Microtubules as a target for anticancer drugs (original) (raw)
Microtubule assembly dynamics: An attractive target for anticancer drugs
Krishnan Rathinasamy
IUBMB Life, 2008
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Drugs that target dynamic microtubules: A new molecular perspective
Ritu Aneja
Medicinal Research …, 2011
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Stabilizing versus Destabilizing the Microtubules: A Double-Edge Sword for an Effective Cancer Treatment Option?
Marta Castiglia
Analytical Cellular Pathology, 2015
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Mechanism of Action of Antitumor Drugs that Interact with Microtubules and Tubulin
Mary Jordan
Current Medicinal Chemistry-Anti-Cancer Agents, 2012
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Modulating Microtubule Stability Enhances the Cytotoxic Response of Cancer Cells to Paclitaxel
Ahmed Ahmed
Cancer Research, 2011
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Two antagonistic microtubule targeting drugs act synergistically to kill cancer cells
Julien Vollaire
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Antiangiogenic Concentrations of Paclitaxel Induce an Increase in Microtubule Dynamics in Endothelial Cells but Not in Cancer Cells
Mary Jordan
Cancer Research, 2005
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Synergistic Suppression of Microtubule Dynamics by Discodermolide and Paclitaxel in Non-Small Cell Lung Carcinoma Cells
S. Honore, Mary Jordan
Cancer Research, 2004
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Microtubins: a novel class of small synthetic microtubule targeting drugs that inhibit cancer cell proliferation
Jorge Torres
Oncotarget, 2017
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III-Tubulin Induces Paclitaxel Resistance in Association with Reduced Effects on Microtubule Dynamic Instability
Mary Jordan
Journal of Biological Chemistry, 2004
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Microtubule dynamics: taking aim at a moving target
Mary Jordan
Chemistry & Biology, 1995
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Chemically diverse microtubule stabilizing agents initiate distinct mitotic defects and dysregulated expression of key mitotic kinases
Phillip Crews
Biochemical Pharmacology, 2013
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Microtubule-binding agents: a dynamic field of cancer therapeutics
Mary Jordan
Nature Reviews Drug Discovery, 2010
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Influence of microtubule-associated proteins on the differential effects of paclitaxel and docetaxel
Yves Fromes
Journal of Protein Chemistry, 1996
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An overview of microtubule targeting agents for cancer therapy
Sultan Nacak Baytas
Archives of Industrial Hygiene and Toxicology, 2019
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Comparison of microtubules stabilized with the anticancer drugs cevipabulin and paclitaxel
Akihiko Konagaya
Polymer Journal, 2020
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Pharmacophore Models of Paclitaxel- and Epothilone-Based Microtubule Stabilizing Agents
sangbae lee
Bulletin of the Korean Chemical Society, 2013
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Hitting the brakes: targeting microtubule motors in cancer
Péter Tátrai
British Journal of Cancer, 2015
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Intrinsic and Extrinsic Factors Affecting Microtubule Dynamics in Normal and Cancer Cells
Hanna Fabczak
Molecules
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Microtubule Interactions with Chemically Diverse Stabilizing Agents: Thermodynamics of Binding to the Paclitaxel Site Predicts Cytotoxicity
Isabel Barasoain Blasco
Chemistry & Biology, 2005
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Selective Targeting of Tumorigenic Cancer Cell Lines by Microtubule Inhibitors
Gus Rosania
PLoS ONE, 2009
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Microtubule-targeted agents: When mitochondria become essential to chemotherapy
Manon Carre
Biochimica et Biophysica Acta (BBA) - Bioenergetics, 2011
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Dissecting Paclitaxel–Microtubule Association: Quantitative Assessment of the 2′-OH Group
Susan Bane
Biochemistry, 2013
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Overexpression of Mitotic Centromere–Associated Kinesin Stimulates Microtubule Detachment and Confers Resistance to Paclitaxel
Anutosh Ganguly
Molecular Cancer Therapeutics, 2011
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Suppression of microtubule dynamics by benomyl decreases tension across kinetochore pairs and induces apoptosis in cancer cells
Rathinasamy Krishnan
Febs Journal, 2006
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7-Diethylamino-3(2′-benzoxazolyl)-coumarin is a novel microtubule inhibitor with antimitotic activity in multidrug resistant cancer cells
Hanna Kim
Biochemical Pharmacology, 2009
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Data from TTI-237: A Novel Microtubule-Active Compound with In vivo Antitumor Activity
Danielle Vitale
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CKT0353, a novel microtubule targeting agent, overcomes paclitaxel induced resistance in cancer cells
Milica Pešić
Investigational New Drugs, 2019
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MPC-6827: A Small-Molecule Inhibitor of Microtubule Formation That Is Not a Substrate for Multidrug Resistance Pumps
srinivas kasibhatla
Cancer Research, 2007
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