 Activation in Murine Macrophages versus Dendritic Cells: Alternatively Activated STAT1 Negatively Regulates TLR Signaling in Macrophages
Thomas Decker
The Journal of Immunology, 2007
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The activating effect of IFN-γ on monocytes/macrophages is regulated by the LIF–trophoblast–IL-10 axis via Stat1 inhibition and Stat3 activation
Cathy Vaillancourt
Cellular & Molecular Immunology, 2014
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Triggering of Toll-like receptors modulates IFN-γ signaling: involvement of serine 727 STAT1 phosphorylation and suppressors of cytokine signaling
Klaus Heeg
European Journal of Immunology, 2003
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Activity of Stat Family Transcription Factors is Developmentally Controlled in Cells of the Macrophage Lineage
Gaf Gaf
Immunobiology, 1995
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Differential effects of CpG DNA on IFN-β induction and STAT1 activation in murine macrophages versus dendritic cells: alternatively activated STAT1 negatively regulates TLR signaling in macrophages
Thomas Decker
2007
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Differential effects of CpG DNA on IFN-beta induction and STAT1 activation in murine macrophages versus dendritic cells: alternatively activated STAT1 negatively regulates TLR signaling in macrophages
Thomas Decker
Journal of Immunology, 2007
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