X-ray crystallographic study of DNA duplex cross-linking: simultaneous binding to two d (CGTACG) 2 molecules by a bis (9-aminoacridine-4-carboxamide) derivative (original ) (raw )A novel form of intercalation involving four DNA duplexes in an acridine-4-carboxamide complex of d(CGTACG)(2)
Laurence Wakelin
Nucleic acids research, 2000
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The interactions of monomeric acridines and unsymmetrical bisacridines (UAs) with DNA duplexes: an insight provided by NMR and MD studies
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Scientific Reports
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Major Groove Binding and ‘DNA-Induced' Fit in the Intercalation of a Derivative of the Mixed Topoisomerase I/II Poison N -(2-(Dimethylamino)ethyl)acridine-4- carboxamide (DACA) into DNA: X-ray Structure Complexed to d(CG(5-BrU)ACG) 2 at 1.3-Å Resolution
Alan Todd
Journal of Medicinal Chemistry, 1999
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A macrocyclic bis-acridine shifts the equilibrium from duplexes towards DNA hairpins
Jean Vigneron
Nucleic Acids Research, 1997
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Acridinecarboxamide topoisomerase poisons: structural and kinetic studies of the DNA complexes of 5-substituted 9-amino-(N-(2-dimethylamino)ethyl)acridine-4-carboxamides
Laurence Wakelin
Molecular pharmacology, 2000
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Interaction of an Acridine Dimer with DNA Quadruplex Structures
Jean Vigneron
Journal of Biomolecular Structure and Dynamics, 2001
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Unusual intercalation of acridin-9-ylthiourea into the 5'-GA/TC DNA base step from the minor groove: implications for the covalent DNA adduct profile of a novel platinum-intercalator conjugate
Hemanta Baruah
Nucleic Acids Research, 2003
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Bioorganic & Medicinal Chemistry Letters, 2007
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Antonino Corsaro
European Journal of Medicinal Chemistry, 2014
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Crystal Structure of the Topoisomerase II Poison 9-Amino-[ N -(2-dimethylamino)ethyl]acridine-4-carboxamide Bound to the DNA Hexanucleotide d(CGTACG) 2 †
Laurence Wakelin
Biochemistry, 1999
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Structural Characterisation of Bisintercalation in Higher-order DNA at a Junction-like Quadruplex
Alan Todd
Journal of Molecular Biology, 2002
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Kinetic and equilibrium binding studies of amsacrine-4-carboxamides: a class of asymmetrical DNA intercalating agents which bind by threading through the DNA helix
Laurence Wakelin
Journal of Medicinal Chemistry, 1990
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Christian BAILLY
Molecular cancer therapeutics, 2005
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Variable role of ions in two drug intercalation complexes of DNA
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JBIC Journal of Biological Inorganic Chemistry, 2005
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Modeling and Biological Investigations of an Unusual Behavior of Novel Synthesized Acridine-Based Polyamine Ligands in the Binding of Double Helix and G-Quadruplex DNA
Andrea Bencini
ChemMedChem, 2010
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Exploratory analysis of structural properties of DNA-intercalator complexes in crystalline state
Rudolf Kiralj
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A strong preference for the TA/TA dinucleotide step discovered for an acridine-based, potent antitumor dsDNA intercalator, C-1305: NMR-driven structural and sequence-specificity studies
Tomasz Laskowski
Scientific Reports
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ACMA (9-amino-6-chloro-2-methoxy acridine) forms three complexes in the presence of DNA
Fernando Secco , Natalia Busto
Physical Chemistry Chemical Physics, 2011
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Chemotherapeutic potential of 9-phenyl acridine: biophysical studies on its binding to DNA
Angshuman Bagchi
European Biophysics Journal With Biophysics Letters, 2010
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Interstrand DNA Cross-Links Derived from Reaction of a 2-Aminopurine Residue with an Abasic Site
Tuhin Haldar
ACS Chemical Biology, 2019
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Polyfunctional DNA intercalating agents
Laurence Wakelin
Medicinal Research Reviews, 1986
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Kinetic studies on the formation of acridine-linked DNA triple helices
Keith Fox
FEBS Letters, 1995
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The interaction of intercalators and groove-binding agents with DNA triple-helical structures: The influence of ligand structure, DNA backbone modifications and sequence
Shijie Yao
Journal of Molecular Recognition, 1994
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Monitoring the sequence specific intercalation in nucleic acids by 9-substituted acridine-4-carboxamides
Raghab Parajuli
Indian journal of chemistry. Sect. A: Inorganic, physical, theoretical & analytical, 2006
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Interactions of Acridine Antitumor Agents with DNA: Binding Energies and Groove Preferences
David Graves
Biochemistry, 1995
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DNA polyintercalating drugs: DNA binding of diacridine derivatives
Jacques Barbet
Proceedings of the National Academy of Sciences, 1975
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Bioorganic & Medicinal Chemistry, 2011
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