Dopamine D2 heteroreceptor complexes and their receptor-receptor interactions in ventral striatum: Novel targets for antipsychotic drugs
Wilber Romero-Fernandez, Michael Di Palma, Sergio Tanganelli, Dasiel O Borroto-Escuela, Luigi Agnati
2014
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Atypical and typical antipsychotic drug interactions with the dopamine D2 receptor
Erik Hjerde, Ingebrigt Sylte
European Journal of Medicinal Chemistry, 2005
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Novel Dopamine Receptor Subtypes as Targets for Antipsychotic Drugs
Jorge Diaz
Annals of the New York Academy of Sciences, 1995
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Role of the extracellular amino terminus and first membrane-spanning helix of dopamine D1 and D5 receptors in shaping ligand selectivity and efficacy
Mario Tiberi
Cellular Signalling, 2010
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S33138 [N-[4-[2-[(3aS,9bR)-8-cyano-1,3a,4,9b-tetrahydro[1]-benzopyrano[3,4-c]pyrrol-2(3H)-yl)-ethyl]phenylacetamide], A Preferential Dopamine D3 versus D2 Receptor Antagonist and Potential Antipsychotic Agent: I. Receptor-Binding Profile and Functional Actions at G-Protein-Coupled Receptors
Adrian Newman-Tancredi
Journal of Pharmacology and Experimental Therapeutics, 2007
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Antipsychotic Drug Responsiveness and Dopamine Receptor Signaling; Old Players and New Prospects
Martin Beaulieu
Frontiers in Psychiatry, 2019
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IN-SILICO PROTEIN LIGAND INTERACTION STUDY OF TYPICAL ANTIPSYCHOTIC DRUGS AGAINST DOPAMINERGIC D2 RECEPTOR
PRATAP KUMAR PARIDA
2013
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The role of D1–D2 receptor hetero-dimerization in the mechanism of action of clozapine
Maciej Kusmider
European Neuropsychopharmacology, 2008
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Potential Mechanisms for Why Not All Antipsychotics Are Able to Occupy Dopamine D3 Receptors in the Brain in vivo
Dr. István Laszlovszky
Frontiers in Psychiatry
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Decoding the Signaling of a GPCR Heteromeric Complex Reveals a Unifying Mechanism of Action of Antipsychotic Drugs
Davide Provasi
Cell, 2011
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The Importance of Dopamine D4 Receptors in the Action and Development of Antipsychotic Agents
Gavin Reynolds
Drugs, 1996
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Canonical and Non-Canonical Antipsychotics’ Dopamine-Related Mechanisms of Present and Next Generation Molecules: A Systematic Review on Translational Highlights for Treatment Response and Treatment-Resistant Schizophrenia
Andrea de Bartolomeis
International Journal of Molecular Sciences
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Antipsychotic Haloperidol Binding to the Human Dopamine D3 Receptor: Beyond Docking Through QM/MM Refinement Toward the Design of Improved Schizophrenia Medicines
Ewerton Caetano
ACS Chemical Neuroscience, 2014
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Distinct Dopamine D2 Receptor Antagonists Differentially Impact D2 Receptor Oligomerization
Elise Wouters
International Journal of Molecular Sciences
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Mechanism of action of clozapine in the context of dopamine D1-D2 receptor hetero-dimerization--a working hypothesis
Maciej Kusmider
Pharmacological reports : PR
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Dopamine and Serotonin Receptor Binding and Antipsychotic Efficacy
Aaron Logue
Neuropsychopharmacology, 2007
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The D2R-DISC1 protein complex and associated proteins are altered in schizophrenia and normalized with antipsychotic treatment
James Samsom
Journal of Psychiatry and Neuroscience
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QSAR-CoMSIA applied to antipsychotic drugs with their dopamine D2 and serotonine 5HT2A membrane receptors
Daniel Duda-Seiman
Journal of the Serbian Chemical Society, 2011
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Dopamine D2S and D2L receptors may differentially contribute to the actions of antipsychotic and psychotic agents in mice
Dubravka Hranilovic
Molecular Psychiatry, 2002
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Agonist and antagonist properties of antipsychotics at human dopamine D4.4 receptors: G-protein activation and K+ channel modulation in transfected cells
Jean-Claude MARTEL
International Journal of Neuropsychopharmacology - INT J NEUROPSYCHOPHARMACOL, 2008
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Beyond the dopamine receptor: novel therapeutic targets for treating schizophrenia
Alo Basu
Dialogues in clinical neuroscience, 2010
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The Effect of Antipsychotics on the High-Affinity State of D2 and D3 Receptors
Ariel Graff-Guerrero
Archives of General Psychiatry, 2009
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Possible Implications of the Dopamine D3 Receptor In Schizophrenia and In Antipsychotic Drug Actions
jorge diaz
Brain Research Reviews, 2000
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Occupancy of dopamine D2 receptors by the atypical antipsychotic drugs risperidone and olanzapine: theoretical implications
Anissa Abi-Dargham
Psychopharmacology, 2004
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History of the Discovery of the Antipsychotic Dopamine D2 Receptor: A Basis for the Dopamine Hypothesis of Schizophrenia
Bertha Madras
Http Dx Doi Org 10 1080 0964704x 2012 678199, 2013
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Intrinsic Efficacy of Antipsychotics at Human D2, D3, and D4 Dopamine Receptors: Identification of the Clozapine Metabolite N-Desmethylclozapine as a D2/D3 Partial Agonist
Norman Nash
Journal of Pharmacology and Experimental Therapeutics, 2005
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Receptor reserve-dependent properties of antipsychotics at human dopamine D2 receptors
Robert McQuade
European Journal of Pharmacology, 2009
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Association study between the dopamine D4 receptor gene and schizophrenia
Philip Cola
American Journal of Medical Genetics, 1995
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Receptor mechanisms in the treatment of schizophrenia
Gavin Reynolds
Journal of Psychopharmacology, 2004
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Antipsychotic drugs which elicit little or no Parkinsonism bind more loosely than dopamine to brain D2 receptors, yet occupy high levels of these receptors
P. Seeman
Molecular Psychiatry, 1998
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