UVA photoactivation of DNA containing halogenated thiopyrimidines induces cytotoxic DNA lesions (original) (raw)
Identification of potentially cytotoxic lesions induced by UVA photoactivation of DNA 4-thiothymidine in human cells
Antony Young
Nucleic Acids Research, 2011
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4-thiothymidine sensitization of DNA to UVA offers potential for a novel photochemotherapy
Antony Young
Photochemical & Photobiological Sciences, 2012
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Multiple forms of DNA Damage Caused by UVA Photoactivation of DNA 6-Thioguanine
Reto Brem
Photochemistry and Photobiology, 2012
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Efficient DNA interstrand crosslinking by 6-thioguanine and UVA radiation
Ilse Daehn
DNA Repair, 2011
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Photoinduced Damage to Cellular DNA: Direct and Photosensitized Reactions†
Jean Cadet
Photochemistry and Photobiology, 2012
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Reactive oxygen species generated by thiopurine/UVA cause irreparable transcription-blocking DNA lesions
Reto Brem
Nucleic Acids Research, 2009
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Oxidatively-generated damage to DNA and proteins mediated by photosensitized UVA
Reto Brem
Free Radical Biology and Medicine
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UVA-induced cyclobutane pyrimidine dimers in DNA: a direct photochemical mechanism?
Szilvia KARPATI, Ákos Bányász
Organic & Biomolecular Chemistry, 2010
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Bipyrimidine Photoproducts Rather than Oxidative Lesions Are the Main Type of DNA Damage Involved in the Genotoxic Effect of Solar UVA Radiation †
Jean Cadet
Biochemistry, 2003
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Photoprotection of DNA (in vitro) by acyclothymidine dinucleosides
Abbas Raza
Bioorganic & Medicinal Chemistry Letters, 2013
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Repair of the three main types of bipyrimidine DNA photoproducts in human keratinocytes exposed to UVB and UVA radiations
Jean Cadet
DNA Repair, 2005
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DNA breakage and cell cycle checkpoint abrogation induced by a therapeutic thiopurine and UVA radiation
Reto Brem
Oncogene, 2010
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On the mechanism of photo-induced nucleic acid cleavage using N-aroyloxy-2-thiopyridones
Emmanuel Theodorakis
Tetrahedron Letters, 1998
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Protein Oxidation and DNA Repair Inhibition by 6-Thioguanine and UVA Radiation
Reto Brem
Journal of Investigative Dermatology, 2014
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Synthesis and DNA Photocleavage Activity of S-Alkylated 2-thiopyrimidines Current Trends in Biotechnology and Chemical Research
Ajay Sharma
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Deamination of Cytosine-containing Pyrimidine Photodimers in UV-irradiated DNA
Zvi Livneh
Journal of Biological Chemistry, 1995
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UVB and UVA radiation-mediated damage to isolated and cellular DNA
Jean Cadet
Pure and Applied Chemistry, 2000
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UVB and UVA induced formation of photoproducts within cellular DNA
Jean Cadet
From DNA Photolesions to Mutations, Skin Cancer and Cell Death, 2005
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Sensitized formation of oxidatively generated damage to cellular DNA by UVA radiation
Paolo Di Mascio
Photochemical & Photobiological Sciences, 2009
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Thiothymidine plus low-dose UVA kills hyperproliferative human skin cells independently of their human papilloma virus status
Andrew J Massey
Molecular Cancer Therapeutics, 2007
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Photolysis of N-Hydroxypyridinethiones: A New Source of Hydroxyl Radicals for the Direct Damage of Cell-Free and Cellular DNA
Bernd Epe
Nucleic Acids Research, 1996
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Novel cytotoxic DNA sequence and minor groove targeted photosensitizers: Conjugates of pyrene and netropsin analogues
Michael Wyatt
Bioorganic & Medicinal Chemistry, 1995
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Distribution of UV light-induced damage in a defined sequence of human DNA: detection of alkaline-sensitive lesions at pyrimidine nucleoside-cytidine sequences
Judith Lippke, Lynn Gordon
Proceedings of the National Academy of Sciences, 1981
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Cyclobutane Pyrimidine Dimers are the Main Mutagenic DNA Photoproducts in DNA Repair-deficient Trichothiodystrophy Cells
Alain Sarasin
Cancer Research, 1998
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Cyclobutane pyrimidine dimers are predominant DNA lesions in whole human skin exposed to UVA radiation
Jean Cadet
Proceedings of the National Academy of Sciences, 2006
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Probing photoprotection properties of lipophilic chain conjugated thiourea-aryl group molecules to attenuate ultraviolet-A induced cellular and DNA damages
Sobia Rana
Scientific Reports
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Molecular mechanisms of ultraviolet radiation-induced DNA damage and repair
Madhu Tyagi, Rajesh Rastogi
Journal of nucleic acids, 2010
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Phototoxic Potential of Different DNA Intercalators for Skin Cancer Therapy: In Vitro Screening
Paulo Ribeiro
International Journal of Molecular Sciences, 2023
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DNA repair inhibition by UVA photoactivated fluoroquinolones and vemurafenib
Reto Brem
Nucleic Acids Research, 2014
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Assessment of ultraviolet toxicity depending on DNA-damage using cyclobutane pyrimidine dimer formation in ultraviolet irradiated cells
Dr. Runa Masuma
2014
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Detection of the thietane precursor in the UVA formation of the DNA 6-4 photoadduct
Carlos E. Crespo-Hernández
Nature Communications, 2020
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Monomeric Base Damage Products from Guanine, Adenine, and Thymine Induced by Exposure of DNA to Ultraviolet Radiation
M. Dizdaroglu
Biochemistry, 1995
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Insight in DNA Repair of UV-induced Pyrimidine Dimers by Chromatographic Methods
Jean Cadet
Photochemistry and photobiology, 2017
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Modulation of exogenous and endogenous levels of thioredoxin in human skin fibroblasts prevents DNA damaging effect of ultraviolet A radiation
Christine Didier
Free Radical Biology and Medicine, 2001
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UV wavelength-dependent DNA damage and human non-melanoma and melanoma skin cancer
Gerd P Pfeifer
Photochemical & Photobiological Sciences, 2012
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