Is fibroblast growth factor signaling pathway a victim of receptor tyrosine kinase inhibition in pulmonary parenchymal and vascular remodeling? (original) (raw)

Increased FGF1-FGFRc expression in idiopathic pulmonary fibrosis

Ingrid Henneke, Beate Schneider, Stefanie Hezel, Zaneta Sibinska

Respiratory research, 2015

View PDFchevron_right

Epidermal Growth Factor Receptor Tyrosine Kinase Inhibition Augments a Murine Model of Pulmonary Fibrosis1

Kazutetsu Aoshiba

2003

View PDFchevron_right

Role for dysregulated endothelium- derived FGF2 signaling in progression of pulmonary hypertension

Gerald Simonneau

Revue des Maladies Respiratoires, 2008

View PDFchevron_right

Endothelial-derived FGF2 contributes to the progression of pulmonary hypertension in humans and rodents

Christophe Guignabert

Journal of Clinical Investigation, 2009

View PDFchevron_right

Specific Inhibitors of Platelet-Derived Growth Factor or Epidermal Growth Factor Receptor Tyrosine Kinase Reduce Pulmonary Fibrosis in Rats

Morgan James

American Journal of Pathology, 1999

View PDFchevron_right

Proliferation of Pulmonary Interstitial Fibroblasts Is Mediated by Transforming Growth Factor-β1-induced Release of Extracellular Fibroblast Growth Factor-2 and Phosphorylation of p38 MAPK and JNK

Nasreen Khalil

Journal of Biological Chemistry, 2005

View PDFchevron_right

Proliferation of Pulmonary Interstitial Fibroblasts Is Mediated by Transforming Growth Factor-beta1-induced Release of Extracellular Fibroblast Growth Factor-2 and Phosphorylation of p38 MAPK and JNK

Nasreen Khalil

Journal of Biological Chemistry, 2005

View PDFchevron_right

Autocrine Fibroblast Growth Factor-2 Signaling Contributes to Altered Endothelial Phenotype in Pulmonary Hypertension

Laurence Dewachter, Christophe Guignabert

American Journal of Respiratory Cell and Molecular Biology, 2011

View PDFchevron_right

Endothelial Hif Signaling Regulates Pulmonary Fibrosis-Associated Pulmonary Hypertension

Megha Talati

American Journal of Physiology - Lung Cellular and Molecular Physiology, 2015

View PDFchevron_right

VEGF ameliorates pulmonary hypertension through inhibition of endothelial apoptosis in experimental lung fibrosis in rats

Jack Gauldie, Peter Margetts, Kjetil Ask

Journal of Clinical Investigation, 2009

View PDFchevron_right

FGF signaling is required for pulmonary homeostasis following hyperoxia

Isamu Hokuto

AJP: Lung Cellular and Molecular Physiology, 2004

View PDFchevron_right

Interruption of vascular endothelial growth factor receptor 2 signaling induces a proliferative pulmonary vasculopathy and pulmonary hypertension

Bassam Redwan

Basic Research in Cardiology, 2020

View PDFchevron_right

Targeting Bronchopulmonary Dysplasia-Associated Pulmonary Hypertension (BPD-PH): Potential Role of the FGF Signaling Pathway in the Development of the Pulmonary Vascular System

xuran chu

Cells

View PDFchevron_right

Antifibrotic role of vascular endothelial growth factor in pulmonary fibrosis

Jack a. Elias

JCI insight, 2017

View PDFchevron_right

Expression of Fibroblast Growth Factor 9 in Normal Human Lung and Idiopathic Pulmonary Fibrosis

E. Coffey

Journal of Histochemistry & Cytochemistry, 2013

View PDFchevron_right

Casein Kinase 1δ/ε Inhibitor, PF670462 Attenuates the Fibrogenic Effects of Transforming Growth Factor-β in Pulmonary Fibrosis

Fernando Jativa

Frontiers in pharmacology, 2018

View PDFchevron_right

Key Role of the Endothelial TGF-β/ALK1/Endoglin Signaling Pathway in Humans and Rodents Pulmonary Hypertension

Elie Fadel

PLoS ONE, 2014

View PDFchevron_right

Inflammation, Growth Factors, and Pulmonary Vascular Remodeling

sonia mamani flores

Journal of the American College of Cardiology, 2009

View PDFchevron_right

Protein tyrosine phosphatase-α amplifies transforming growth factor-β-dependent profibrotic signaling in lung fibroblasts

Jan Sap

American Journal of Physiology-Lung Cellular and Molecular Physiology

View PDFchevron_right

Evidence for lung repair and regeneration in humans: key stem cells and therapeutic functions of fibroblast growth factors

xuran chu

Frontiers of Medicine

View PDFchevron_right

Endothelial FGF signaling is protective in hypoxia-induced pulmonary hypertension

Isabel Shen

Journal of Clinical Investigation, 2021

View PDFchevron_right

FGF-1 Activates several Signaling Pathways as an Antifibrogenic Mediator in Human Lung Fibroblasts

Bettina Sommer

2020

View PDFchevron_right

Sequential expression of IGF-IB followed by active TGF- 1 induces synergistic pulmonary fibroproliferation in vivo

Graciela Andonegui

AJP: Lung Cellular and Molecular Physiology, 2012

View PDFchevron_right

New Molecular Targets of Pulmonary Vascular Remodeling in Pulmonary Arterial Hypertension

Christophe Guignabert

CHEST Journal, 2015

View PDFchevron_right

Vascular Endothelial Growth Factor Receptor 3 Signaling Contributes to Angioobliterative Pulmonary Hypertension

Jennifer Drake

Pulmonary Circulation, 2015

View PDFchevron_right

Fibroblast growth factor-1 attenuates TGF-β1-induced lung fibrosis

Chiko Shimbori

The Journal of Pathology, 2016

View PDFchevron_right

Genomic Profile of Matrix and Vasculature Remodeling in TGF- Induced Pulmonary Fibrosis

George Leikauf

American Journal of Respiratory Cell and Molecular Biology, 2007

View PDFchevron_right

Therapeutic effect of a peptide inhibitor of TGF-� on pulmonary fibrosis

Javier Dotor

Cytokine, 2011

View PDFchevron_right

Inhibition of platelet-derived growth factor signaling attenuates pulmonary fibrosis

Kenneth Lipson, Minglun Li

Journal of Experimental Medicine, 2005

View PDFchevron_right

Pathogenetic pathways and novel pharmacotherapeutic targets in idiopathic pulmonary fibrosis

Athanasia Pataka

Pulmonary Pharmacology & Therapeutics, 2007

View PDFchevron_right