Differences in the rate of destruction of alkylated RNA, protein, and lipid molecules in normal and tumor cells
Michael Lerman
Bulletin of Experimental Biology and Medicine, 1973
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The development of metabolite transfer between reaggregating Novikoff hepatoma cells
Ross Johnson, Dale Pederson
Experimental Cell Research, 1980
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Different degradation rates of alkylated RNA protein and lipids in normal and tumor cells
Michael Lerman
Cancer research, 1974
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Major Differences between Tumor and Normal Human Cell Fates after Exposure to Chemotherapeutic Monofunctional Alkylator
Andy Tuck, Kandace Williams
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The antitumour activity of alkylating agents is not correlated with the levels of glutathione, glutathione transferase and O6-alkylguanine-DNA-alkyltransferase of human tumour xenografts
Maurizio D'Incalci
European Journal of Cancer, 1998
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Mice, men, mustards and methylated xanthines: the potential role of caffeine and related drugs in the sensitization of human tumours to alkylating agents
John P Murnane
British Journal of Cancer, 1981
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Exposure of HeLa cells to 06-alkylguanines increases sensitivity to the cytotoxic effects of alkylating agents
Christopher Corsico
Biochemical and Biophysical Research Communications, 1985
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The effects of bifunctional alkylating anti-tumor agents on oncogene structure and function in the human tumor cell line Colo 3320 HSR
Bernard Futscher
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DNA damaging and cell proliferative activity of 1-methyl-1-nitrosourea in rat glandular stomach mucosa
C. Furihata
Mutation Research Letters, 1995
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DNA alkylation in the hamster induced by two pancreatic carcinogens
Demetrius Kokkinakis
Cancer research, 1989
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Effect of chlorambucil on synthesis of protein and nucleic acids in tumor-bearing mice
Sanchari Pradhan
Cancer research, 1960
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Cytotoxicity of monofunctional alkylating agents. Methyl methanesulfonate and methyl-N'-nitro-N-nitrosoguanidine have different mechanisms of toxicity for 10T1/2 cells
Joe Grisham
Mutation research, 1983
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Preclinical studies and clinical correlation of the effect of alkylating dose
Beverly Teicher
Cancer research, 1988
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Alkyltransferase transgenic mice: probes of chemical carcinogenesis
Catherine Fan
Mutation Research-fundamental and Molecular Mechanisms of Mutagenesis, 1994
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Accumulation of two alkylating agents, nitrogen mustard and busulfan, by murine leukemia cells in vitro
David Kessel
Biochemical Pharmacology, 1969
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Early Modification of c-myc, Ha-ras and p53 Expressions by Chemical Carcinogens (DMBA, MNU)
Katalin Gombos, István Kiss, Ida Prantner, Timea Varjas
In Vivo, 2009
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Formation and Antitumor Activity of PNU-159682, A Major Metabolite of Nemorubicin in Human Liver Microsomes
Marianna Fantin
Clinical Cancer Research, 2005
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Biochemical Properties of Carcinogen-Metabolizing Enzymes in Cultured Hepatoma Cells
Umberto Marinari, Anna Maria Bassi
Toxicologic Pathology, 1987
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1H MRS markers of tumour growth in intrasplenic tumours and liver metastasis induced by injection of HT-29 cells in nude mice spleen
Luis Lopez
NMR in Biomedicine, 1998
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Histochemical profile of mouse hepatocellular adenomas and carcinomas induced by a single dose of diethylnitrosamine
Peter Bannasch
PubMed, 1991
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O 6 -Methyguanine levels and histopathological changes in the rat esophagus and liver following single and repeated administration of N -nitrosomethylbenzylamin
Gary Stoner
Carcinogenesis, 1996
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Changes in de novo DNA (cytosine-5-)-methyltransferase activity in oncogenically susceptible rat target tissues induced by N-methyl-N-nitrosourea
Annie Leszkowicz
Cancer research, 1986
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S-adenosylmethionine in the chemoprevention and treatment of hepatocellular carcinoma in a rat model
Ryan Park
Hepatology, 2009
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Carcinogen Induced Unscheduled DNA Synthesis in Mouse Hepatocytes
James Klaunig
Toxicologic Pathology, 1984
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Mutagenicity, unscheduled DNA synthesis, and metabolism of 1-nitropyrene in the human hepatoma cell line HepG2
Priya Darshini
Cancer research, 1987
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Antitumor Effect of the Mannich Base(1,3-bis-((3-Hydroxynaphthalen-2-yl)phenylmethyl)urea) on Hepatocellular Carcinoma
Ravikumar Sivanesan
Molecules (Basel, Switzerland), 2016
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Early modification of c-myc, Ha-ras and p53 expressions by N-methyl-N-nitrosourea
Timea Varjas
In Vivo, 2008
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Characterization of increased drug metabolism activity in dimethyl sulfoxide (DMSO)-treated Huh7 hepatoma cells
Susan Uprichard
Xenobiotica, 2009
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Chemoprevention of hepatocarcinogenesis
Maria Simile
Alcohol, 2002
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Mutagenic and chemotherapeutic activity in L1210 leukemia of several monofunctional alkylating agents
Bipin Mehta
Cancer research, 1985
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The relationship of a novel drug-resistant phenotype in C3H10T1/2 cells selected with alkylating agents to neoplastic transformation and ATP metabolism
Eric von Hofe
Cancer Letters, 1997
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Carcinogenesis and nucleic acid alkylation by some oxygenated nitrosamines in rats and hamsters
Joseph Saavedra
Chemico-Biological Interactions, 1988
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