Understanding the mechanism of proteasome 20S core particle gating (original) (raw)

Nanoenzymology of the 20S Proteasome: Proteasomal Actions Are Controlled by the Allosteric Transition †

Maria Gaczynska

Biochemistry, 2002

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A Tetrahedral Transition State at the Active Sites of the 20S Proteasome Is Coupled to Opening of the α-Ring Channel

Maria Gaczynska

Structure, 2009

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Two-substrate association with the 20S proteasome at single-molecule level

Ali Tinazli

The EMBO Journal, 2004

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Mechanism of Gate Opening in the 20S Proteasome by the Proteasomal ATPases

Alfred Goldberg

Molecular Cell, 2008

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The central unit within the 19S regulatory particle of the proteasome

Maria Gaczynska

Nature Structural & Molecular Biology, 2008

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Atomic Force Microscopy Reveals Two Conformations of the 20 S Proteasome from Fission Yeast

Maria Gaczynska

Journal of Biological Chemistry, 2000

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Opening doors into the proteasome

Andrew Vandemark

Nature structural biology, 2000

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A Gated Channel Into the Proteasome Core Particle

Michael Groll

Nature Structural & …, 2000

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Probing Structural Determinants Distal to the Site of Hydrolysis that Control Substrate Specificity of the 20S Proteasome

Michael Groll

Chemistry & Biology, 2002

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Structural Models for Interactions between the 20S Proteasome and Its PAN/19S Activators

Howard Robinson

Journal of Biological Chemistry, 2010

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Stability of the proteasome can be regulated allosterically through engagement of its proteolytic active sites

Roelofs Jeroen

Nature structural & molecular biology, 2007

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Conformational constraints for protein self-cleavage in the proteasome

Michael Groll

Journal of Molecular Biology, 1998

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Near-atomic resolution structural model of the yeast 26S proteasome

Friedrich Foerster

Proceedings of the National Academy of Sciences, 2012

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Dependence of Proteasome Processing Rate on Substrate Unfolding

Philip Coffino

Journal of Biological Chemistry, 2011

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Allosteric coupling between α-rings of the 20S proteasome

Philip Coffino

Nature Communications, 2020

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Structure of the 26S proteasome from Schizosaccharomyces pombe at subnanometer resolution

S. Nickell

2010

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Conformational constraints for protein self-cleavage in the proteasome1

Michael Groll

Journal of Molecular Biology, 1998

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Toward an integrated structural model of the 26S proteasome

S. Nickell

Molecular & cellular proteomics : MCP, 2010

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Observing Protein Degradation by the PAN-20S Proteasome by Time-Resolved Neutron Scattering

Michael Hartlein

Biophysical Journal, 2020

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Insights into the molecular architecture of the 26S proteasome

Andreas Korinek

Proceedings of the National Academy of Sciences, 2009

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Insight into Inhibitor Binding in the Eukaryotic Proteasome: Computations of the 20S CP

Nadia Elghobashi-Meinhardt

International Journal of Molecular Sciences, 2018

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PACemakers of Proteasome Core Particle Assembly

Gisele Souza

Structure, 2008

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The Direction of Protein Entry into the Proteasome Determines the Variety of Products and Depends on the Force Needed to Unfold Its Two Termini

Alfred Goldberg

Molecular Cell, 2012

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The proteasome: a proteolytic nanomachine of cell regulation and waste disposal

Dieter H Wolf

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2004

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Molecular architecture of the 26S proteasome holocomplex determined by an integrative approach

Friedrich Foerster

Proceedings of the National Academy of Sciences, 2012

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Gyre and gimble in the proteasome

Mark Hochstrasser

Proceedings of the National Academy of Sciences

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Docking of the Proteasomal ATPases' Carboxyl Termini in the 20S Proteasome's α Ring Opens the Gate for Substrate Entry

Alfred Goldberg

Molecular Cell, 2007

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The catalytic sites of 20S proteasomes and their role in subunit maturation: A mutational and crystallographic study

Dieter H Wolf

Proceedings of the National Academy of Sciences, 1999

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Proteasome Channel Opening as a Rate-Limiting Step in the Ubiquitin-Proteasome System

Shoshana Bar-nun

Israel Journal of Chemistry, 2006

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Redox Control of 20S Proteasome Gating

Gustavo Silva

2012

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An unstructured initiation site is required for efficient proteasome-mediated degradation

LIN TIAN

Nature Structural & Molecular Biology, 2004

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A role for the proteasome alpha2 subunit N-tail in substrate processing

Maria Gaczynska

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