Comparison of hematological parameters in primary hypertensives and normotensives of Sangareddy (original) (raw)
Related papers
BMC Hematology
Background: Hypertension is a major health problem worldwide. It can lead to cardiovascular disease and also leads to functional disturbances including hematological parameters. The abnormalities of haematological parameters may enhance an end-organ damage. Therefore, the aim of this study was to assess some hematological parameters of hypertensive individuals in comparison with normotensive individuals at University of Gondar hospital, northwest Ethiopia. Methods: A cross sectional comparative study was conducted from October to November 2015 on a total of 126 hypertensive and 126 normotensive individuals at University of Gondar Hospital. All participants after taking informed consent were interviewed for detailed history and 3 ml of blood was collected for hematological test analysis. Independent t-test and the Mann Whitney u-test were used to find out significant difference and Pearson's and Spearman's correlation were used for correlation test. P values less than 0.05 was considered the level of significance. Result: From a total of 252 study subjects, about 67.5% were females. The mean age of study subjects was 50.3 ± 11 years for hypertensive individuals and 49.8 ± 11.6 years for normotensive individuals with range of 18-65 years. In the present study, the median (IQR) value of WBC, RBC, Hgb, HCT, MCV and the mean value of MCHC, RDW, MPV and PDW were significantly higher in hypertensive group compared to apparently healthy normotensive groups. Additionally, WBC, RBC, Hgb, HCT and PLT showed statistically significant positive correlations with blood pressure indices. Platelet count and MCH did not show statistically significant difference between the two groups. Conclusion: Hypertension has impact on hematological parameters. In this study, the mean and median values of haematological parameters in hypertensive individuals were significantly different compared to apparently healthy normotensive individuals. Hence, hematological parameters can be used to monitor the prognosis of the disease and manage hypertensive related complications, and it is important to assess hematological parameters for hypertensive individuals which may help to prevent complications associated hematological disorders.
PLoS ONE, 2021
Background Hypertension is the major public health concern; leading to cardiovascular disease. It is associated with alteration in hematological parameters which may lead to end-organ damage. Thus, this study aimed to compare hematological parameters between hypertensive and normotensive adult groups in Harar, eastern Ethiopia. Methods A comparative cross-sectional study was conducted from January to March, 2020 at Jugel and Hiwotfana Specialized University hospital, Harar, eastern Ethiopia. Convenient sampling technique was used to recruit 102 hypertensive patients from the two hospitals and 102 apparently healthy blood donors. Participant’s socio-demographic and clinical information were collected using pre-tested structured questionnaire. Blood sample were collected and analyzed by Beckman Coulter DxH 500 analyzer for complete blood count. The data were entered and analyzed using SPSS version 23. Independent t-test and Mann Whitney u-test was used for comparison between groups. S...
Open Journal of Blood Diseases
Background: Hypertension is a persistent elevation of blood pressure in the arteries which if not properly managed can lead to stroke, heart failure, atrial fibrillation, peripheral vascular disease and other life threatening outcomes. This study investigated some haematological parameters of Primary hypertensive subjects. Objectives: To compare some haematological parameters (haematocrit, haemoglobin concentration, Platelets count, White Blood Cells count, red blood cell count and Red Cells Indices between hypertensive and normotensive subjects. Materials and methods: Blood samples were collected from 76 known hypertensive subjects between 30-70 years attending the Cardiology clinic of the University of Abuja Teaching Hospital Gwagwalada. Another 37 normotensive subjects between 30-65 years served as the control. All subjects gave their consents. Platelets count, Haemoglobin estimation, Packed Cell Volume, Red Blood Cell Count, Mean Cell Volume, Mean Cell Haemoglobin, Mean Cell Haemoglobin Concentration and White Blood Cell count were determined using Mythic 22 five parts haematology analyzer. Results: Results for Hypertensive and Control subjects were, White
Hematological Parameters in Cardiovascular Diseases
2018
Background: Cardiovascular diseases are one of the leading causes for morbidity and mortality worldwide. They are mainly caused by atherosclerosis and its complications. Limited literature is available on the role of various haematological parameters.Our objective was to study various haematological parameters like RBC count, Haemoglobin, Haematocrit, Mean Corpuscular Volume (MCV), Mean Corpuscular Haemoglobin (MCH), RedCell Distribution Width (RDW) in patients with Coronary Artery Disease (CAD). Methods: This was a descriptive study carried out on patients with CAD admitted to Sri Jayadeva Institute of Cardiovascular Sciences and Research, KRHospital Campus, Mysore, India in the age range of 30–60 years. Patients with impaired renal or hepatic function, known congenital heart disease/valvular heart diseases, known case of anaemia or being treated for anaemia, prolonged drug intake, thyroid disorders were excluded from the study. Blood samples were collected in an EDTA vaccutainer...
