UVA photoactivation of DNA containing halogenated thiopyrimidines induces cytotoxic DNA lesions (original) (raw)

Identification of potentially cytotoxic lesions induced by UVA photoactivation of DNA 4-thiothymidine in human cells

Antony Young

Nucleic Acids Research, 2011

View PDFchevron_right

4-thiothymidine sensitization of DNA to UVA offers potential for a novel photochemotherapy

Antony Young

Photochemical & Photobiological Sciences, 2012

View PDFchevron_right

Multiple forms of DNA Damage Caused by UVA Photoactivation of DNA 6-Thioguanine

Reto Brem

Photochemistry and Photobiology, 2012

View PDFchevron_right

Efficient DNA interstrand crosslinking by 6-thioguanine and UVA radiation

Ilse Daehn

DNA Repair, 2011

View PDFchevron_right

Photoinduced Damage to Cellular DNA: Direct and Photosensitized Reactions†

Jean Cadet

Photochemistry and Photobiology, 2012

View PDFchevron_right

Reactive oxygen species generated by thiopurine/UVA cause irreparable transcription-blocking DNA lesions

Reto Brem

Nucleic Acids Research, 2009

View PDFchevron_right

Oxidatively-generated damage to DNA and proteins mediated by photosensitized UVA

Reto Brem

Free Radical Biology and Medicine

View PDFchevron_right

UVA-induced cyclobutane pyrimidine dimers in DNA: a direct photochemical mechanism?

Szilvia KARPATI, Ákos Bányász

Organic & Biomolecular Chemistry, 2010

View PDFchevron_right

Bipyrimidine Photoproducts Rather than Oxidative Lesions Are the Main Type of DNA Damage Involved in the Genotoxic Effect of Solar UVA Radiation †

Jean Cadet

Biochemistry, 2003

View PDFchevron_right

Photoprotection of DNA (in vitro) by acyclothymidine dinucleosides

Abbas Raza

Bioorganic & Medicinal Chemistry Letters, 2013

View PDFchevron_right

Repair of the three main types of bipyrimidine DNA photoproducts in human keratinocytes exposed to UVB and UVA radiations

Jean Cadet

DNA Repair, 2005

View PDFchevron_right

DNA breakage and cell cycle checkpoint abrogation induced by a therapeutic thiopurine and UVA radiation

Reto Brem

Oncogene, 2010

View PDFchevron_right

On the mechanism of photo-induced nucleic acid cleavage using N-aroyloxy-2-thiopyridones

Emmanuel Theodorakis

Tetrahedron Letters, 1998

View PDFchevron_right

Protein Oxidation and DNA Repair Inhibition by 6-Thioguanine and UVA Radiation

Reto Brem

Journal of Investigative Dermatology, 2014

View PDFchevron_right

Synthesis and DNA Photocleavage Activity of S-Alkylated 2-thiopyrimidines Current Trends in Biotechnology and Chemical Research

Ajay Sharma

View PDFchevron_right

Deamination of Cytosine-containing Pyrimidine Photodimers in UV-irradiated DNA

Zvi Livneh

Journal of Biological Chemistry, 1995

View PDFchevron_right

UVB and UVA radiation-mediated damage to isolated and cellular DNA

Jean Cadet

Pure and Applied Chemistry, 2000

View PDFchevron_right

UVB and UVA induced formation of photoproducts within cellular DNA

Jean Cadet

From DNA Photolesions to Mutations, Skin Cancer and Cell Death, 2005

View PDFchevron_right

Sensitized formation of oxidatively generated damage to cellular DNA by UVA radiation

Paolo Di Mascio

Photochemical & Photobiological Sciences, 2009

View PDFchevron_right

Thiothymidine plus low-dose UVA kills hyperproliferative human skin cells independently of their human papilloma virus status

Andrew J Massey

Molecular Cancer Therapeutics, 2007

View PDFchevron_right

Photolysis of N-Hydroxypyridinethiones: A New Source of Hydroxyl Radicals for the Direct Damage of Cell-Free and Cellular DNA

Bernd Epe

Nucleic Acids Research, 1996

View PDFchevron_right

Novel cytotoxic DNA sequence and minor groove targeted photosensitizers: Conjugates of pyrene and netropsin analogues

Michael Wyatt

Bioorganic & Medicinal Chemistry, 1995

View PDFchevron_right

Distribution of UV light-induced damage in a defined sequence of human DNA: detection of alkaline-sensitive lesions at pyrimidine nucleoside-cytidine sequences

Judith Lippke, Lynn Gordon

Proceedings of the National Academy of Sciences, 1981

View PDFchevron_right

Cyclobutane Pyrimidine Dimers are the Main Mutagenic DNA Photoproducts in DNA Repair-deficient Trichothiodystrophy Cells

Alain Sarasin

Cancer Research, 1998

View PDFchevron_right

Cyclobutane pyrimidine dimers are predominant DNA lesions in whole human skin exposed to UVA radiation

Jean Cadet

Proceedings of the National Academy of Sciences, 2006

View PDFchevron_right

Probing photoprotection properties of lipophilic chain conjugated thiourea-aryl group molecules to attenuate ultraviolet-A induced cellular and DNA damages

Sobia Rana

Scientific Reports

View PDFchevron_right

Molecular mechanisms of ultraviolet radiation-induced DNA damage and repair

Madhu Tyagi, Rajesh Rastogi

Journal of nucleic acids, 2010

View PDFchevron_right

Phototoxic Potential of Different DNA Intercalators for Skin Cancer Therapy: In Vitro Screening

Paulo Ribeiro

International Journal of Molecular Sciences, 2023

View PDFchevron_right

DNA repair inhibition by UVA photoactivated fluoroquinolones and vemurafenib

Reto Brem

Nucleic Acids Research, 2014

View PDFchevron_right

Assessment of ultraviolet toxicity depending on DNA-damage using cyclobutane pyrimidine dimer formation in ultraviolet irradiated cells

Dr. Runa Masuma

2014

View PDFchevron_right

Detection of the thietane precursor in the UVA formation of the DNA 6-4 photoadduct

Carlos E. Crespo-Hernández

Nature Communications, 2020

View PDFchevron_right

Monomeric Base Damage Products from Guanine, Adenine, and Thymine Induced by Exposure of DNA to Ultraviolet Radiation

M. Dizdaroglu

Biochemistry, 1995

View PDFchevron_right

Insight in DNA Repair of UV-induced Pyrimidine Dimers by Chromatographic Methods

Jean Cadet

Photochemistry and photobiology, 2017

View PDFchevron_right

Modulation of exogenous and endogenous levels of thioredoxin in human skin fibroblasts prevents DNA damaging effect of ultraviolet A radiation

Christine Didier

Free Radical Biology and Medicine, 2001

View PDFchevron_right

UV wavelength-dependent DNA damage and human non-melanoma and melanoma skin cancer

Gerd P Pfeifer

Photochemical & Photobiological Sciences, 2012

View PDFchevron_right