Haematological reference ranges are often influenced by individual variables, such as race, age, gender and dietary habits. In addition, ecological factors such as climate and altitudemight affect the parameters, while variations in instrumentation techniques and laboratory personnel involved also contribute to the measurements. Therefore, the currently used reference ranges, which were originally adopted from other countries and mainly refer to European subjects, might be misleading in some cases. This study is an attempt to establish haematological reference ranges for male subjectsfrom Eastern India. Haematological tests, using an automated haematology analyzer, were carried out on 528blood samples from healthy male donors. The population was found to exhibit lowerhaemoglobin (HGB) and platelet (PLT) contents as compared to the standard reference values, although the difference was statistically significant only for the platelet count. Nevertheless, the digression from the international range of data was clinically significant, except for the white blood cells (WBC) and red blood cells (RBC) counts. Finally, the respective reference values for HGB, RBC and hematocrit (HCT) were found to vary significantly with the age group of the subjects. It is expected that the study will facilitate the interpretation and reporting of haematological parameters in Eastern India.
The Haemorheological Parameters of Hypertensive --Compared with Normotensives
Sex variations in some haemorheological parameters: Haematocrit (Hct), Erythrocyte Sedimentation Rate (ESR), Hemoglobin concentration (Hbc), Fibrinogen concentration (FC), Relative Plasma Viscosity (RPV) and Whole Blood Relative Viscosity (WBRV) were determined in 30 male and 20 female hypertensive subjects without complications, aged between 30 and 70 years. 30 male and 20 female normotensive subjects aged between 29 and 71 years, matched for age, weight and height with the hypertensive group served as control. In both groups all the parameters were determined using methods previously described by various workers (Chien, 1977). Results obtained in normotensives showed a significantly lower systolic blood pressure , mean arterial pressure, haematocrit and whole blood relative viscosity and a significantly higher erythrocyte sedimentation rate in female subjects compared to male subjects , no significant correlation was found between any of the haemorheological parameters and the blo...
Prevalence of hypertension among adults of Midnapore, West Bengal, India: A comparison between sexes
Present study aims to find out the prevalence of hypotension and hypertension among Bengalee adult males and females of Midnapore, West Bengal, India. A multistage sampling technique was used by a house-to-house survey among 498 (Male=344, Female=154) adult individuals. It was evident from the present result that hypertensive cases were found to be more frequent among males with respect to Systolic Blood Pressure (SBP) and Diastolic Blood Pressure DBP. However, hypotensive cases were found to be more frequent among females, only in DBP. Furthermore, age seems to be a potential risk factor for the development of hypertension in the studied population.
CLSI-Derived Hematology Reference Intervals for Healthy Males in Eastern India
Haematological reference ranges are often influenced by individual variables, such as race, age, gender and dietary habits. In addition, ecological factors such as climate and altitudemight affect the parameters, while variations in instrumentation techniques and laboratory personnel involved also contribute to the measurements. Therefore, the currently used reference ranges, which were originally adopted from other countries and mainly refer to European subjects, might be misleading in some cases. This study is an attempt to establish haematological reference ranges for male subjectsfrom Eastern India. Haematological tests, using an automated haematology analyzer, were carried out on 528blood samples from healthy male donors. The population was found to exhibit lowerhaemoglobin (HGB) and platelet (PLT) contents as compared to the standard reference values, although the difference was statistically significant only for the platelet count. Nevertheless, the digression from the international range of data was clinically significant, except for the white blood cells (WBC) and red blood cells (RBC) counts. Finally, the respective reference values for HGB, RBC and hematocrit (HCT) were found to vary significantly with the age group of the subjects. It is expected that the study will facilitate the interpretation and reporting of haematological parameters in Eastern India.
Association of hematocrit with blood pressure and hypertension
Journal of clinical laboratory analysis, 2017
Hypertension (HTN) is a risk factor for stroke, renal failure, and cardiovascular disease. The association between biochemical and hematological parameters with high blood pressure may provide a more precise approach to risk prediction conferred by HTN in these patients. The aim of current study was to explore whether biochemical and hematological parameters are associated with HTN in a cohort study with a 7-year follow-up. A total of 9808 individuals were enrolled and recruited as part of the Mashhad Stroke and Heart Atherosclerotic Disorders (MASHAD) cohort study, and biochemical and hematological factors were measured in all subjects. Univariate and multivariate logistic regression analysis were performed to determine the association of biochemical and hematological parameters with HTN. Several biochemical parameters including fasting plasma glucose (FBG), serum high-sensitivity C-reactive protein (hs-CRP), triglyceride (TG), total cholesterol (TC), low-density lipoprotein choles...
International Journal of TROPICAL DISEASE & Health, 2020
Aim: The Complete Blood Count (CBC) among hypertensive subjects in Isiala Mbano, Imo State, Nigeria West Africa were studied. Methodology: The American College of Cardiology/American Heart Association (2017) current definition of hypertension was used to ascertain, diagnoses and assigned eighty (80)hypertensive subjects after three different consecutive blood pressure check into tests groups. Other blood pressure measures such as pulse pressure and mean arterial pressure were calculated appropriately. Venous blood samples were collected with 5mls syringe and immediately emptied into EDTA container for complete blood count analysis. Results: The results showed increase in RBC count, HB, PCV and decrease in MCV among hypertensive subjects compared with normotensive subjects. It was statistically insignificant in all age groups. No changes were seen in MCHC and MCH. The results also, showed increase in PLTS count. The increase in PLTS count was statistically significant at P<0.05 an...